Ventilator Associated Pneumonia (VAP) is a common nosocomial infection that develops in patients on mechanical ventilation. VAP increases mortality, length of stay, and medical costs. Risk factors include prolonged intubation and underlying patient health issues. Symptoms include cough, fever, purulent sputum, and new lung infiltrates. Evidence-based strategies to prevent VAP include oral care, silver coated endotracheal tubes, elevating the head of the bed, and using ventilator bundles.