The document provides eight steps for developing an effective outline for a scientific manuscript: 1) Develop a central message of the manuscript in 1 sentence. 2) Define the materials, methods, population, and sampling used in the study. 3) Summarize the known problems, questions, and what was done to answer them. 4) List the principal findings and results. 5) Describe the conclusions and implications of the findings. 6) Organize related ideas together and provide details and analysis to support each point. 7) Identify references pertaining to each point. 8) Develop an introduction that conveys the purpose, methods, findings and implications of the study based on the outline.