Guide quit smoking

Guide to Quitting Smoking
What do I need to know about quitting?
The US Surgeon General has said, “Smoking cessation [stopping smoking] represents the
single most important step that smokers can take to enhance the length and quality of
their lives.”
It’s hard to quit smoking, but you can do it. To have the best chance of quitting and
staying a non-smoker, you need to know what you’re up against, what your options are,
and where to go for help. You’ll find this information here.
Why is it so hard to quit smoking?
Mark Twain said, “Quitting smoking is easy. I’ve done it a thousand times.” Maybe
you’ve tried to quit, too. Why is quitting and staying quit hard for so many people? The
answer is nicotine.
Nicotine
Nicotine is a drug found naturally in tobacco. It’s as addictive as heroin or cocaine. Over
time, a person becomes physically dependent on and emotionally addicted to nicotine.
This physical dependence causes unpleasant withdrawal symptoms when you try to quit.
The emotional and mental dependence (addiction) make it hard to stay away from
nicotine after you quit. Studies have shown that to quit and stay quit smokers must deal
with both the physical and mental dependence.
How nicotine gets in, where it goes, and how long it stays
When you inhale smoke, nicotine is carried deep into your lungs. There it’s quickly
absorbed into the bloodstream and carried throughout your body. In fact, nicotine inhaled
in cigarette smoke reaches the brain faster than drugs that enter the body through a vein
(intravenously or IV).
Nicotine affects many parts of your body, including your heart and blood vessels, your
hormones, the way your body uses food (your metabolism), and your brain. Nicotine can

be found in breast milk and even in the cervical mucus of a female smoker. During
pregnancy, nicotine crosses the placenta and has been found in amniotic fluid and the
umbilical cord blood of newborn infants.
Different factors affect how long it takes the body to remove nicotine and its by-products.
In most cases, regular smokers will still have nicotine or its by-products, such as cotinine,
in their bodies for about 3 to 4 days after stopping.
How nicotine hooks smokers
Nicotine causes pleasant feelings and distracts the smoker from unpleasant feelings. This
makes the smoker want to smoke again. Nicotine also acts as a kind of depressant by
interfering with the flow of information between nerve cells. Smokers tend to smoke
more cigarettes as the nervous system adapts to nicotine. This, in turn, increases the
amount of nicotine in the smoker’s blood.
Over time, the smoker develops a tolerance to nicotine. Tolerance means that it takes
more nicotine to get the same effect that the smoker used to get from smaller amounts.
This leads to an increase in smoking. At some point, the smoker reaches a certain
nicotine level and then keeps smoking to keep the level of nicotine within a comfortable
range.
When a person finishes a cigarette, the nicotine level in the body starts to drop, going
lower and lower. The pleasant feelings wear off, and the smoker notices wanting a
smoke. If smoking is postponed, the smoker may start to feel irritated and edgy. Usually
it doesn’t reach the point of real withdrawal symptoms, but the smoker gets more
uncomfortable over time. When the person smokes a cigarette, the unpleasant feelings
fade, and the cycle continues.
Nicotine withdrawal symptoms can lead quitters back to smoking
When smokers try to cut back or quit, the lack of nicotine leads to withdrawal symptoms.
Withdrawal is both physical and mental. Physically, the body reacts to the absence of
nicotine. Mentally, the smoker is faced with giving up a habit, which calls for a major
change in behavior. Both the physical and mental factors must be addressed for the
quitting process to work.
Those who have smoked regularly for a few weeks or longer will have withdrawal
symptoms if they suddenly stop using tobacco or greatly reduce the amount they smoke.
Symptoms usually start within a few hours of the last cigarette and peak about 2 to 3 days
later when most of the nicotine and its by-products are out of the body. Withdrawal
symptoms can last for a few days to up to several weeks. They will get better every day
that you stay smoke-free.
Withdrawal symptoms can include any of the following:
• Dizziness (which may only last 1 to 2 days after quitting)
• Depression

• Feelings of frustration, impatience, and anger
• Anxiety
• Irritability
• Sleep disturbances, including having trouble falling asleep and staying asleep, and
having bad dreams or even nightmares
• Trouble concentrating
• Restlessness or boredom
• Headaches
• Tiredness
• Increased appetite
• Weight gain
• Constipation and gas
• Cough, dry mouth, sore throat, and nasal drip
• Chest tightness
• Slower heart rate
These symptoms can make the smoker start smoking again to boost blood levels of
nicotine until the symptoms go away. (For information on coping with withdrawal, see
the section called “How to quit.”)
Other substances in cigarette smoke
There is some evidence that other chemicals in cigarette smoke may act with nicotine to
make it harder to quit smoking. The effects of smoking on monoamine oxidase (a brain
chemical) and the substances called harman and norharman are still being studied. For
some people, withdrawing from smoking causes more severe mood problems, which can
result in worse cravings and more trouble staying quit.
Smoking affects other medicines
Smoking also makes your body get rid of some drugs faster than usual. When you quit
smoking, it may change the levels of these drugs. Though it’s not truly withdrawal, this
change can cause problems and add to the discomfort of quitting. Ask your doctor if any
medicines you take need to be checked or changed after you quit.

Why should I quit?
Your health
Health concerns usually top the list of reasons people give for quitting smoking. This is a
very real concern: smoking harms nearly every organ of the body.
Half of all smokers who keep smoking will end up dying from a smoking-related illness.
In the United States alone, smoking is responsible for nearly 1 in 5 deaths, and about 8.6
million people suffer from smoking-related lung and heart diseases.
Cancer
Nearly everyone knows that smoking can cause lung cancer, but few people realize it is
also linked to a higher risk for many other kinds of cancer too, including cancer of the
mouth, nose, sinuses, lip, voice box (larynx), throat (pharynx), esophagus, bladder,
kidney, pancreas, ovary, cervix, stomach, colon, rectum, and acute myeloid leukemia.
Lung diseases
Smoking greatly increases your risk of getting long-term lung diseases like emphysema
and chronic bronchitis. These diseases make it harder to breathe, and are grouped
together under the name chronic obstructive pulmonary disease (COPD). COPD causes
chronic illness and disability, and gets worse over time — sometimes becoming fatal.
Emphysema and chronic bronchitis can be found in people as young as 40, but are
usually found later in life, when the symptoms become much worse. Long-term smokers
have the highest risk of developing severe COPD. Pneumonia is also included in the list
of diseases caused or made worse by smoking.
Heart attacks, strokes, and blood vessel diseases
Smokers are twice as likely to die from heart attacks as non-smokers. Smoking is a major
risk factor for peripheral vascular disease, a narrowing of the blood vessels that carry
blood to the leg and arm muscles. Smoking also affects the walls of the vessels that carry
blood to the brain (carotid arteries), which can cause strokes. Smoking can cause
abdominal aortic aneurysm, in which the layered walls of the body’s main artery (the
aorta) weaken and separate, often causing sudden death. And men who smoke are more
likely to develop erectile dysfunction (impotence) because of blood vessel disease.
Blindness and other problems
Smoking increases the risk of macular degeneration, one of the most common causes of
blindness in older people. It promotes cataracts, which cloud the lens of the eye. It also
causes premature wrinkling of the skin, bad breath, gum disease, tooth loss, bad-smelling
clothes and hair, and yellow teeth and fingernails.

Special risks to women and babies
Women have some unique risks linked to smoking. Women over 35 who smoke and use
birth control pills have a higher risk of heart attack, stroke, and blood clots in the legs.
Women who smoke are more likely to miscarry (lose the baby) or have a lower birth-
weight baby. Low birth-weight babies are more likely to die or have learning and
physical problems.
Years of life lost due to smoking
Based on data collected in the late 1990s, the US Centers for Disease Control and
Prevention (CDC) estimated that adult male smokers lost an average of 13.2 years of life
and female smokers lost 14.5 years of life because of smoking.
Each year, smoking causes early deaths of about 443,000 people in the United States.
And given the diseases that smoking can cause, it can steal your quality of life long
before you die. Smoking-related illness can limit your activities by making it harder to
breathe, get around, work, or play.
Why quit now?
No matter how old you are or how long you’ve smoked, quitting can help you live longer
and be healthier. People who stop smoking before age 50 cut their risk of dying in the
next 15 years in half compared with those who keep smoking. Ex-smokers enjoy a higher
quality of life. They have fewer illnesses like colds and the flu, lower rates of bronchitis
and pneumonia, and feel healthier than people who still smoke.
For decades the Surgeon General has reported the health risks linked to smoking. In
1990, the Surgeon General concluded:
• Quitting smoking has major and immediate health benefits for men and women of all
ages. These benefits apply to people who already have smoking-related diseases and
those who don’t.
• Ex-smokers live longer than people who keep smoking.
• Quitting smoking lowers the risk of lung cancer, other cancers, heart attack, stroke,
and chronic lung disease.
• Women who stop smoking before pregnancy or during the first 3 to 4 months of
pregnancy reduce their risk of having a low birth-weight baby to that of women who
never smoked.
• The health benefits of quitting smoking are far greater than any risks from the small
weight gain (usually less than 10 pounds) or any emotional or psychological problems
that may follow quitting.

When smokers quit — what are the benefits over time?
20 minutes after quitting
Your heart rate and blood pressure drop.
(Effect of smoking on arterial stiffness and pulse pressure amplification, Mahmud
A, Feely J. Hypertension. 2003:41:183)
12 hours after quitting
The carbon monoxide level in your blood drops to normal.
(US Surgeon General’s Report, 1988, p. 202)
2 weeks to 3 months after quitting
Your circulation improves and your lung function increases.
(US Surgeon General’s Report, 1990, pp.193, 194,196, 285, 323)
1 to 9 months after quitting
Coughing and shortness of breath decrease; cilia (tiny hair-like structures that move
mucus out of the lungs) start to regain normal function in the lungs, increasing the ability
to handle mucus, clean the lungs, and reduce the risk of infection.
(US Surgeon General’s Report, 1990, pp. 285-287, 304)
1 year after quitting
The excess risk of coronary heart disease is half that of a continuing smoker’s.
(US Surgeon General’s Report, 2010, p. 359)
5 years after quitting
Risk of cancer of the mouth, throat, esophagus, and bladder are cut in half. Cervical
cancer risk falls to that of a non-smoker. Stroke risk can fall to that of a non-smoker after
2-5 years.
(A Report of the Surgeon General: How Tobacco Smoke Causes Disease - The
Biology and Behavioral Basis for Smoking-Attributable Disease Fact Sheet, 2010;
and Tobacco Control: Reversal of Risk After Quitting Smoking. IARC Handbooks
of Cancer Prevention, Vol. 11. 2007, p 341)
The risk of dying from lung cancer is about half that of a person who is still smoking.
The risk of cancer of the larynx (voice box) and pancreas decreases.

(A Report of the Surgeon General: How Tobacco Smoke Causes Disease - The
Biology and Behavioral Basis for Smoking-Attributable Disease Fact Sheet, 2010;
and US Surgeon General’s Report, 1990, pp. vi, 155, 165)
The risk of coronary heart disease is that of a non-smoker’s.
(Tobacco Control: Reversal of Risk After Quitting Smoking. IARC Handbooks of
Cancer Prevention, Vol. 11. 2007. p 11)
These are just a few of the benefits of quitting smoking for good. Quitting smoking
lowers the risk of diabetes, lets blood vessels work better, and helps the heart and lungs.
Quitting while you are younger will reduce your health risks more, but quitting at any age
can give back years of life that would be lost by continuing to smoke.
Immediate rewards of quitting
Kicking the tobacco habit offers some benefits that you’ll notice right away and some
that will develop over time. These rewards improve most peoples’ day-to-day lives a
great deal:
• Breath smells better
• Stained teeth get whiter
• Bad smelling clothes and hair go away
• Yellow fingers and fingernails disappear
• Food tastes better
• Sense of smell returns to normal
• Everyday activities (such as climbing stairs or light housework) no longer leave them
out of breath
• You can be in smoke-free buildings without having to go outside to smoke.
Cost
The prospect of better health is a major reason for quitting, but there are other reasons,
too.
Smoking is expensive. It isn’t hard to figure out how much you spend on smoking:
multiply how much money you spend on tobacco every day by 365 (days per year). The
amount may surprise you. Now multiply that by the number of years you have been using
tobacco and that amount will probably shock you.

Multiply the cost per year by 10 (for the next 10 years) and ask yourself what you would
rather do with that much money.
And this doesn’t include other possible costs, such as higher costs for health and life
insurance, and likely health care costs due to tobacco-related problems.
Social acceptance
Smoking is less socially acceptable now than ever.
Today, almost all workplaces have some type of smoking rules. Some employers even
prefer to hire non-smokers. Studies show smoking employees cost businesses more
because they are out sick more. Employees who are ill more often than others can raise
an employer’s need for costly short-term replacement workers. They can increase
insurance costs for other employees and for the employer, who often pays part of the
workers’ insurance premiums. Smokers in a building also can increase the maintenance
costs of keeping odors down, since residue from cigarette smoke gets into to carpets,
drapes, and other fabrics.
Smoking in banned in most public elementary and secondary school buildings and, in
many states it’s banned on school campuses. It’s common for colleges and universities to
have no-smoking policies for all campus buildings, including residential housing. And
some are moving toward smoke-free campuses, too.
Landlords may choose not to rent to smokers since maintenance costs and insurance rates
may go up when smokers live in buildings.
Friends may ask you not to smoke in their homes or cars. Public buildings, concerts, and
even sporting events are largely smoke-free. And more and more communities are
restricting smoking in all public places, including restaurants and bars. Like it or not,
finding a place to smoke can be a hassle.
Smokers may also find their prospects for dating or romantic involvement, including
marriage, are largely limited to other smokers. Cigarette smokers now make up about
19% of the adult population.
Health of others
Smoking not only harms your health but it hurts the health of those around you. Exposure
to secondhand smoke (also called environmental tobacco smoke or passive smoking)
includes exhaled smoke as well as smoke from burning cigarettes.
Studies have shown that secondhand smoke causes thousands of deaths each year from
lung cancer in healthy non-smokers.
If a mother smokes, there is a higher risk of her baby developing asthma in childhood,
especially if she smoked while she was pregnant. Women who smoke during pregnancy
are more likely to have low-birth weight infants.

Babies and children raised in a household where there is smoking have more ear
infections, colds, bronchitis, and problems with breathing than children in non-smoking
families. Secondhand smoke is linked to sudden infant death syndrome (SIDS) and slow
lung growth in children. Secondhand smoke can also cause eye irritation, headaches,
nausea, and dizziness.
Setting an example
If you have children, you probably want to set a good example for them. When asked,
nearly all smokers say they don’t want their children to smoke. But children whose
parents smoke are more likely to start smoking themselves. You can become a better role
model for them by quitting now.
Help with the mental part of addiction
Smokers have more tools than ever to help them quit smoking for good — there’s a wide
range of counseling services, self-help materials, and medicines available.
Some people are able to quit on their own, without the help of others or the use of
medicines. But for many smokers, it can be hard to break the social and emotional ties to
smoking while getting over nicotine withdrawal symptoms at the same time. Fortunately,
there are many sources of support out there.
Telephone-based help to stop smoking
All 50 states and the District of Columbia run some type of free, telephone-based
program that links callers with trained counselors. These specialists help plan a quit
method that fits each person’s unique smoking pattern. People who use telephone
counseling have twice the success rate in quitting smoking as those who don’t get this
type of help. Help from a counselor can keep quitters from making many common
mistakes.
Telephone counseling is also easier to use than some other support programs. It doesn’t
require driving, transportation, or child care, and it’s available nights and weekends.
Counselors may suggest a combination of methods including medicines, local classes,
self-help brochures, and/or a network of family and friends.
Call us to get help finding a phone counseling program in your area.
Quit-smoking programs and support groups
Members of support groups for quitters can be helpful, too. One long-standing peer help
program is Nicotine Anonymous®
, an open support group that offers a way to find others
who are quitting tobacco and living smoke-free. It also offers a long-term approach to

quitting. (See the “To learn more” section for contact information.) But this is only one of
many types of support programs.
Some workplaces, hospitals, and wellness centers have stop-smoking programs, groups,
or classes. They may be led by professionals and focus on information and education, or
they may be run by volunteers. Some programs may be set up like classes, while others
focus on sharing by members of the group.
For people who cannot go to support group meetings, there are online support systems as
well as phone-based support (discussed above). Check with your employer, health
insurance company, or local hospital to find a support group that fit your needs. Or call
us, your American Cancer Society, at 1-800-227-2345.
What to look for in a stop-smoking program
Stop-smoking programs are designed to help smokers recognize and cope with problems
that come up during quitting. This helps the ex-smoker avoid common pitfalls of quitting.
The programs should also provide support and encouragement in staying quit. Studies
have shown that the best programs include either one-on-one or group counseling.
There’s a strong link between how often and how long counseling lasts (its intensity) and
the success rate — overall, the more intense the program, the greater the chance of
success.
Intensity may be increased by having more or longer sessions or by increasing the
number of weeks over which the sessions are given. So when looking for a program, try
to find one that has the following:
• Each session lasts at least 15 to 30 minutes
• There are at least 4 sessions
• The program lasts at least 2 weeks (longer is usually better)
Make sure the leader of the group is trained in smoking cessation.
Some communities have a Nicotine Anonymous (NicA) group that holds regular
meetings. This group applies the 12-step program of Alcoholics Anonymous (AA) to the
addiction of smoking. This includes attending meetings and following the program.
People new to NicA select a sponsor to help them through the steps and help when they
are tempted to smoke. The NicA meetings are free, but donations are collected to help
cover expenses. NicA also offers online support, Web, and phone meetings.
Often your American Cancer Society, American Lung Association, or local health
department will sponsor quit smoking classes, too. Call us for more information.
Not all programs are honest, so be careful. Think twice about any programs that:
• Promise instant, easy success with little to no effort on your part
• Use shots (injections) or pills, especially “secret” ingredients

• Advertise 100% success rate with no ill effects
• Charge a very high fee (check with the Better Business Bureau if you have doubts)
• Will not give you references and phone numbers of people who have used the
program
Support of family and friends
Many former smokers say a support network of family and friends was very important
during their quit attempt. Other people who may offer support and encouragement are
your co-workers and your family doctor. Tell your friends about your plans to quit. Try to
spend time with non-smokers and ex-smokers who support your efforts to quit. Talk with
them about what you need — for instance, patience as you go through cravings, taking
your late-night or early-morning phone calls, and plans for doing things in smoke-free
settings. Find out what you can count on each friend or family member to do.
Help with the physical part of addiction
Remember, tobacco addiction is both mental and physical. For most people, the best way
to quit will be some combination of medicine, a method to change personal habits, and
emotional support.
Nicotine replacement therapy
As mentioned earlier, the nicotine in cigarettes leads to actual physical dependence. This
can cause unpleasant symptoms when a person tries to quit. Nicotine replacement therapy
(NRT) gives you nicotine – in the form of gums, patches, sprays, inhalers, or lozenges –
but not the other harmful chemicals in tobacco. NRT can help relieve some of the
physical withdrawal symptoms so that you can focus on the psychological (emotional)
aspects of quitting.
How nicotine replacement works
Nicotine replacement therapy (NRT) can help with the difficult withdrawal symptoms
and cravings that 70% to 90% of smokers say is their only reason for not giving up
cigarettes. Using NRT reduces those symptoms.
Many smokers can quit smoking without using NRT, but most of those who attempt
quitting do not succeed on the first try. In fact, smokers usually need many tries –
sometimes as many as 8 to 10 – before they are able to quit for good.
Lack of success is often related to the onset of withdrawal symptoms. And most quitters
go back to smoking within the first 3 months of quitting. So don’t be discouraged if you
start smoking again. Just make a plan to stop again, and make your attempt more
successful by adding another method or technique to help you quit. You can reduce

withdrawal symptoms with NRT and reduce the way they affect you by getting support.
This gives you a better chance of quitting and staying quit.
Getting the most from nicotine replacement
Nicotine replacement therapy (NRT) only deals with the physical dependence. It’s not
meant to be the only thing you use to help you quit smoking. You’ll need other methods
that help with the psychological (emotional and mental) part of smoking, such as a stop
smoking program. Use these support systems during treatment with NRT and for at least
a few months after you quit. Studies have shown that this approach – pairing NRT with a
program that helps to change behavior – can improve your chances of quitting and
staying that way compared to approaches that use only one method.
The best time to start NRT is when you first quit. Many smokers ask if it’s OK to start
NRT while they’re still smoking. At this time the companies that make NRT products say
that they should not be used if you are still smoking, and the FDA has not approved them
to be used in this way in the United States. But some research has been done with
smokers using NRT while still smoking, with the intent to cut down on cigarettes and,
over time, stop completely.
In 2009, researchers looked at several studies in which active smokers were given NRT
over the long term. Overall, those who got NRT were more likely to quit smoking than
those who got placebo (fake NRT), but all the studies included a lot of support and
supervision from the doctor and health team. Side effects were minor in these studies.
The most important thing is being sure that you are not overdosing on nicotine, which can
affect your heart and blood circulation. It’s safest to be under a doctor’s care if you wish
to try smoking and using NRT while you are tapering down your cigarette use.
Often smokers first try to quit on their own then decide to try NRT a day or more into
quitting. This method does not give you the greatest chance of success, but don’t let this
discourage you. There are many options available for quitting smoking and staying quit.
Just remember that it often takes many tries.
Are there smokers who should not use NRT?
The US Agency for Healthcare Research and Quality (AHRQ) Clinical Practice
Guideline on Smoking Cessation in 2000 stated that NRT was safe for all adult smokers
except pregnant women and people with heart or circulatory diseases. But the 2008
Clinical Practice Guidelines for treating tobacco dependence says that NRT (in this case,
the nicotine patch) can be used safely under a doctor’s careful monitoring, even in people
who have heart or blood vessel disease. Studies have found the benefits of quitting
smoking outweigh the risks of NRT in people with cardiovascular (heart and blood
vessel) disease. When looking at NRT use, the benefits of quitting smoking must
outweigh the potential health risks of NRT for each person.
As of late 2012 there’s still not enough good evidence one way or the other to be sure that
NRT is safe for pregnant women. A 2012 analysis of 6 studies done on NRT in 1,745
pregnant women showed no significant differences in ill effects (such as miscarriage,

premature birth, low birth-weight and newborn admission to an intensive care unit)
between the NRT groups and the groups that didn’t get NRT.
Smoking during pregnancy can cause these problems and many others, so many doctors
think NRT is less harmful than smoking during pregnancy. Also, while NRT exposes the
fetus to nicotine, smoking exposes the fetus to nicotine and a number of other chemicals,
too. Nicotine may have unknown effects as the child grows up, and this has not been
carefully studied over the long term. With all of this in mind, it’s best to quit smoking
before getting pregnant. If it’s too late for that, quitting in early pregnancy can still
greatly reduce many risks to the baby. Smokers who find themselves pregnant should talk
with their doctors right away to get help in choosing the best way for them to quit
smoking.
Note that NRT has not yet been proven to help people who smoke fewer than 10
cigarettes a day. You might want to talk with your doctor about a lower dose of NRT if
you smoke less than that but feel you need nicotine replacement.
When may I begin using nicotine replacement therapy?
You can start using NRT as soon as you throw away that last cigarette. You don’t need to
wait a certain length of time to put on the patch or start using the gum, lozenge, nasal
spray, or inhaler. You should double-check this information with the instructions on your
chosen method of nicotine replacement, but in general there is no need to wait to start
using NRT.
Can you get too much nicotine from NRT?
Nicotine overdose is rare, but possible. NRT products are labeled to match the amount of
nicotine you get from NRT to the amount you got when you smoked. If used this way,
you are getting a nicotine dose fairly close to what you’ve been getting from cigarettes.
You don’t want to get more than that, because higher doses of nicotine can cause harm.
Even just a bit too much can cause some of the milder symptoms below. To avoid this,
follow dosing instructions carefully. Also, don’t use heat (like a heating pad or heat lamp)
on the skin at your nicotine patch—the extra blood supply could cause you to absorb
more nicotine. An overdose can cause death. Because of their smaller size, overdose is
more of a problem in children and pets.
Nicotine absorbs through the skin, so you must store and dispose of your NRT safely.
Keep NRT and any used gum or patches and empty cartridges, bottles, etc., safely away
from children and pets.
It’s very rare for an adult who is following the instructions to get a serious overdose. But
with liquid forms (such as sprays and inhalers) that can absorb quickly through the skin,
overdose could happen. All forms of nicotine can cause harm if too much is taken in.
Here are some symptoms of too much nicotine:
• Headache

• Nausea and vomiting
• Belly pain
• Diarrhea
• Fast or irregular heartbeat
• Cold sweat
• Pale skin and mouth
• Weakness
• Tremors (shaking)
• Confusion
• Disturbed vision and hearing
• Weakness
• Dizziness or faintness due to low blood pressure
• Seizures
• Stopped breathing
Call Poison Control and get emergency help if you suspect an overdose. If you are taking
NRT as prescribed and are still having mild symptoms such as headache, vomiting,
diarrhea, or sweating, lower your dose and talk to your doctor.
How do I know if I’m a light, average, or heavy smoker?
Most NRT products are recommended on the basis of how much you smoke. But there’s
no formal category in any textbook or a group that defines a light, average, or heavy
smoker.
In general, a light smoker is someone who smokes fewer than 10 cigarettes per day.
Someone who smokes a pack a day or more is thought of as a heavy smoker. An average
smoker falls in between.
Sometimes a doctor will use the term pack year to describe how long and how much a
person has smoked. A pack year is defined as the number of packs of cigarettes a person
has smoked every day multiplied by the number of years he or she has smoked. Since 1
pack is 20 cigarettes, a person who has smoked 20 cigarettes a day for 1 year is
considered to have smoked 1 pack year. Someone who has smoked 30 cigarettes a day
(1½ packs) for 4 years is described as having smoked 6 pack years (1½ x 4), and so on.
This is another way to figure out how high your risk of smoking-related disease might be.

What are the types of nicotine replacement therapy?
The US Food and Drug Administration (FDA) has approved 5 types of nicotine
replacement therapy:
• Patch
• Gum
• Nasal spray
• Inhalers
• Lozenges
Nicotine patches (transdermal nicotine systems): Patches give a measured dose of
nicotine through the skin. You are weaned off nicotine by switching to lower-dose
patches over a course of weeks. Patches can be bought with or without a prescription.
Many types and different strengths are available. Package instructions tell you how to use
the product, and list special considerations and possible side effects. Follow the directions
carefully.
The 16-hour patch works well if you are a light-to-average smoker. It’s less likely to
cause side effects like skin irritation, racing heartbeat, sleep problems, and headache. But
it does not deliver nicotine during the night, so it may not be right for those with early
morning withdrawal symptoms.
The 24-hour patch provides a steady dose of nicotine, avoiding peaks and valleys. It helps
with early morning withdrawal. But there may be more side effects like disrupted sleep
patterns and skin irritation.
Depending on body size and smoking habits, most smokers should start using a full-
strength patch (15-22 mg of nicotine) daily for 4 weeks, and then use a weaker patch (5-
14 mg of nicotine) for another 4 weeks. The patch should be put on in the morning on a
clean, dry area of the skin without much hair. It should be placed below the neck and
above the waist — for example, on the upper arm or chest. The FDA has approved using
the patch for a total of 3 to 5 months.
Side effects are related to:
• The dose of nicotine
• The brand of patch
• Skin characteristics and allergies (some people have reactions to the patch)
• How long the patch is used
• How it is applied
Some possible side effects of the nicotine patch include:

• Skin irritation (redness and itching)
• Dizziness
• Racing heartbeat
• Sleep problems or unusual dreams
• Headache
• Nausea
• Muscle aches and stiffness
No one has all of the side effects, and some people have none. Some side effects, such as
racing heart, may occur because the dose of nicotine is too high for you. Stop using the
patch and talk to your doctor if this happens. You can also have nicotine withdrawal
symptoms during this time if your NRT dose is too low.
What to do about side effects
• Do not smoke while you are using a patch unless your doctor tells you it’s OK.
• Try a different brand of patch if your skin becomes irritated.
• Reduce the amount of nicotine by using a lower-dose patch.
• Sleep problems may go away in 3 or 4 days. If not, and you’re using a 24-hour patch,
try switching to a 16-hour patch.
• Stop using the patch and try a different form of NRT.
Nicotine gum (nicotine polacrilex): Nicotine gum is a fast-acting form of replacement
in which nicotine is taken in through the mucous membrane of the mouth. You can buy it
over the counter without a prescription. It comes in 2 mg and 4 mg strengths.
For best results, follow the instructions in the package. Chew the gum slowly until you
get a peppery taste or tingle. Then hold it inside your cheek until the taste fades. Chew it
to get the peppery taste back, and park it again. Do this off and on for 20 to 30 minutes.
Food and drink can affect how well the nicotine is absorbed, so don’t eat or drink for at
least 15 minutes before and during gum use.
In choosing your dose, think about whether you
• Smoke 25 or more cigarettes per day
• Smoke within 30 minutes of waking up
• Have trouble not smoking in restricted areas
If any of these describe you, you may need to start with the higher gum dose (4 mg).

Chew no more than 24 pieces of gum in one day. Nicotine gum is usually recommended
for 6 to 12 weeks, with the maximum being 6 months. Tapering down the amount of gum
you use as you approach 3 months may help you stop using it.
If you have sensitive skin, you might prefer the gum to the patch.
Another advantage of nicotine gum is that it allows you to control the nicotine doses. The
gum can be used as needed or on a fixed schedule during the day. The most recent
research has shown that scheduled dosing works better. A schedule of 1 to 2 pieces per
hour is common. On the other hand, with an as-needed schedule, you can use it when you
need it most — when you have cravings.
Some possible side effects of nicotine gum:
• Bad taste
• Throat irritation
• Mouth sores
• Hiccups
• Nausea
• Jaw discomfort
• Racing heartbeat
• Nausea
The gum can also stick to and damage dentures and dental work.
Symptoms related to the stomach and jaw are usually caused by improper use of the gum,
such as swallowing the nicotine or chewing too fast. No one has all of the side effects,
and some people have none. If your heart is racing or beating irregularly, stop using the
gum and talk to your doctor. You can also have nicotine withdrawal symptoms during
this time if your NRT dose is too low.
Long-term dependence is one possible drawback of nicotine gum. In fact, research has
shown that 15% to 20% of gum users who are able to quit smoking keep using the gum
for a year or longer. Nicotine is addictive, and people can transfer their dependence from
cigarettes to the gum. The maximum recommended length of use is 6 months, but
continuing to use the gum may be safer than going back to smoking. Because there’s little
research on the health effects of long-term nicotine gum use, most health care providers
still recommend limiting its use to 6 months. Talk to your doctor if you are having
trouble stopping the gum.
Nicotine nasal spray: The nasal spray delivers nicotine to the bloodstream quickly
because it’s absorbed through the nose. Nicotine nasal spray requires a doctor’s
prescription.

The nasal spray relieves withdrawal symptoms very quickly and lets you control your
nicotine cravings. Smokers usually like the nasal spray because it’s easy to use. Nicotine
is addictive, and a person can transfer their dependence from cigarettes to the fast-
delivering nasal spray. Use it only as long as you need it, as prescribed by your doctor.
The FDA recommends that the spray be prescribed for 3-month periods and that it not be
used for longer than 6 months.
The most common side effects last about 1 to 2 weeks and can include:
• Nasal irritation
• Runny nose
• Watery eyes
• Sneezing
• Coughing
There’s also the danger of using more than is needed. If you have asthma, allergies, nasal
polyps, or sinus problems, your doctor may suggest another form of NRT.
This form of NRT poses a more serious risk to small children and pets, since even empty
bottles of nasal spray contain enough nicotine to harm them. Nicotine absorbs through the
skin as well as mucous membranes like the mouth or eyes, and can cause serious harm. If
there’s any skin contact, rinse thoroughly with plain water right away. If a bottle breaks
or liquid leaks out, put on plastic or rubber gloves to clean it up. Call Poison Control and
get emergency help if there’s any question of overdose.
Nicotine inhalers: Inhalers are available only by prescription. The nicotine inhaler is a
thin plastic tube with a nicotine cartridge inside. It looks a bit like a fat cigarette with a
mouthpiece. When you take a puff from the inhaler, the cartridge puts out a nicotine
vapor. Unlike other inhalers, which deliver most of the medicine to the lungs, the nicotine
inhaler delivers most of the nicotine vapor to the mouth where it’s absorbed into the
bloodstream. Nicotine inhalers are the FDA-approved nicotine replacement method that’s
most like smoking a cigarette, which some smokers find helpful.
The recommended dose is between 4 and 20 cartridges a day, for up to 6 months.
The most common side effects, especially when first using the inhaler, include:
• Coughing
• Upset stomach
This form of NRT poses an extra risk to small children and pets because the used
cartridges still have enough nicotine in them to cause harm if it gets on skin or mucous

membranes (for instance, if licked or touched to the eyes, mouth, or other mucous
membrane). Be sure to store and dispose of the cartridges away from children and pets.
At this time, inhalers are the most expensive forms of NRT available. They are not the
same as electronic cigarettes, which have not been proven in clinical trials to help with
quitting and are not approved by the FDA. (For more on these, see “Other nicotine and
tobacco products not reviewed or approved by the FDA” in the “Other methods of
quitting” section.)
Nicotine lozenges: Nicotine-containing lozenges can be bought without a prescription.
Like nicotine gum, the lozenge is available in 2 strengths: 2 mg and 4 mg. Smokers
choose their dose based on how long after waking up they normally have their first
cigarette.
Lozenge makers recommend using them as part of a 12-week program. The
recommended dose is 1 lozenge every 1 to 2 hours for 6 weeks, then 1 lozenge every 2 to
4 hours for weeks 7 to 9, and finally, 1 lozenge every 4 to 8 hours for weeks 10 to 12.
The lozenge makers also recommend:
• Stop all smoking when you start using the lozenge.
• Do not eat or drink for 15 minutes before using a lozenge. (Some drinks can reduce
how well the lozenge works.)
• Suck on the lozenge until it is fully dissolved, about 20 to 30 minutes. Do not bite or
chew it like a hard candy, and don’t swallow it. The nicotine absorbs through the
mucous membranes of the mouth.
• Do not use more than 5 lozenges in 6 hours, or more than 20 lozenges per day.
• Stop using the lozenge after 12 weeks. If you still feel you need to use the lozenge,
talk to your doctor.
• Do not use the lozenge if you keep smoking, chewing tobacco, using snuff, or use any
other product containing nicotine (such as the nicotine patch or nicotine gum).
Possible side effects of the nicotine lozenge include:
• Trouble sleeping
• Nausea
• Hiccups
• Coughing
• Heartburn
• Headache
• Flatulence (gas)

Which type of nicotine replacement may be right for you?
There’s no evidence that any one type of nicotine replacement therapy (NRT) is any
better than another. When choosing which type of NRT you will use, think about which
method will best fit your lifestyle and pattern of smoking. Do you want/need something
in your mouth or something to keep your hands busy? Or are you looking for once-a-day
convenience?
Some important points to think about:
• Nicotine gums, lozenges, and inhalers are substitutes you can put into your mouth
that let you control your dosage to help keep cravings under better control.
• Nicotine gums and lozenges are generally sugar-free, but if you are diabetic and have
any doubts, check with the manufacturer.
• Nicotine nasal spray works very quickly when you need it.
• Nicotine inhalers allow you to mimic the use of cigarettes by puffing and holding the
inhaler. It also works very quickly.
• Nicotine patches are convenient and only have to be put on once a day.
• Both inhalers and nasal sprays require a doctor’s prescription.
• Some people may not be able to use patches, inhalers, or nasal sprays because of
allergies or other conditions.
• Nicotine gum may stick to dentures or dental work making it hard to chew before
“parking.”
Whatever type you use, take your NRT at the recommended dose, and use it only for as
long as it’s recommended. If you use a different dose or stop taking it too soon, it can’t be
expected to work like it should. If you are a very heavy smoker or a very light smoker,
you may want to talk with your doctor about whether your NRT dose should be changed
to better suit your needs.
Combining the patch and other nicotine replacement products: Using the nicotine
patch along with shorter-acting products, like the gum, lozenge, nasal spray, or inhaler, is
another method of NRT. The idea is to get a steady dose of nicotine with the patch and
then use one of the shorter-acting products when you have strong cravings.
The few studies that have been done on combination NRT used this way have found that
it may work better than a single product. Still, more research is needed to prove this and
find safe and effective doses. And the combined use of NRT products has not yet been
approved by the FDA. If you’re thinking about using more than one NRT product, be
sure to talk it over with your doctor first.
High-dose nicotine replacement therapy for heavy smokers: Another NRT option is
to give smokers a higher dose based on the amount of nicotine that they have been getting

from cigarettes. Sometimes this method has required larger than usual doses of NRT.
High-dose NRT with patches has been studied with patients getting from 35 mg to 63 mg
of nicotine per day. The research suggests that patients’ withdrawal symptoms go away
with these higher doses and their cravings improve without harmful effects on the heart
and circulation. Patients were carefully watched in these studies to make sure they were
OK and were not becoming ill or having any problems. But not much is known about this
option and it should be considered only with a doctor’s guidance and supervision. It may
worsen things if you already have heart disease or other health problems.
Stopping nicotine replacement therapy
As mentioned before, most forms of NRT are meant to be used for limited periods of
time. Use should be tapered down to a low dose before NRT is stopped.
Research is still being done to refine the use of NRT. For example, even though the patch
is usually used for 3 to 5 months, some studies have suggested that using it for 8 weeks or
less works just as well. But other researchers have noted that the risk of relapse goes up
when nicotine replacement is stopped, even after it has been used for 5 months. These
differences have not been fully explained. More studies are needed to learn which
smokers are likely to be successful using shorter or longer NRT than usual. If you feel
that you need NRT for a different length of time than is recommended, it’s best to discuss
this with your doctor.
Prescription drugs
Prescription drugs are also available to help smokers quit. Some can be used along with
nicotine replacement therapy (NRT), and some must be started before your planned Quit
Day. Talk to your doctor if you want to use medicine to help you quit smoking. You will
need a prescription for any of these drugs.
Bupropion (Zyban)
Bupropion (Zyban®
, Wellbutrin®
, or Aplenzin®
) is a prescription anti-depressant in an
extended-release form that reduces symptoms of nicotine withdrawal. It does not contain
nicotine. This drug acts on chemicals in the brain that are related to nicotine craving.
Bupropion works best if it’s started 1 or 2 weeks before you quit smoking. The usual
dosage is one or two 150 mg tablets per day.
If you are able to quit smoking after 7 to 12 weeks of bupropion your doctor may have
you keep taking it for some time afterward to help keep you from going back to smoking.
Keep up with your other support systems during this time and for a few months after you
quit.
This drug should not be taken if you have ever had seizures (it can cause or worsen
seizures), heavy alcohol use, serious head injury, bipolar (manic-depressive) illness, or
anorexia or bulimia (eating disorders).

Reported side effects of bupropion include dry mouth, trouble sleeping, appetite changes,
agitation, constipation, and headaches. People using bupropion should call their doctors if
they feel depressed or start thinking of suicide. They should also call their doctors for
changes such as feeling anxious, agitated, hostile, aggressive, overly excited and
hyperactive, or not being able to sleep. These are rare, but can happen, often near the start
of treatment or after a dose change.
Some doctors may recommend combination therapy for heavily addicted smokers, such
as using bupropion along with a nicotine patch and/or a short-acting form of NRT (such
as gum or lozenges). The combination has been found to work better for some people
than using any one part alone.
Varenicline (Chantix)
Varenicline (Chantix®
) is a prescription medicine developed to help people stop smoking.
It works by interfering with nicotine receptors in the brain. This means it has 2 effects: it
lessens the pleasure a person gets from smoking, and it reduces the symptoms of nicotine
withdrawal. Varenicline should be started a week before your Quit Day.
Several studies have shown taking varenicline can more than double the chances of
quitting smoking when compared to taking no medicines at all. Some studies have also
found it may work better than bupropion, at least in the short term.
Varenicline comes in pill form and is taken after meals, with a full glass of water. The
daily dose increases over the first 8 days it is taken. The dose starts at one 0.5 mg pill a
day for the first 3 days, then the 0.5 mg pill twice a day for the next 4 days. At the start of
the second week, the dose is raised to 1 mg in the morning and evening. For people who
have problems with the higher dose, a lower dose may be used during the quit effort.
Varenicline is given for 12 weeks, but people who quit during that time may get another
12 weeks of treatment to boost their chances of not smoking. Keep up with your other
support systems during this time and for a few months after you quit.
Reported side effects of varenicline have included headaches, nausea, vomiting, trouble
sleeping, unusual dreams, flatulence (gas), and changes in taste. People with heart disease
may have a higher risk of heart attacks while on varenicline. There have also been reports
of depressed mood, thoughts of suicide, attempted suicide, and changes in behavior in
people taking varenicline. People who have these problems should contact their doctors
right away. Reports of these side effects have been rare, but they can be serious when
they do happen. Most people who take varenicline tolerate it well.
Not much research has been done to find out if varenicline is safe to use at the same time
as nicotine replacement therapy (NRT) products. One study has suggested that using
varenicline along with NRT is well-tolerated and safe, even though more people taking
both drugs had side effects than those taking only one. The company that makes
varenicline had already noted that people who used the drug along with NRT had more
side effects such as nausea and headaches. More research is needed.

“Off-label” drugs to help smokers quit
For those who cannot use any of the FDA-approved drugs for helping smokers quit, or
for those who have not been able to quit using them, other drugs have shown promise in
research studies. They are recommended by the Agency for Healthcare Research and
Quality for this kind of use, but have not been approved by the FDA for this purpose and
so are used “off-label.” (See our document called Off Label Drug Use for more on this.)
These drugs are only available with a prescription and are not recommended for pregnant
smokers, teens, or people who smoke less than 10 cigarettes per day.
Nortriptyline
This is an older anti-depressant drug. When used in groups of smokers, it has been found
to double the chances of success in quitting smoking when compared to those taking no
medicine. It’s started 10 to 28 days before you stop smoking to allow it to reach a stable
level in the body.
Some people have side effects like a fast heart rate, blurred vision, trouble urinating, dry
mouth, constipation, weight gain or loss, and low blood pressure when they stand up. The
drug can affect your ability to drive or operate machinery, and certain drugs cannot be
used along with it.
Be sure your doctor and pharmacist know exactly what else you are taking before you
start this medicine. Also be sure you know how to take it and how to taper it down when
you are ready to stop. The dose of nortriptyline must be slowly lowered, since the drug
cannot be stopped suddenly without the risk of serious effects. The drug must be used
cautiously in people with heart disease. While you are taking it, be sure to tell any doctor
you visit that you are taking the drug.
Clonidine
Clonidine is another older drug. It’s FDA approved to treat high blood pressure. When
used for smoking cessation, it can be given as a pill twice a day or as a once-a-week skin
patch. In one study of heavy smokers who had failed in previous quit attempts, the group
treated with clonidine was twice as likely to succeed in quitting smoking as the control
group (which was given a fake pill) at the end of 4 weeks.
Be sure your doctor and pharmacist know exactly what else you are taking before you
start this medicine. The most common side effects of clonidine are constipation,
dizziness, drowsiness, dry mouth, and unusual tiredness or weakness. There are rarely
more severe side effects, such as allergic reactions, a slow heart rate, and very high or
very low blood pressure. Your doctor may want to watch your blood pressure while you
are on this drug. The drug can affect your ability to drive or operate machinery
Clonidine can be started up to 3 days before you quit smoking, but can also be started the
day you quit. Like nortriptyline, it shouldn’t be stopped suddenly. The dose must be
lowered over 2 to 4 days to prevent a rapid increase in blood pressure, agitation,
confusion, or tremors.

Other drugs being studied to help smokers quit
Other medicines such as naltrexone, which comes as a pill, are being studied. It’s being
used along with other treatments (like bupropion and NRT) to see if it can help reduce
cravings.
Another drug called cytisine was recently tested in Poland and found to help reduce
smoking when compared to placebo. About 8% of smokers still didn’t smoke after a year,
compared to about 2% of those on placebo.
Also still being tested are anti-smoking vaccines that are given as a series of shots.
Tests of these new treatments have been promising. So far they seem to be safe, but
larger studies are needed to show these treatments work before the FDA can approve
them for this use. Large studies of these treatments are now under way.
Other methods of quitting
Other tools may help some people, but there’s no strong proof that they can improve your
chances of quitting.
Methods without nicotine
Hypnosis
Hypnosis methods vary a great deal, which makes it hard to study as a way to stop
smoking. For the most part, reviews that looked at controlled studies of hypnosis to help
people quit smoking have not supported it as a quitting method that works. Still, some
people find it useful. If you would like to try it, ask your doctor if he or she can
recommend a good hypnotherapist.
Acupuncture
This method has been used to quit smoking, but there’s little evidence to show that it
works. Acupuncture for smoking is usually done on certain parts of the ears. (See our
document, Acupuncture for more on this.) For a list of doctors who do acupuncture,
contact the American Academy of Medical Acupuncture at 323-937-5514 or visit their
Web site at www.medicalacupuncture.org.
Low-level laser therapy
This technique, also called cold laser therapy, is related to acupuncture. Cold lasers are
sometimes used instead of needles for acupuncture. The treatment is supposed to relax
the smoker and release endorphins (pain relief substances that are made naturally by the
body) to mimic the effects of nicotine in the brain, or balance the body’s energy to relieve
the addiction. Despite claims of success by some cold laser therapy providers, there’s no

scientific evidence that shows this helps people stop smoking. (See our document called
Cold Laser Therapy for more.)
Filters
Filters that reduce tar and nicotine in cigarettes do not work. In fact, studies have shown
that smokers who use filters tend to smoke more.
Smoking deterrents
Other methods have been used to help stop smoking, such as over-the-counter products
that change the taste of tobacco, stop-smoking diets that curb nicotine cravings, and
combinations of vitamins. At this time there’s little scientific evidence that any of these
work.
Herbs and supplements
There’s little scientific evidence to support the use of homeopathic aids and herbal
supplements as stop-smoking methods. Because they are marketed as dietary
supplements (not drugs), they don’t need FDA approval to be sold. This means that the
manufacturers don’t have to prove they work, or even that they’re safe.
Be sure to look closely at the label of any product that claims it can help you stop
smoking. No dietary supplement has been proven to help people quit smoking. Most of
these supplements are combinations of herbs, but not nicotine. They have no proven track
record of helping people to stop smoking.
Other nicotine and tobacco products not reviewed or
approved by the FDA
Tobacco lozenges and pouches
Lozenges that contain tobacco and small pouches of tobacco that you hold in your mouth
are being sold as other ways for smokers to get nicotine in places where smoking is not
allowed. The FDA has ruled that these are types of oral tobacco products much like snuff
and chew, and are not smoking cessation aids. There’s no evidence that these products
can help a person quit smoking. Unlike scientifically proven treatments with known
effects, such as nicotine replacement products, anti-depressants, nicotine receptor
blockers, or behavioral therapy, these tobacco products have never been tested to see if
they can help people quit tobacco.
We know that oral tobacco products such as snuff and chewing tobacco contain human
carcinogens. These products cause mouth cancer and gum disease. They also destroy the
bone sockets around teeth and can cause teeth to fall out. There are studies showing
potential harmful effects on the heart and circulation, as well as increased risks of other

cancers. They also cause bad breath and stain the teeth. They are not safe alternatives to
cigarettes, nor do they help people quit tobacco.
Electronic cigarettes
In 2004, a Chinese company started making a refillable “cigarette” with a battery and an
electronic chip in it. It’s designed to look like a cigarette, right down to the glowing tip.
When the smoker puffs on it, the system delivers a mist of liquid, flavorings, and nicotine
that looks something like smoke. The smoker inhales it like cigarette smoke, and the
nicotine is absorbed into the lungs.
The electronic cigarette, or e-cigarette, is sold with cartridges of nicotine and flavorings.
Several brands and varieties of the e-cigarette are now sold in the United States. The e-
cigarette is usually sold as a way for a smoker to get nicotine in places where smoking is
not allowed, but some have sold it as a way to quit smoking. The cartridges are sold as
having different doses of nicotine, from high doses to no nicotine at all.
The e-cigarette has no published clinical trials that suggest it might work as a way to help
smokers quit. No clinical trials have been submitted to the FDA. As of late 2011, the
courts determined that the FDA could regulate e-cigarettes like they do other tobacco
products, under the Tobacco Control Act. But if e-cigarettes are marketed for therapeutic
purposes (such as quitting smoking), they would be regulated as drugs and/or devices.
There are questions about how safe it is to inhale some substances in the e-cigarette vapor
into the lungs. The ingredients in e-cigarettes are not labeled, so the user doesn’t know
what’s in them. The amounts of nicotine and other substances a person gets from each
cartridge are also unclear. The manufacturers say that the ingredients are safe, but it’s not
clear if they are safe to inhale — many substances that are safe to eat can harm delicate
tissues inside the lungs.
Information from the FDA suggests that e-cigarettes are not always safe. A 2009 analysis
of 18 samples of cartridges from 2 leading e-cigarette brands found cancer-causing
substances in half the samples. There were other impurities noted as well. For example,
diethylene glycol, a toxic ingredient found in antifreeze, was found in one sample.
Information from the same testing suggests that there may be manufacturing problems
with some brands of e-cigarettes. Nicotine levels from each puff varied a great deal, even
between cartridges labeled as having the same nicotine amounts. Testing also found small
amounts of nicotine in most of the cartridges labeled nicotine-free.
Like other forms of nicotine, the e-cigarettes and nicotine cartridges can be toxic to
children or pets. They can also pose a choking hazard.
Electronic cigarettes are now being used differently from when they were first
introduced. Some sellers offer liquids that can be added to e-cigarette systems as a way to
take in drugs other than nicotine. For instance, they advertised Cialis®
(tadalafil) could be
put into inhalation cartridges and “smoked.” Some companies have offered vitamins and
an unapproved drug that is supposed to curb cravings and appetite. The FDA has warned

at least one US company about this, but new sellers are cropping up in countries with less
stringent drug laws.
Nicotine lollipops and lip balms
In the past, some pharmacies made a product called a nicotine lollipop. These lollipops
often contained a product called nicotine salicylate, which is not approved by the FDA
for pharmacy use. The FDA warned pharmacies to stop selling nicotine lollipops and lip
balm on the Internet, calling the products “illegal.” The FDA also said “the candy-like
products present a risk of accidental use by children.”
Other smoking cessation products like these that do not use nicotine salicylate may be
legal if they are prescribed by a doctor. Because doses vary, you will need to talk with
your doctor about how to use them. But they still pose a risk for children and pets if they
are not well-labeled, carefully stored, and disposed of safely.
A word about quitting success rates
Before you start using nicotine replacement or sign up for a stop smoking program, you
may wonder about success rates. Success rates are hard to figure out for many reasons.
First, not all programs define success in the same way. Does success mean that a person
is not smoking at the end of the program? After 3 months? 6 months? 1 year? Does
smoking fewer cigarettes (rather than stopping completely) count as success? If a
program you’re considering claims a certain success rate, ask for more details on how
success is defined and what kind of follow-up is done to confirm the rate.
The truth is that quit smoking programs, like other programs that treat addictions, often
have fairly low success rates. But that doesn’t mean they are not worthwhile or that you
should be discouraged. Your own success in quitting and staying that way is what really
counts, and you have some control over that. Even if you don’t succeed the first few
times, keep trying. You can learn from your mistakes so that you will be ready for those
pitfalls the next time.
Success rates in general
Only about 4% to 7% of people are able to quit smoking on any given attempt without
medicines or other help.
Studies in medical journals have reported that about 25% of smokers who use medicines
can stay smoke-free for over 6 months. Counseling and other types of emotional support
can boost success rates higher than medicines alone. There’s also early evidence that
combining some medicines may work better than using a single drug. (See the section,
“Help with the physical part of addiction: Prescription drugs.”)
Behavioral and supportive therapies may increase success rates even further. They also
help the person stay smoke-free. Check the package insert of any product you are using to
see if the manufacturer provides free telephone-based counseling.

How to quit
Smokers often say, “Don’t tell me why to quit, tell me how.” There’s no one right way to
quit, but there are some requirements for quitting with success. These 4 factors are key:
• Making the decision to quit
• Picking a Quit Day and making a plan
• Dealing with withdrawal
• Staying tobacco-free (maintenance)
Making the decision to quit
The decision to quit smoking is one that only you can make. Others may want you to
quit, but the real commitment must come from you.
Think about why you want to quit.
• Are you worried that you could get a smoking-related disease?
• Do you really believe that the benefits of quitting outweigh the benefits of continuing
to smoke?
• Do you know someone who has had health problems because of their smoking?
• Are you ready to make a serious try at quitting?
If you are thinking about quitting, setting a date and deciding on a plan will help move
you to the next step.
Setting a quit date and making a plan
What’s important about picking a Quit Day?
Once you’ve decided to quit, you’re ready to pick a quit date. This is a very important
step. Pick a day within the next month as your Quit Day. Picking a date too far away can
allow you time to rationalize and change your mind. But you want to give yourself
enough time to prepare and come up with a plan. You might choose a date with a special
meaning like a birthday or anniversary, or the date of the Great American Smokeout (the
third Thursday in November each year). Or you might want to just pick a random date.
Circle the date on your calendar. Make a strong, personal commitment to quit on that day.
Remember that if you are planning to use a prescription drug, you will need to talk with
your doctor about getting it in time for your Quit Day. If you plan to use bupropion
(Zyban) or varenicline (Chantix), you must start taking the drug at least a full week, or
maybe even 2 weeks, before your Quit Day. Talk with your doctor about exactly when to

start, and how to use the medicine. Also find out what side effects to watch for and
report. If you are using a prescription drug, put a note on your calendar to remind you to
start taking it before your Quit Day.
Prepare for your Quit Day
There is no one right way to quit. Most smokers prefer to quit cold turkey — they stop
completely, all at once, with no medicines or nicotine replacement. They smoke until
their Quit Day and then quit. Some may smoke fewer cigarettes for 1 or 2 weeks before
their Quit Day. Another way is to cut down on the number of cigarettes you smoke a little
bit each day. This way, you slowly reduce the amount of nicotine in your body. You
might cut out cigarettes smoked with a cup of coffee, or you might decide to smoke only
at certain times of the day. It makes sense to cut down in order to reduce withdrawal
symptoms, but this can be hard to do.
Quitting smoking is a lot like losing weight: it takes a strong commitment over a long
time. Smokers may wish there was a magic bullet – a pill or something that would make
quitting painless and easy – but there’s no such thing. Nicotine substitutes can help
reduce withdrawal symptoms, but they work best when they are used as part of a stop-
smoking plan that addresses both the physical and psychological components of quitting
smoking.
Here are some steps to help you get ready for your Quit Day:
• Pick the date and mark it on your calendar.
• Tell friends and family about your Quit Day.
• Get rid of all the cigarettes and ashtrays in your home, car, and at work.
• Stock up on oral substitutes — sugarless gum, carrot sticks, hard candy, cinnamon
sticks, coffee stirrers, straws, and/or toothpicks.
• Decide on a plan. Will you use NRT or other medicines? Will you attend a stop-
smoking class? If so, sign up now.
• Practice saying, “No thank you, I don’t smoke.”
• Set up a support system. This could be a group program or a friend or family member
who has successfully quit and is willing to help you. Ask family and friends who still
smoke not to smoke around you, and not to leave cigarettes out where you can see
them.
• If you are using bupropion or varenicline, take your dose each day leading up to your
Quit Day.
• Think about your past attempts to quit. Try to figure out what worked and what
didn’t.

Successful quitting is a matter of planning and commitment, not luck. Decide now on
your own plan. Some options include using nicotine replacement or other medicines,
joining a stop-smoking class, going to Nicotine Anonymous meetings, using self-help
materials such as books and pamphlets, or some combination of these methods. For the
best chance at success, your plan should include 2 or more of these options.
Your Quit Day
On your Quit Day:
• Do not smoke. This means none at all — not even one puff!
• Keep active — try walking, exercising, or doing other activities or hobbies.
• Drink lots of water and juices.
• Begin using nicotine replacement if that’s your choice.
• Attend stop-smoking class or follow your self-help plan.
• Avoid situations where the urge to smoke is strong.
• Avoid people who are smoking.
• Drink less alcohol or avoid it completely.
• Think about how you can change your routine. Use a different route to go to work,
drink tea instead of coffee. Eat breakfast in a different place or eat different foods.
Read on to find out more about the kinds of thoughts and temptations that come up when
you try to quit, and ideas for ways to deal with or avoid them.
Dealing with withdrawal
Withdrawal from nicotine has 2 parts — the physical and the mental. The physical
symptoms are annoying but not life-threatening. Still, if you’re not prepared for them,
they can tempt you to go back to smoking. Nicotine replacement and other medicines can
help reduce many of these symptoms. Most smokers find that the mental part of quitting
is the bigger challenge.
If you have been smoking for any length of time, smoking has become linked with a lot
of the things you do — waking up in the morning, eating, reading, watching TV, and
drinking coffee, for example. It will take time to “un-link” smoking from these activities.
This is why, even if you’re using a nicotine replacement, you may still have strong urges
to smoke.

Rationalizations are sneaky
One way to overcome these urges or cravings is to notice and identify rationalizations as
they come up. A rationalization is a mistaken thought that seems to make sense to you at
the time, but the thought isn’t based on reality. If you choose to believe in such a thought
even for a short time, it can serve as a way to justify smoking. If you have tried to quit
before, you will probably recognize many of these common rationalizations:
• “I’ll just have one to get through this rough spot.”
• “Today is not a good day. I’ll quit tomorrow.”
• “It’s my only vice.”
• “How bad is smoking, really? Uncle Harry smoked all his life and he lived to be over
90.”
• “Air pollution is probably just as bad.”
• “You’ve got to die of something.”
• “Life is no fun without smoking.”
You probably can add more to the list. As you go through the first few days without
smoking, write down any rationalizations as they come up and recognize them for what
they are: messages that can trick you into going back to smoking. Look out for them,
because they always show up when you’re trying to quit. After you write down the
thought, let it go and move on. Be ready with a distraction, a plan of action, and other
ways to re-direct your thoughts to something else.
Use these ideas to help you stay committed to quitting
Avoid temptation. Stay away from people and places that tempt you to smoke. Later on
you’ll be able to handle these with more confidence.
Change your habits. Switch to juices or water instead of alcohol or coffee. Choose foods
that don’t make you want to smoke. Take a different route to work. Take a brisk walk
instead of a coffee break.
Choose other things for your mouth: Use substitutes you can put in your mouth
such as sugarless gum or hard candy, raw vegetables such as carrot sticks, or
sunflower seeds. Some people chew on a coffee stirrer or a straw.
Get active with your hands: Do something to reduce your stress. Exercise or do
something that keeps your hands busy, such as needlework or woodworking,
which can help distract you from the urge to smoke. Take a hot bath, go for a
walk, or read a book.
Breathe deeply: When you were smoking, you breathed deeply as you inhaled
the smoke. When the urge strikes now, breathe deeply and picture your lungs

filling with fresh, clean air. Remind yourself of your reasons for quitting and the
benefits you’ll gain as an ex-smoker.
Delay: If you feel that you are about to light up, hold off. Tell yourself you must
wait at least 10 minutes. Often this simple trick will allow you to move beyond
the strong urge to smoke.
Reward yourself. What you’re doing is not easy, so you deserve a reward. Put the
money you would have spent on tobacco in a jar every day and then buy yourself a
weekly treat. Buy a book or some new music, go out to eat, start a new hobby, or join a
gym. Or save the money for a major purchase.
You can also reward yourself in ways that don’t cost money: visit a park or go to the
library. Check local news listings for museums, community centers, and colleges that
have free classes, exhibits, films, and other things to do.
Staying smoke-free
Remember the Mark Twain quote? Maybe you, too, have quit many times before. If so,
you know that staying quit is the final, longest, and most important stage of the process.
You can use the same methods as you did to help you through withdrawal. Think ahead
to those times when you may be tempted to smoke, and plan on how you will use other
ways to cope with those situations.
More dangerous, perhaps, are the unexpected strong desires to smoke that can sometimes
happen months or even years after you’ve quit. Rationalizations can show up then, too.
To get through these without relapse, try these:
• Remember your reasons for quitting and think of all the benefits to your health, your
finances, and your family.
• Remind yourself that there is no such thing as just one cigarette — or even just one
puff.
• Ride out the desire to smoke. It will go away, but don’t fool yourself into thinking
you can have just one.
• Avoid alcohol. Drinking lowers your chance of success.
• If you’re worried about weight gain, put some energy into planning a healthy diet and
finding ways to exercise and stay active.
Recovering from slips
What if you do smoke? Here’s the difference between a slip and a relapse: a slip is a one-
time mistake that is quickly corrected. A relapse is going back to smoking. You can use
the slip as an excuse to go back to smoking, or you can look at what went wrong and
renew your commitment to staying away from smoking for good.

Even if you do relapse, try not to get too discouraged. Very few people are able to quit
for good on the first try. In fact, it takes most people several tries before they quit for
good. What’s important is figuring out what helped you when you tried to quit and what
worked against you. You can then use this information to make a stronger attempt at
quitting the next time.
Some special concerns
Weight gain
Many smokers do gain weight when they quit. But even when steps aren’t taken to try to
prevent this, the average gain is less than 10 pounds. Women tend to gain slightly more
weight than men. There’s some evidence that smokers will gain weight after they quit
even if they don’t eat more. Some studies suggest that nicotine replacement therapy or
bupropion may help delay weight gain, but they don’t prevent it.
For some people, a concern about weight gain can lead to a decision not to quit. But the
weight gain that follows quitting smoking is usually small. It’s much more dangerous to
keep smoking than it is to gain a small amount of weight.
You are more likely to quit smoking successfully if you deal with the smoking first, and
then later take steps to lose weight. While you are quitting, try to focus on ways to help
you stay healthy, rather than on your weight. Stressing about your weight may make it
harder to quit. Eat plenty of fruits and vegetables and limit fat. Be sure to drink plenty of
water, and get enough sleep and regular physical activity.
Try walking
Walking is a great way to be physically active and increase your chances of not smoking.
Walking can help you by:
• Reducing stress
• Burning calories and toning muscles
• Giving you something to do instead of thinking about smoking
No special equipment or clothing is needed for walking, other than a pair of comfortable
shoes. And most people can do it pretty much anytime. You can use these ideas as
starting points and come up with more of your own:
• Walk around a shopping mall
• Get off the bus one stop before you usually do
• Find a buddy to walk with during lunch time at work
• Take the stairs instead of the elevator

• Walk with a friend, family member, or neighbor after dinner
• Push your baby in a stroller
• Take a dog (yours or a maybe neighbor’s) out for a walk
Set a goal of at least 2½ hours of moderate intensity physical activity spread throughout
each week. But if you don’t already exercise regularly, check with your doctor before you
start. If you’d like to learn more, please see our American Cancer Society Guidelines on
Nutrition and Physical Activity for Cancer Prevention.
Stress management
Smokers often mention stress as one of the reasons for going back to smoking. Stress is
part of life for smokers and non-smokers alike. The difference is that smokers have come
to use nicotine to help cope with stress and unpleasant emotions. When quitting, you have
to learn new ways of handling stress. Nicotine replacement can help for a while, but over
the long term you will need other methods.
As mentioned before, physical activity is a good stress-reducer. It can also help with the
short-term sense of depression or loss that some smokers have when they quit. There are
also stress-management classes and self-help books. Check your community newspaper,
library, or bookstore.
Spiritual practices involve being part of something greater than yourself. For some, that
includes things like religious practices, prayer, or church work. For others, it may involve
meditation, music, being outside in nature, creative work, or volunteering to help others.
Spirituality can give you a sense of purpose and help you remember why you want to stay
smoke-free.
The spiritual practices of admitting that you cannot control your addiction and believing
that a higher power can give you strength have been used with much success to deal with
other addictions. These practices, along with the fellowship of others on a similar path,
are a key part of 12-step recovery programs. These same principles can be applied to
quitting smoking.
Think about how you can deal with stress and not smoke. Look at the resources around
you and plan on how you will handle the stressors that will come your way.
Taking care of yourself
It’s important for your health care provider to know if you use any type of tobacco now
or have in the past, so that you will get the preventive health care you need. It’s well
known that using tobacco puts you at risk for certain health-related illnesses, so part of
your health care should focus on related screening and preventive measures to help you
stay as healthy as possible. For example, you will want to regularly check inside your
mouth for any changes. Have your doctor or dentist look at your mouth, tongue, or throat
if you have any changes or problems. The American Cancer Society recommends that

medical check-ups should include looking in the mouth. This way, tobacco users may be
able to learn about changes such as leukoplakia (white patches on the mouth tissues)
early, and prevent oral cancer or find it at a stage that’s easier to treat.
You should also be aware of any of the following changes:
• Change in cough
• A new cough
• Coughing up blood
• Hoarseness
• Trouble breathing
• Wheezing
• Headaches
• Chest pain
• Loss of appetite
• Weight loss
• General tiredness
• Frequent lung or bronchial infections
Any of these could be signs of lung cancer or a number of other lung conditions and
should be reported to a doctor right away.
Heavy smokers are at higher risk for lung cancer. But lung cancer often doesn’t cause
symptoms until it’s advanced (has spread). The American Cancer Society is reviewing
the results from the National Lung Screening Trial (NLST), a 2011 study that looked at
whether screening could save lives of people at increased risk for lung cancer. In this
study, heavy smokers and formerly heavy smokers between the ages of 55 and 74 years
old were screened using either chest x-rays or low-dose helical CT scans. The group that
got the CT scans had a slightly lower death rate.
If you are or have been a heavy smoker and are between ages 55 and 74, talk with your
doctor about your lung cancer risk, and about the potential benefits and risks of lung
cancer screening. After discussing what is and is not known about the value of early lung
cancer detection, you and your doctor can decide whether to go ahead with testing. If you
do decide in favor of testing, then be sure to have it done at a center that has experience
in all aspects of testing people at high risk. For more detailed information on this, please
see the American Cancer Society Interim Guidance on Lung Cancer Screening.
Remember that tobacco users have a higher risk for other cancers, too. You can learn
about the types of cancer you may be at risk for by reading our document that discusses
the way you use tobacco (see the “To learn more” section). Other risk factors for these

cancers may be more important than your use of tobacco, but you should know about the
extra risks that might apply to you.
If you have any health concerns that may be related to your tobacco use, please see a
health care provider as soon as possible. Taking care of yourself and getting treatment for
problems early on will give you the best chance for successful treatment. The best way,
though, to take care of yourself and decrease your risk for life-threatening health
problems is to quit using tobacco.
To learn more
It’s hard to stop smoking. But you can quit! Since 2002, there have been more former
smokers in the US than there are current smokers — you can become one of this growing
number!
Many organizations offer information, counseling, and other services to help you quit, as
well as information on where to go for help. Other good resources to ask for help can
include your doctor, dentist, local hospital, or employer.
More information from your American Cancer Society
Here is more information you might find helpful. You also can order free copies of our
documents from our toll-free number, 1-800-227-2345, or read most of them on our Web
site, www.cancer.org.
More on how to quit
Increase Your Chances of Quitting Smoking
Quitting Smoking—Help for Cravings and Tough Situations (also in Spanish)
Smoking and using tobacco
Questions About Smoking, Tobacco, and Health (also in Spanish)
Smokeless Tobacco and How to Quit
Cigarette Smoking (also in Spanish)
Cigar Smoking (also in Spanish)
Child and Teen Tobacco Use
Women and Smoking (also in Spanish)
Smoking in the Workplace—A Model Policy
Tobacco and the LGBT Community

Death and harm from smoking
Smoking and Cancer Mortality Summary Table
Tobacco-Related Cancers Fact Sheet
If someone you know is quitting
Helping a Smoker Quit: Do’s and Don’ts
Cancer screening
American Cancer Society Interim Guidance on Lung Cancer Screening
National organizations and Web sites*
If you want to quit smoking and need help, contact one of the following organizations.
Along with the American Cancer Society, other sources of information and support
include:
Nicotine Anonymous (NicA)
Toll-free number: 1-877-879-6422 (1-877-TRY-NICA)
Web site: www.nicotine-anonymous.org
For free information on their 12-step program, meeting schedules and locations,
print materials, or information on how to start a group in your area
QuitNet
Web site: www.quitnet.com
Offers free, cutting edge, services to people trying to quit tobacco
Centers for Disease Control and Prevention
Office on Smoking and Health
Free quit support line: 1-800-784-8669 (1-800-QUIT-NOW)
TTY: 1-800-332-8615
Web site: www.cdc.gov/tobacco
The quit support line offers information on smoking and health as well as help
with quitting. Languages and range of services vary by your state of residence
National Cancer Institute
Free tobacco line: 1-877-448-7848 (1-877-44U-QUIT) (also available in Spanish)
Direct tobacco Web site: www.smokefree.gov
Quitting information, quit-smoking guide, and counseling are offered, as well as
referral to state telephone-based quit programs (if needed for special services)

American Heart Association
Toll-free number: 1-800-242-8721 (1-800-AHA-USA-1)
Web site: www.americanheart.org
Quitting tips and advice can be found at www.everydaychoices.org or by calling
1-866-399-6789
Environmental Protection Agency (EPA)
Telephone: 202-272-0167
Web site: www.epa.gov/
Has advice on how to protect children from secondhand smoke, a Smoke-free
Homes Pledge, and other tobacco-related materials on the direct Web site,
www.epa.gov/smokefree, or at 1-866-766-5337 (1-866-SMOKE-FREE)
American Lung Association
Toll-free number: 1-800-548-8252
Web site: www.lungusa.org
Printed quit materials are available, some in Spanish. Also offers a low cost quit-
smoking program “Freedom from Smoking Online” at www.ffsonline.org; a free
version is available, too
*Inclusion on this list does not imply endorsement by the American Cancer Society.
No matter who you are, we can help. Contact us anytime, day or night, for information
and support. Call us at 1-800-227-2345 or visit www.cancer.org.
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Last Medical Review: 10/4/2012
Last Revised: 10/18/2012
2012 Copyright American Cancer Society

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