This document discusses the design and analysis of CMOS image sensors, focusing on a high-speed simulation methodology that significantly reduces simulation time from 16ms to 0.225μs using a SPICE model in Cadence Design Platform. It contrasts the features, advantages, and disadvantages of CCD and CMOS image sensors, highlighting their different applications and performances. The paper concludes with results demonstrating the effectiveness of the proposed simulation approach in improving time efficiency for pixel configurations.