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Deep Brain Stimulation
Presented by:
Debasish Mondal
4th year BME,NSEC
4/7/2017 1Deep Brain Stimulation
CONTENTS
• INTRODUCTION
• DISEASES TREATED USING DBS
• COMPONENTS
• PLACEMENT OF THE COMPONENTS
• METHODOLOGY OF SURGERY
• LIMITATIONS OF DBS SURGERY
• RISK OF DBS SURGERY
• FUTURE SCOPE AND ENHANCEMENT
• CONCLUSIONS
• MANUFACTURING COMPANIES
• REFERENCES
4/7/2017 2Deep Brain Stimulation
What is Deep Brain Stimulation?
• Deep Brain Stimulation(DBS) is a surgical
treatment which implants a medical device
called a Brain Pacemaker.
• DBS sends electrical impulse to
specific parts of the brain which
need to be stimulated
4/7/2017 3Deep Brain Stimulation
Illnesses Treated
DBS in selected brain regions has provided
effective benefits for the diseases such as,
(i) Parkinson’s Disease
(ii) Chronic pain
(iii) Tremor
(iv) Dystonia
4/7/2017 4Deep Brain Stimulation
Target sites of Brain
4/7/2017 5Deep Brain Stimulation
Components of DBS
The pacemaker consist of
• Electrodes
• Lead wire
• Pulse generator
4/7/2017 6Deep Brain Stimulation
Methodology of Surgery
• Step 1:Attachment of stereotactic frame.
• Step 2: Take MRI or CT scan
• Step 3: Skin and Skull incision
• Step 4: Insert electrode in the brain
• Step 5. Stimulate the brain cells
• Step 6: Closure
4/7/2017 7Deep Brain Stimulation
Fig-I Fig-II
Fig-III Fig-IV
4/7/2017 8Deep Brain Stimulation
Limitations of DBS surgery
• It is expensive
• The selection of patients. DBS is not used in
the following patients,
 Patients with a previous Surgical
Ablation procedure
Patients who are pregnant
Patients under the age of 18 and above
the age of 75.
4/7/2017 9Deep Brain Stimulation
Risks
Risks associated with surgery
• Intracranial Bleeds (12%)
• Seizures (3%)
• Headaches (25%)
• Infection (6%)
Device complications
• Probe replacement (9%)
• Wire replacement (6%)
• Repositioning of the probe (8%)
• Replacement of pulse generator (17%)
• Risk of Death < 1%
4/7/2017 10Deep Brain Stimulation
Benefits
• Reduce their medications , thus minimizing
the side effects of drugs.
• Electrical impulses can be adjusted.
• Both cardiac pacemaker and brain pacemaker
can be used simultaneously by the same
person.
4/7/2017 11Deep Brain Stimulation
Future scope and Enhancement
• Focuses on,
The device which automatically senses the
need for increased voltage.
Improving longevity.
Reduction in size.
Reduction in cost.
Low risk.
4/7/2017 12Deep Brain Stimulation
Manufacturing companies
4/7/2017 13Deep Brain Stimulation
Conclusions
• Advances in the neurosciences will continue
to drive the applications of DBS.
• Finally, innovations in biomedical engineering
and technology will continue to be applied to
DBS.
• The ideal platform for the development of
these innovations is the active collaboration
between basic scientists, engineers and
clinicians.
4/7/2017 14Deep Brain Stimulation
References
• http://www.medscape.com/viewarticle/813942_3
• https://www.ncbi.nlm.nih.gov/pubmed/24175861
• https://en.wikipedia.org/wiki/Dystonia
• http://journal.frontiersin.org/article/10.3389/fnins.2016.00
173/full
• http://alliancebiomedica.com/index.php?route=product
• BOOK: Clinical Physiology By U K Mishra & J Kalita
4/7/2017 15Deep Brain Stimulation
4/7/2017 16Deep Brain Stimulation

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Deep brain stimulation presentation

  • 1. Deep Brain Stimulation Presented by: Debasish Mondal 4th year BME,NSEC 4/7/2017 1Deep Brain Stimulation
  • 2. CONTENTS • INTRODUCTION • DISEASES TREATED USING DBS • COMPONENTS • PLACEMENT OF THE COMPONENTS • METHODOLOGY OF SURGERY • LIMITATIONS OF DBS SURGERY • RISK OF DBS SURGERY • FUTURE SCOPE AND ENHANCEMENT • CONCLUSIONS • MANUFACTURING COMPANIES • REFERENCES 4/7/2017 2Deep Brain Stimulation
  • 3. What is Deep Brain Stimulation? • Deep Brain Stimulation(DBS) is a surgical treatment which implants a medical device called a Brain Pacemaker. • DBS sends electrical impulse to specific parts of the brain which need to be stimulated 4/7/2017 3Deep Brain Stimulation
  • 4. Illnesses Treated DBS in selected brain regions has provided effective benefits for the diseases such as, (i) Parkinson’s Disease (ii) Chronic pain (iii) Tremor (iv) Dystonia 4/7/2017 4Deep Brain Stimulation
  • 5. Target sites of Brain 4/7/2017 5Deep Brain Stimulation
  • 6. Components of DBS The pacemaker consist of • Electrodes • Lead wire • Pulse generator 4/7/2017 6Deep Brain Stimulation
  • 7. Methodology of Surgery • Step 1:Attachment of stereotactic frame. • Step 2: Take MRI or CT scan • Step 3: Skin and Skull incision • Step 4: Insert electrode in the brain • Step 5. Stimulate the brain cells • Step 6: Closure 4/7/2017 7Deep Brain Stimulation
  • 8. Fig-I Fig-II Fig-III Fig-IV 4/7/2017 8Deep Brain Stimulation
  • 9. Limitations of DBS surgery • It is expensive • The selection of patients. DBS is not used in the following patients,  Patients with a previous Surgical Ablation procedure Patients who are pregnant Patients under the age of 18 and above the age of 75. 4/7/2017 9Deep Brain Stimulation
  • 10. Risks Risks associated with surgery • Intracranial Bleeds (12%) • Seizures (3%) • Headaches (25%) • Infection (6%) Device complications • Probe replacement (9%) • Wire replacement (6%) • Repositioning of the probe (8%) • Replacement of pulse generator (17%) • Risk of Death < 1% 4/7/2017 10Deep Brain Stimulation
  • 11. Benefits • Reduce their medications , thus minimizing the side effects of drugs. • Electrical impulses can be adjusted. • Both cardiac pacemaker and brain pacemaker can be used simultaneously by the same person. 4/7/2017 11Deep Brain Stimulation
  • 12. Future scope and Enhancement • Focuses on, The device which automatically senses the need for increased voltage. Improving longevity. Reduction in size. Reduction in cost. Low risk. 4/7/2017 12Deep Brain Stimulation
  • 14. Conclusions • Advances in the neurosciences will continue to drive the applications of DBS. • Finally, innovations in biomedical engineering and technology will continue to be applied to DBS. • The ideal platform for the development of these innovations is the active collaboration between basic scientists, engineers and clinicians. 4/7/2017 14Deep Brain Stimulation
  • 15. References • http://www.medscape.com/viewarticle/813942_3 • https://www.ncbi.nlm.nih.gov/pubmed/24175861 • https://en.wikipedia.org/wiki/Dystonia • http://journal.frontiersin.org/article/10.3389/fnins.2016.00 173/full • http://alliancebiomedica.com/index.php?route=product • BOOK: Clinical Physiology By U K Mishra & J Kalita 4/7/2017 15Deep Brain Stimulation
  • 16. 4/7/2017 16Deep Brain Stimulation