This document outlines various danger signs in newborns that require prompt medical attention. It discusses signs like lethargy, poor feeding, prolonged capillary refill time, respiratory distress, hypothermia, cyanosis, vomiting, diarrhea, failure to pass urine or meconium, abnormal weight loss, and signs that could indicate conditions like cardiac disease or tracheo-esophageal fistula. Early detection and treatment of sick newborns is important to prevent high mortality, but diagnosis can be difficult due to non-specific signs, especially in preterm or low birth weight babies. Proper assessment of danger signs and timely referral is necessary to care for newborns with illnesses.