The document comprises the proceedings of the First International Conference on Data Mining and Big Data (DMBd 2016), held in Bali, Indonesia, focusing on the theme 'Serving Life with Data Science.' It discusses the significance of data mining techniques in extracting valuable information from large data sets and addresses challenges related to big data analytics. The conference featured 115 submissions from 36 countries, with 57 papers selected for publication, emphasizing innovations in data mining and intelligent computing.