Luke Ross outlines several potential technical and practical problems that could arise during the production of his short film project. Some key issues discussed include equipment malfunctions like problems with the camera's aperture or SD card, broken camera components, unstable tripods, and dead batteries in audio recorders. Other challenges involve props and costumes not arriving as expected, unwanted noise interfering with audio, unreliable actors/locations, and tight timelines. Luke proposes solutions such as having backup equipment, recording audio separately, securing alternative options, and creating thorough schedules and safety plans to mitigate risks.