This document introduces factorial research designs and multivariate analysis. It defines factorial designs as having two or more independent variables. A 2x2 factorial design is used as an example, examining the effects of initial diagnosis (general or social anxiety) and therapy type (group or individual) on client wellness. Key terms for factorial designs are defined, including cell means, marginal means, main effects, and interactions. Five patterns of factorial results are described: interactions where one simple effect is null while the other is significant; where simple effects are in opposite directions; where they are in the same direction but different sizes; and non-interactions where both simple effects are either significant and in the same direction/size or null. Main effects can sometimes be