EXTERNAL FIXATION IN OPEN
TIBIAL FRACTURES-BEST
EVIDENCE
Hitesh Gopalan U
Clinical Asst Professor
www.orthoevidence.com
www.orthopaedicprinciples.com
Extensive Research
 Reamed Vs Unreamed
 External Fixation Vs Nailing

 Ex Fix followed by Delayed Nailing

 SPRINT trial, Tornetta et al.,, Bhandari et al.,
Petrisor et al., Schemitsch et al.,
Swiontkowski et al..Giannoudis et al..
External fixation in open tibial fractures best evidence
External Fixation
 3B
 Bone loss

 Extensive periosteal stripping
 Contamination
 Delayed Presentation
Meta analysis
 5 Randomised control trials comparing Ex Fix Vs Nailing
 Ex Fix Vs Nailing: no difference in deep infection rates

 The no of patients with type 3B injuries was low(eg.,

SPRINT Trial)

Bhandari M, Guyatt GH, Swiontkowski MF, Schemitsch EH: Treatment of open
fractures of the shaft of the tibia. J Bone Joint Surg Br 2001;83:62-68 LEVEL 2.
High Quality RCT
 Need for a high quality RCT that compares

nailing Vs external fixation in 3B fractures
Infection after IM nailing
 Catastrophe

 Multiple Surgeries
 Prolonged treatment
 Circular Fixator
Grading of Complications
Reoperation
 Dynamisation
 Bone Grafting
 Pin tract infections
 Treatment for an infected IM nail
Ciery and Mader
External Fixation
 Deep infection rates: 4-6%
 Loss of alignment
 Pin Tract Infections

 Union rates are similar with Nailing Vs Ex Fix
Giannoudis PV, Papakostidis C, Roberts C: A review of the management
of open fractures of the tibia and femur. J Bone Joint Surg Br
2006;88:281-289. LEVEL -3
Surgeon Choice

 Surgeons across North America
 Surgeons across India
Delayed Conversion
 Loss of alignment
 Shorter Duration of Ex fix

 Safe Interval(10-14 days)

Bhandari M, Zlowodzki M, Tornetta P III, Schmidt A, Templeman DC:
Intramedullary nailing following external fixation in femoral and
tibial shaft fractures. J OrthopTrauma 2005;19:140-144.
LEVEL- 2
Reamed nailing Vs Ex Fix

 Experimental data on thermal necrosis(Schemitsch et al..)

 Inflammatory mediator release(Il-6 and HLA DR release)-

correlates well with sepsis

Schemitsch EH, Kowalski MJ, Swiontkowski MF, Senft D: Cortical bone
blood flow in reamed and unreamed locked intramedullary nailing: A
fractured tibia model in sheep.
J OrthopTrauma 1994;8:373-382
Bone Loss
Delayed Presentation
 Delays in Debridement

 Delays in Antibiotic administration
 External fixation: repeat debridements
Infection
 External fixator

 Antibiotic loaded cement
 Conversion to a Ring fixator
External fixation in open tibial fractures best evidence
Infection after IM nail
 Removal of IM Nail

 ALBC
 Ring fixator: Excision and Bone transport
Evidence Cycle
Ask

Act

Acquire

Apply

Appraise

“EBM Begins and Ends with the Patient”
External fixation in open tibial fractures best evidence
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External fixation in open tibial fractures best evidence

  • 1. EXTERNAL FIXATION IN OPEN TIBIAL FRACTURES-BEST EVIDENCE Hitesh Gopalan U Clinical Asst Professor www.orthoevidence.com www.orthopaedicprinciples.com
  • 2. Extensive Research  Reamed Vs Unreamed  External Fixation Vs Nailing  Ex Fix followed by Delayed Nailing  SPRINT trial, Tornetta et al.,, Bhandari et al., Petrisor et al., Schemitsch et al., Swiontkowski et al..Giannoudis et al..
  • 4. External Fixation  3B  Bone loss  Extensive periosteal stripping  Contamination  Delayed Presentation
  • 5. Meta analysis  5 Randomised control trials comparing Ex Fix Vs Nailing  Ex Fix Vs Nailing: no difference in deep infection rates  The no of patients with type 3B injuries was low(eg., SPRINT Trial) Bhandari M, Guyatt GH, Swiontkowski MF, Schemitsch EH: Treatment of open fractures of the shaft of the tibia. J Bone Joint Surg Br 2001;83:62-68 LEVEL 2.
  • 6. High Quality RCT  Need for a high quality RCT that compares nailing Vs external fixation in 3B fractures
  • 7. Infection after IM nailing  Catastrophe  Multiple Surgeries  Prolonged treatment  Circular Fixator
  • 8. Grading of Complications Reoperation  Dynamisation  Bone Grafting  Pin tract infections  Treatment for an infected IM nail
  • 10. External Fixation  Deep infection rates: 4-6%  Loss of alignment  Pin Tract Infections  Union rates are similar with Nailing Vs Ex Fix Giannoudis PV, Papakostidis C, Roberts C: A review of the management of open fractures of the tibia and femur. J Bone Joint Surg Br 2006;88:281-289. LEVEL -3
  • 11. Surgeon Choice  Surgeons across North America  Surgeons across India
  • 12. Delayed Conversion  Loss of alignment  Shorter Duration of Ex fix  Safe Interval(10-14 days) Bhandari M, Zlowodzki M, Tornetta P III, Schmidt A, Templeman DC: Intramedullary nailing following external fixation in femoral and tibial shaft fractures. J OrthopTrauma 2005;19:140-144. LEVEL- 2
  • 13. Reamed nailing Vs Ex Fix  Experimental data on thermal necrosis(Schemitsch et al..)  Inflammatory mediator release(Il-6 and HLA DR release)- correlates well with sepsis Schemitsch EH, Kowalski MJ, Swiontkowski MF, Senft D: Cortical bone blood flow in reamed and unreamed locked intramedullary nailing: A fractured tibia model in sheep. J OrthopTrauma 1994;8:373-382
  • 15. Delayed Presentation  Delays in Debridement  Delays in Antibiotic administration  External fixation: repeat debridements
  • 16. Infection  External fixator  Antibiotic loaded cement  Conversion to a Ring fixator
  • 18. Infection after IM nail  Removal of IM Nail  ALBC  Ring fixator: Excision and Bone transport