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Custom Cell
Isolation
Adding Precision to Research
www.kosheeka.com
Custom Cell Isolation
Isolation of cells customized to research study.
Refers mostly to primary cells.
Types of in vitro cells based
on properties
Primary cells:
1.Definite life span
2.Derived from tissue
3.Retain tissue characteristics
Cancer cells
4.Indefinite life span
5.Derived from cancer cells or created in a lab
Primary source:
1.Derived from tissue
2.Retain tissue characteristics
3.Example: primary cells, cancer cells
Secondary source:
4.Derived from isolated cells
5.Only have a few tissue characteristics
6.Examples: cell lines
Types of vitro cell source
Customization
Customization refers to the
specificity of cells with respect to:
1.Tissue
2.Animal model
3.Human donor profile (gender, age,
medical history)
Example: Drugs considered safe on
hepatocytes were found to be toxic
to other organs.
Therefore, drug screening should
occur on other tissue cells.
Cells show variations with tissue, animal models, and donor
characteristics.
Custom cells can add precision to research.
Results can be translated to tissue and disease.
Can narrow down the results to a particular population cohort.
Data is more reliable and specific.
Save time and money during clinical studies by including only a particular
group of the population.
Why are Custom Cells Required?
Challenges in custom cell isolation in the lab
Low yield
Inconsistencies between repeated isolations
Purity is compromised
High chance of contamination
Non-standardized protocol
Huge cost, time, and labor investment.
Custom cell isolation services
They provide custom cells at a reasonable cost.
Benefits of custom cell separation services:
1.High yield and purity of cells.
2.Batch-to-batch consistency ensures the reproducibility of results.
3.Screening for contamination
4.It saves time, money, and effort.
5.Employ standard protocols and manufacturing practices.
Conclusion
Cells vary in genotype from different
sources.
Thus, custom cell use will soon become
the routine in precision cell culture
research.
In-house cell isolation is challenging.
Therefore, the private sector has begun
providing custom cell separation
services.
It will considerably enhance the data
reliability and accelerate their clinical
translation.
www.kosheeka.com
Info@kosheeka.com
A-102, Sector-5 Noida-201301,
UP, India
+91-9654321400
Contact Us
THANK YOU
For watching this presentation

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Custom Cell Isolation: Adding Precision to Research

  • 1. Custom Cell Isolation Adding Precision to Research www.kosheeka.com
  • 2. Custom Cell Isolation Isolation of cells customized to research study. Refers mostly to primary cells.
  • 3. Types of in vitro cells based on properties Primary cells: 1.Definite life span 2.Derived from tissue 3.Retain tissue characteristics Cancer cells 4.Indefinite life span 5.Derived from cancer cells or created in a lab
  • 4. Primary source: 1.Derived from tissue 2.Retain tissue characteristics 3.Example: primary cells, cancer cells Secondary source: 4.Derived from isolated cells 5.Only have a few tissue characteristics 6.Examples: cell lines Types of vitro cell source
  • 5. Customization Customization refers to the specificity of cells with respect to: 1.Tissue 2.Animal model 3.Human donor profile (gender, age, medical history) Example: Drugs considered safe on hepatocytes were found to be toxic to other organs. Therefore, drug screening should occur on other tissue cells.
  • 6. Cells show variations with tissue, animal models, and donor characteristics. Custom cells can add precision to research. Results can be translated to tissue and disease. Can narrow down the results to a particular population cohort. Data is more reliable and specific. Save time and money during clinical studies by including only a particular group of the population. Why are Custom Cells Required?
  • 7. Challenges in custom cell isolation in the lab Low yield Inconsistencies between repeated isolations Purity is compromised High chance of contamination Non-standardized protocol Huge cost, time, and labor investment. Custom cell isolation services They provide custom cells at a reasonable cost. Benefits of custom cell separation services: 1.High yield and purity of cells. 2.Batch-to-batch consistency ensures the reproducibility of results. 3.Screening for contamination 4.It saves time, money, and effort. 5.Employ standard protocols and manufacturing practices.
  • 8. Conclusion Cells vary in genotype from different sources. Thus, custom cell use will soon become the routine in precision cell culture research. In-house cell isolation is challenging. Therefore, the private sector has begun providing custom cell separation services. It will considerably enhance the data reliability and accelerate their clinical translation.
  • 9. www.kosheeka.com Info@kosheeka.com A-102, Sector-5 Noida-201301, UP, India +91-9654321400 Contact Us THANK YOU For watching this presentation