The document summarizes key points about implementing a new Great Lakes Water Quality Agreement between the US and Canada. It discusses the vision of a healthy Great Lakes that benefits both current and future generations. It also outlines several approaches the agreement takes, such as the "polluter pays" principle. Specific annexes on issues like chemicals, nutrients, invasive species, and climate change are also summarized. The role of science, monitoring, and domestic policy priorities to achieve the agreement's goals are discussed.