Enamel is the hardest tissue in the body and is derived from the inner enamel epithelium. It is composed mainly of hydroxyapatite crystals and proteins. Enamel is thickest at the incisal edges and cusp tips and thins cervically. Healthy thick enamel appears bluish white while thin enamel near the dentin looks more yellow. Enamel prisms (rods) vary in number between teeth and their twisted structure in cuspal areas adds strength. The rods are surrounded by interprismatic substance and have transverse striations. Enamel is selectively permeable but not impermeable to ions.