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Failure to Thrive Shannon Pittman, M.D. University of Mississippi  Jackson, MS
 
 
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Objectives To define failure to thrive (FTT) To identify major classification of FTT  To discuss diagnostic workup of  FTT  To discuss treatment of FTT
Things We Will  Not  Cover Geriatric FTT Am Fam Physician. 2004 Jul 15;70(2):248, 257. Rehabil Nurs. 2005 Jul-Aug;30(4):152-9  Adolescent FTT
Things We Will  Not  Cover Other specific causes (e.g.) Congenital defects  Celiac disease HIV/AIDS Metabolic disorders CHF (reference for Jenny) Prog Pediatr Cardiol. 2000 Sep 1;11(3):195-202.
Why Do We Have to Talk About it at All? Personal Depending on current status in app. 9, 21, or 32 months you will sit for the ABFP (13%-pediatrics) ACGME competencies / AAFP core recommendations Patients Parental concerns Doc, is my baby growing right? Cognitive development Arch Dis Child. 2005 Sep;90(9):925-31. Epub 2005 May 12. J Child Psychol Psychiatry. 2004 Mar;45(3):641-54.
Clinical Vignette 15 month old admitted with lethargy from dermatology office Prior to admit, several days of decreased activity Med hx remarkable for eczema, treated with topical steroids
Clinical Vignette Wgt and ht both below 5 th  percentile, but had grown along the 25 th  percentile until age 4mo Extensive erythematous plaques on her back, diaper region, thighs, and polpliteal fossa bilaterally
Clinical Vignette What concerns you about this child What history questions should you ask What labs would you order How would you manage pt’s care
Okay, Tell Me What Happens Next - Afternoon clinic 10 Patients scheduled Everyone of them showed up Your 5 th  pt is new & has a typed list  It’s 4:00 and you are on pt 6 who happens to be a 9 mo well child
http://www.cha.state.md.us/edcp/html/immpg.html
We’re not alone In England, 54% of GP failed to diagnosis FTT Residency clinic, 41% with delayed dx Residency clinic, 29 dx, 100% dx incorrectly
FTT – Definition “Inadequate physical growth diagnosed by observation of growth over time using a standard growth chart”
Normal Growth Average wgt 7 lbs (3kg) Double by 4 months, triple by 12 Grow 25 cm in length during 1 st  year Make sure you have the right chart Premature Breastfeeding  www.cdc.gov/growthcharts
FTT Criteria Ht/Wgt less than 3 rd  to 5 th  percentile for age on >1 occasion Ht or Wgt falling 2 major percentiles Below 10 th  percentile for ht/wgt < 80% of ideal body wgt for age Head circumference important, but not part of FTT entity
FTT HISTORY !  HISTORY! HISTORY! Prenatal Feeding  # oz needed in 24 hours  Wgt (kgs) x 5  (need 100 kcal/kg/day) How formula prepared Good diet history (3 day journal) Bowel habits
FTT Physical Gomez Criteria <60 = severe; 61-75 = mod; 76-90 = mild Kwashiorkor – protein malnourishment Marasmus – caloric deficiency Short Stature Syndrome Constitutional Delay
FTT - Classification Organic FTT  Pre/postnatal Nonorganic FTT (NOFT) Pre/postnatal Mixed (25%)
FTT - Classification Organic FTT  Prenatal Causes Prematurity w/complications Toxic exposure Postnatal Inadequate intake Lack of appetite Inability to suck/swallow
FTT - Classification Organic, postnatal cont. Poor absorption and/or use of nutrients GI disorder (celiac, CF) Inborn errors of metabolism Increased metabolic demand Hyperthyroidism Chronic Disease
FTT - Classification Nonorganic Prenatal Malnourished mother ? Lack of prenatal bonding  Postnatal Poor feeding skills/disorder Dysfunctional family Difficult parent-child interactions Difficult Child Abuse/Neglect
 
Recap - Classification Failure to Thrive Organic Nonorganic Prenatal Postnatal Toxic Exposure Inborn errors Prenatal Postnatal Malnourished  mother Abuse/Neglect
FTT - Workup +/- Basic screening labs CBC, Chemistry, & UA Specific test directed by history HIV, ESR, TSH, Sweat chloride test, serum IGF-I, serum IgA/IgG antigliadin antibiodies X-rays for bone age
FTT – Treatment High calorie diet for catch up growth 150% of recommended daily caloric intake based on expected wgt +/- Feeding behavior modification Psychosocial involvement/ intervention Close follow up  Physical and cognitive delays Hospitalization when necessary
Clinical Vignette 15 month old admitted with lethargy from dermatology office Prior to admit, several days of decreased activity Med hx remarkable for eczema, treated with topical steroids
Clinical Vignette Wgt and ht both below 5 th  percentile, but had grown along the 25 th  percentile until age 4mo Extensive erythematous plaques on her back, diaper region, thighs, and polpliteal fossa bilaterally
Clinical Vignette What concerns you about this child What history questions should you ask What labs would you order How would you manage pt’s care
Summary: G.R.O.W.T.H. G ather history and extensive physical R emember genetic contribution O nly order basic labs in initial eval W onder about zebras T rack growth trends H ospitalize or hormonally treat
Take Home The keys to diagnosing FTT is finding the time to accurately measure and plot wgt/ht and then access the trend
http://www.cha.state.md.us/edcp/html/immpg.html Afternoon clinic 10 Patients scheduled Everyone of them showed up Your 5th pt is new & has a typed list  It’s 4:00 and you are on pt 6 who happens to be a 9 mo well child
Any Questions? www.child.com/.../ baby_babble.jsp
References Listernick, R. (2004). Accurate feeding history key to failure to thrive.  Pediatr Ann , 33:3, 161-9. Burgos, R., Jutte, D. (2000). Resident’s column: “doctor, is my child growing ok?”.  Pediatr Ann , 29:9, 585-7. Krugman, S., Dubowitz,H. (2003). Failure to thrive. American Fam Phy, 68:5, 879-84. Schwartz, R., Abegglen, J. (1996). Failure to thrive: an ambulatory approach.  Nurse Pract,  21:5, 19-31.  Careaga, M., Kernder, J. (200). A gastroenterologist’s approach to failure to thrive.  Pediatr Ann . 29:9, 558-67.  Bassali, R., Benjamin, J. (2004, August 11). Failure to Thrive.  eMedicine.  Retrieved September 17, 2005, from http:///www.emedicine.com/ped/topic738.htm.
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Failure To Thrive With Notes

  • 1. Failure to Thrive Shannon Pittman, M.D. University of Mississippi Jackson, MS
  • 2.  
  • 3.  
  • 8. Objectives To define failure to thrive (FTT) To identify major classification of FTT To discuss diagnostic workup of FTT To discuss treatment of FTT
  • 9. Things We Will Not Cover Geriatric FTT Am Fam Physician. 2004 Jul 15;70(2):248, 257. Rehabil Nurs. 2005 Jul-Aug;30(4):152-9 Adolescent FTT
  • 10. Things We Will Not Cover Other specific causes (e.g.) Congenital defects Celiac disease HIV/AIDS Metabolic disorders CHF (reference for Jenny) Prog Pediatr Cardiol. 2000 Sep 1;11(3):195-202.
  • 11. Why Do We Have to Talk About it at All? Personal Depending on current status in app. 9, 21, or 32 months you will sit for the ABFP (13%-pediatrics) ACGME competencies / AAFP core recommendations Patients Parental concerns Doc, is my baby growing right? Cognitive development Arch Dis Child. 2005 Sep;90(9):925-31. Epub 2005 May 12. J Child Psychol Psychiatry. 2004 Mar;45(3):641-54.
  • 12. Clinical Vignette 15 month old admitted with lethargy from dermatology office Prior to admit, several days of decreased activity Med hx remarkable for eczema, treated with topical steroids
  • 13. Clinical Vignette Wgt and ht both below 5 th percentile, but had grown along the 25 th percentile until age 4mo Extensive erythematous plaques on her back, diaper region, thighs, and polpliteal fossa bilaterally
  • 14. Clinical Vignette What concerns you about this child What history questions should you ask What labs would you order How would you manage pt’s care
  • 15. Okay, Tell Me What Happens Next - Afternoon clinic 10 Patients scheduled Everyone of them showed up Your 5 th pt is new & has a typed list It’s 4:00 and you are on pt 6 who happens to be a 9 mo well child
  • 17. We’re not alone In England, 54% of GP failed to diagnosis FTT Residency clinic, 41% with delayed dx Residency clinic, 29 dx, 100% dx incorrectly
  • 18. FTT – Definition “Inadequate physical growth diagnosed by observation of growth over time using a standard growth chart”
  • 19. Normal Growth Average wgt 7 lbs (3kg) Double by 4 months, triple by 12 Grow 25 cm in length during 1 st year Make sure you have the right chart Premature Breastfeeding www.cdc.gov/growthcharts
  • 20. FTT Criteria Ht/Wgt less than 3 rd to 5 th percentile for age on >1 occasion Ht or Wgt falling 2 major percentiles Below 10 th percentile for ht/wgt < 80% of ideal body wgt for age Head circumference important, but not part of FTT entity
  • 21. FTT HISTORY ! HISTORY! HISTORY! Prenatal Feeding # oz needed in 24 hours Wgt (kgs) x 5 (need 100 kcal/kg/day) How formula prepared Good diet history (3 day journal) Bowel habits
  • 22. FTT Physical Gomez Criteria <60 = severe; 61-75 = mod; 76-90 = mild Kwashiorkor – protein malnourishment Marasmus – caloric deficiency Short Stature Syndrome Constitutional Delay
  • 23. FTT - Classification Organic FTT Pre/postnatal Nonorganic FTT (NOFT) Pre/postnatal Mixed (25%)
  • 24. FTT - Classification Organic FTT Prenatal Causes Prematurity w/complications Toxic exposure Postnatal Inadequate intake Lack of appetite Inability to suck/swallow
  • 25. FTT - Classification Organic, postnatal cont. Poor absorption and/or use of nutrients GI disorder (celiac, CF) Inborn errors of metabolism Increased metabolic demand Hyperthyroidism Chronic Disease
  • 26. FTT - Classification Nonorganic Prenatal Malnourished mother ? Lack of prenatal bonding Postnatal Poor feeding skills/disorder Dysfunctional family Difficult parent-child interactions Difficult Child Abuse/Neglect
  • 27.  
  • 28. Recap - Classification Failure to Thrive Organic Nonorganic Prenatal Postnatal Toxic Exposure Inborn errors Prenatal Postnatal Malnourished mother Abuse/Neglect
  • 29. FTT - Workup +/- Basic screening labs CBC, Chemistry, & UA Specific test directed by history HIV, ESR, TSH, Sweat chloride test, serum IGF-I, serum IgA/IgG antigliadin antibiodies X-rays for bone age
  • 30. FTT – Treatment High calorie diet for catch up growth 150% of recommended daily caloric intake based on expected wgt +/- Feeding behavior modification Psychosocial involvement/ intervention Close follow up Physical and cognitive delays Hospitalization when necessary
  • 31. Clinical Vignette 15 month old admitted with lethargy from dermatology office Prior to admit, several days of decreased activity Med hx remarkable for eczema, treated with topical steroids
  • 32. Clinical Vignette Wgt and ht both below 5 th percentile, but had grown along the 25 th percentile until age 4mo Extensive erythematous plaques on her back, diaper region, thighs, and polpliteal fossa bilaterally
  • 33. Clinical Vignette What concerns you about this child What history questions should you ask What labs would you order How would you manage pt’s care
  • 34. Summary: G.R.O.W.T.H. G ather history and extensive physical R emember genetic contribution O nly order basic labs in initial eval W onder about zebras T rack growth trends H ospitalize or hormonally treat
  • 35. Take Home The keys to diagnosing FTT is finding the time to accurately measure and plot wgt/ht and then access the trend
  • 36. http://www.cha.state.md.us/edcp/html/immpg.html Afternoon clinic 10 Patients scheduled Everyone of them showed up Your 5th pt is new & has a typed list It’s 4:00 and you are on pt 6 who happens to be a 9 mo well child
  • 38. References Listernick, R. (2004). Accurate feeding history key to failure to thrive. Pediatr Ann , 33:3, 161-9. Burgos, R., Jutte, D. (2000). Resident’s column: “doctor, is my child growing ok?”. Pediatr Ann , 29:9, 585-7. Krugman, S., Dubowitz,H. (2003). Failure to thrive. American Fam Phy, 68:5, 879-84. Schwartz, R., Abegglen, J. (1996). Failure to thrive: an ambulatory approach. Nurse Pract, 21:5, 19-31. Careaga, M., Kernder, J. (200). A gastroenterologist’s approach to failure to thrive. Pediatr Ann . 29:9, 558-67. Bassali, R., Benjamin, J. (2004, August 11). Failure to Thrive. eMedicine. Retrieved September 17, 2005, from http:///www.emedicine.com/ped/topic738.htm.
  • 39. Thanks for Your Attention! www.jade-designs.org/ tubetotin/jababybottom.gif