2. Introduction:
It is a specialized loose non-
mineralised vascularised
connective tissue
Responsible for the formation
of dentine.
Contained within pulp chamber
and root canal of the tooth.
Remains active through out
life.
3. Every person normally has a total of 52 pulp
organs, 32 in the permanent 20 in the
primary dentition .
The total volumes of all the permanent teeth
pulp organs is 0.38 cc.
The apical foramen is the opening from the
pulp at the apex of the tooth which is to be
continuous with the periapical tissue
4. The average size of apical foramen of the maxillary
teeth in the adult is 0.4 mm.
In the mandibular teeth it is slightly smaller with 0.3
mm in diameter.
ACCESSORY CANALS
Found in apical third region
furcation region.
5. Anatomy of Pulp -:
Pulp horns or Cornua
Pulp Chamber Coronal
Pulp
Accessory Canal or Lateral
Canals
Apical Foramen
Root Canals Radicular Pulp
6. PRIMARY PULP ORGANS
Primary pulp undergoes development in the oral
cavity for about 8.3 years which can be divided into
three periods :-
Pulp organ growth time during crown root are
developing
Pulp maturation from root formation till start of root
resorption
Pulp regression from root resorption to tooth exfoliation
7. Pulp of the permanent teeth undergoes
development for about 1
2 years and 4 months.
The maxillary arch pulp organs require slightly more
time to complete each process of development
than do the mandibular arches.
PERMANENT PULP ORGANS
8. Pulpogenesis-:
The development of pulp is similar to dentin as both are
derived from the dental papilla.
Proliferating Dental papilla invaginates and encloses the
Enamel organ.
Cells of dental papillae appear as undifferentiated
mesenchymal cells differentiate into stellate shaped
ļ¬broblasts.
Odontoblasts differentiation starts from the peripheral cells
of dental papillae dentine formation starts Inner enamel
epithelium is stimulated IEE cells differentiates into
Ameloblasts Enamel is laid down.
9. Dental papilla Pulp Organ
Nerve terminals appear in the dental follicle
in 1
1
th
week of intrauterine life 1
8
th
week in
dental papilla 24
th
week in
subodontoblastic region after formation of 1
st
layer of enamel dentin
10. Increase in the nerve ļ¬bres neurovascular bundles
in central portion of the pulp
Nerve myelination starts in few large nerves of pulp
when dentin formation is in progress about to
ļ¬nish
Finally, nerves reach odontogenic zone of pulp
11. The dental pulp occupies center of each tooth and
consists of soft connective tissue.
Pulp is divided into :-
Coronal Pulp - located centrally in the crowns of
teeth
Radicular Pulp - located in the root portion
12. CORONAL PULP
It has pulp horns, which are
protrusions that extend into the
cusps of each tooth.
The number of these horns thus
depends on the number of cusps.
13. The cervical region of the pulp
organs constricts follows the
contour of the crown and at this
zone the coronal pulp joins the
radicular pulp.
14. RADICULAR PULP
The radicular pulp is that pulp
extending from the cervical region of
the crown to the root apex.
In the anterior teeth the radicular
pulp are single and in posterior teeth
are multiple.
15. They are not always straight and
vary in size, shape and number.
The radicular portion of the pulp
organ is continuous with the
periapical connective tissue through
apical foramen.
16. APICAL FORAMEN
Average size of apical foramen of the
maxillary teeth in the adult is 0.4mm in
diameter.
In the mandibular teeth it is slightly smaller
being 0.3mm in diameter.
The location and shape of the apical
foramen may undergo change as a result of
functional inļ¬uence on the teeth.
17. Histological structure of the
pulp
Cells Intercellular
substance
Blood vessels, Lymph
vessels, Nerves
FIBRES
Collagen I III
Elastic ļ¬bres
(B.V walls)
GROUND SUSBSTANCE
Glycosaminoglycans
Glycoproteins
18. STRUCTURAL FEATURES
The central region of both coronal
and radicular pulp contains large
nerve trunks and blood vessels and
is termed as Pulp Core.
19. Peripherally , pulp is circumscribed by the
specialized odontogenic region composed
of-:
1
) The Odontoblast
2) Cell free zone (Zone of Weil)
3) Cell rich zone
4) Pulpal Core
22. INTERCELLULAR SUBSTANCES
The intercellular substance is dense, and
gel like in nature, varies in appearance
from ļ¬nely granular to ļ¬brillar and
appears denser in some areas.
23. Composed of glycosaminoglycans and proteoglycans.
The ground substance lends support to the cells of the
pulp while it also serves as a means for transport of
nutrients from the blood vessels to the cells, as well as
for transport of metabolites from cells to blood vessels.
24. FIBROBLAST
The pulp organ consist of specialized
connective tissue and lacks elastic ļ¬bers .
Fibroblasts are the most numerous cell
type in the pulp.
25. Help in collagen ļ¬ber formation through the
entire pulp during the life of the tooth.
They have typical stellate shape and
extensive processes that contact and are
joined by intercellular junctions to the
processes of another ļ¬broblast.
26. Microscopically the ļ¬broblast nuclei stain
deeply with basic dyes and their
cytoplasm is lighter stained and appears
homogenous.
Electron microscope reveal abundant
rough surfaced endoplasmic reticulum,
mitochondria, and other organelles in
the cytoplasm.
27. This indicates these cells are active
in pulpal collagen production.
In older pulp these ļ¬broblast appear
rounded, or spindle shaped with
short processes and exhibit fewer
intracellular organelles, they are then
termed as FIBROCYTES.
28. In addition to forming the pulp matrix,
they also have capability of ingesting
and degrading this same matrix.
These cells thus have a dual function
with pathways for both synthesis and
degradation in the same cell.
29. FIBRES
The collagen ļ¬bers in the pulp exhibit typical
cross striations at 64nm and range in length
from 1
0 to 1
00 nm or more.
Bundles of these ļ¬bers appears throughout
the pulp.
30. After root completion the pulp matures
and bundles of collagen ļ¬bers increase in
number.
They may appear scattered throughout
the coronal or radicular pulp, or they may
appear in bundles and are termed as
DIFFUSE or BUNDLE COLLAGEN.
31. UNDIFFERENTIATED MESENCHYMAL CELLS
These cells are the primary cells in very
young pulp, but a few are seen in the pulp
after root completion.
They appear larger then ļ¬broblast and are
polyhedral in shape with peripheral
processes and large oval staining nuclei.
32. They are found along pulp vessels, in
the cell rich zone and scattered
throughout the central pulp.
They are believed to be totipotent
cells and when need arises they can
become Odontoblast ,ļ¬broblasts or
macrophages.
33. ODONTOBLAST
They are the second most prominent
cell in the pulp, reside adjacent to the
predentine with cell bodies in the pulp
and cell processes in the dentinal
tubules.
They are approximately 5 to7µm in
diameter and 25 to 40mu m in length.
34. They have a constant location, that
is in the āOdontogenic zone of the
pulpā.
The cell bodies of the odontoblasts
are columnar in appearance with
large oval nuclei, which ļ¬ll the basal
part of the cell.
35. Immediately adjacent to the nucleus basally
is rough endoplasmic reticulum and golgi
apparatus.
The cells in the odontoblastic row lie very
close to each other, and the plasma
membranes of adjacent cells exhibit
junctional complexes.
Towards the apex of the cell appears an
abundance of rough endoplasmic reticulum.
36. DEFENSE CELLS
In addition to ļ¬broblasts,
odontoblasts, and the cells that are a
part of the neural and vascular
systems of the pulp, there are cells
important to the defense of the pulp.
37. These are -:
1
) Histiocytes or Macrophages
2) Mast cells
3) Plasma cells
In addition there are blood vascular elements
such as
neutrophils (PMN), eosinophil, basophils,
lymphocytes
monocytes.
These latter cells migrate from the pulpal blood
vessels and develop in response to inļ¬ammation.
38. BLOOD VESSELS
The pulp organ is extensively
vascularized.
The blood vessels of both the pulp
periodontium arise from the inferior or
superior alveolar artery also drain by
the same veins in both the mandibular
maxillary regions.
39. Although branches of the alveolar
arteries supply both the tooth and
its supporting tissues, those entering
the pulp are different in structure
from the branches to the
periodontium.
40. As vessels enter the tooth their walls
become considerably thinner than
those surrounding the tooth.
Small arteries and arterioles enter
the apical canal and pursue a direct
route to the coronal pulp.
41. Along their course they give off
numerous branches in the
radicular pulp that pass
peripherally to form a plexus in
the odontogenic region.
42. Pulpal blood ļ¬ow is more rapid than
in most areas of the body.
Veins and venules that are larger
than the arteries also appear in the
central region of the root pulp.
43. LYMPH VESSELS
Lymph capillaries are endothelium-
lined tubes that join thin-walled
lymph venules or veins in the central
pulp.
Lymph vessels draining the pulp and
periodontal ligament have a
common outlet.
44. Those draining the anterior teeth
pass to the submental lymph
nodes; those of the posterior
teeth pass to the submandibular
and deep cervical lymph nodes.
45. NERVES
The abundant nerve supply in the
pulp follows the distribution of the
blood vessels.
The majority of the nerves that
enter the pulp are nonmyelinated.
46. The nonmyelinated nerves are found
in close association with the blood
vessels of the pulp and many are
sympathetic in nature.
Thick nerve bundles enter the apical
foramen and proceed to the coronal
area where their ļ¬bers separate and
radiate peripherally to the
odontogenic zone.
47. The peripheral axons form a network
of nerves located adjacent to the cell-
rich zone.
This is termed as the Parietal layer of
nerves, also known as Plexus of
Rashkow.
48. Most of the nerve endings
located among the
odontoblasts are sensory
receptors.
49. Sensory response in the pulp cannot
differentiate between heat, touch,
pressure, or chemicals .
This is because the pulp organs lack
those types of receptors that
speciļ¬cally distinguish these other
stimuli.
51. INDUCTIVE :-
The ļ¬rst role of the pulp is to induce
oral epithelial differentiation into
dental lamina and enamel organ
formation.
The pulp anlage also induces the
developing enamel organ to become
a particular type of tooth.
52. FORMATIVE :-
The pulp organ cells produce the
dentin that surrounds and protects
the pulp.
The pulpal odontoblasts develop the
organic matrix and function in its
calciļ¬cation.
53. NUTRITIVE :- The pulp nourishes the
dentin through the odontoblasts and
their processes and by means of the
blood vascular system of the pulp.
PROTECTIVE :- The sensory nerves in the
tooth respond with pain to all stimuli
such as heat, cold, pressure, operative
cutting procedures, and chemical agents.
54. DEFENSIVE OR REPARATIVE:-
The pulp is an organ with remarkable
reparative abilities.
It responds to irritation, whether
mechanical, thermal, chemical, or
bacterial, by producing reparative
dentin and mineralizing any affected
dentinal tubules.
55. DEVELPOMENT
The tooth pulp is initially called the
dental papilla. This tissue is
designated as āpulpā only after
dentin forms around it.
The development of the dental pulp
begins at about the eighth week of
embryonic life in the human.
56. As this occurs, the tissue is no
longer called dental papilla but is
now designated the pulp organ.
58. CELL CHANGES
In addition to the appearance of
fewer cells in the aging pulp, the
cells are characterized by a decrease
in size and number of cytoplasmic
organelles.
The ļ¬broblasts in the aging pulp
exhibit less perinuclear cytoplasm
and possess long, thin cytoplasmic
59. PULP STONES OR DENTICLES
Pulp stones, or denticles , are
nodular, calciļ¬ed masses appearing
in either or both the coronal or root
portions of the pulp organ.
They develop in teeth that appear
normal in other aspects.
61. Pulp stone are classiļ¬ed as :-
I.According to their structure
a) True denticles
b) False denticles
c) Diffuse calciļ¬cations
II. According to their location :-
a) Free
b) Attached
c) Embedded
62. TRUE DENTICLES
The structure is similar to dentin in
that they exhibit dentinal tubuli
containing the processes of the
odontoblast that formed them.
True denticles are rare and are
usually located close to the apical
foramen.
63. FALSE DENTICLES
They do not exhibit dentinal tubules
but appear instead as concentric
layers of calciļ¬ed tissue.
All denticles begins as small nodules
but increase in size by incremental
growth on their surface.
65. DIFFUSE CALCIFICATIONS
It appear as irregular calciļ¬c deposits
in the pulp tissue, usually following
collagenous ļ¬bers bundles or blood
vessels.
Sometime they develop into larger
masses but usually persist as ļ¬ne
calciļ¬ed spicules.
66. Diffuse calciļ¬cation are usually
found in the root canal and less
often in the coronal area,
whereas denticles are seen more
frequently in the coronal pulp.
67. II. According to the location:
Free denticles are entirely
surrounded by pulp tissue.
Attached denticles are
partly fused with the
dentin.
68. Embedded denticles are
entirely surrounded by dentin.
All are formed free in the pulp
and later become attached or
embedded as dentin formation
progresses.
69. The incidence as well as size of
pulp stones increases with age.
66% 1
0 to 30 years of age
80% 30 to 50 years of age
90% over 50 years of age