Epiphora is caused by impairment of lacrimal drainage leading to excess tearing. It can be due to anatomical issues obstructing tear drainage pathways or functional issues with the lacrimal pump. Common anatomical causes include punctal, canalicular, lacrimal sac, or nasolacrimal duct obstructions from congenital abnormalities, infections, trauma, tumors, or other conditions. A patient's history and external/slit lamp exams can provide clues to the cause. Diagnostic tests like dye disappearance tests, probing, and imaging help localize the obstruction. Treatment targets restoring drainage or reducing tear production depending on the underlying etiology.