This document discusses blocking and confounding in 2k factorial designs. It explains that blocking is used to reduce noise in experiments, and confounding involves assigning treatments to experimental units in a way that balances out systematic errors. The document provides examples of chemical yield, filtration rate, and etching process experiments to illustrate 2k factorial designs with different numbers of blocks and how confounding works. It demonstrates randomization techniques and shows experimental design layouts. The overall purpose is to explain how to design experiments with blocks and use confounding to make comparisons between treatment combinations more reliable.
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