Hep intro
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This document summarizes epidemiology and prevention of viral hepatitis A through E. It provides overviews of the historical perspectives and types of hepatitis viruses. Key points include: - Hepatitis A-E viruses differ in their sources (feces to blood), transmission routes (fecal-oral to percutaneous), ability to cause chronic infection, and prevention methods (immunization to safe drinking water). - In the US from 1982-1993, hepatitis A accounted for 47% of acute viral hepatitis cases, hepatitis B was 34%, and hepatitis C was 16%. - Estimated annual acute infections in the US are 125-200,000 for hepatitis A; 140-320,000 for hepatitis B; 35-180
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Hep intro
- 1. Epidemiology and Prevention of Viral Hepatitis A to E: Hepatitis Branch Centers for Disease Control and Prevention An Overview
- 2. Viral Hepatitis - Historical Perspective AA““Infectious”Infectious” ““Serum”Serum” ViralViral hepatitishepatitis EntericallyEnterically transmittedtransmitted ParenterallyParenterally transmittedtransmitted F, G,F, G, ? other? other EE NANBNANB BB DD CC
- 3. Viral Hepatitis - Overview A B C D E Source of virus feces blood/ blood-derived body fluids blood/ blood-derived body fluids blood/ blood-derived body fluids feces Route of transmission fecal-oral percutaneous permucosal percutaneous permucosal percutaneous permucosal fecal-oral Chronic infection no yes yes yes no Prevention pre/post- exposure immunization pre/post- exposure immunization blood donor screening; risk behavior modification pre/post- exposure immunization; risk behavior modification ensure safe drinking water Type of Hepatitis
- 4. 47% 34% 16% 3% Hepatitis A Hepatitis B Hepatitis C Hepatitis Non-ABC Source: CDC Sentinel Counties Study on Viral Hepatitis Acute Viral Hepatitis by Type, United States, 1982- 1993
- 5. Estimates of Acute and Chronic Disease Burden for Viral Hepatitis, United States HAV HBV HCV HDV Acute infections (x 1000)/year* 125-200 140-320 35-180 6-13 Fulminant deaths/year 100 150 ? 35 Chronic infections 0 1-1.25 million 3.5 million 70,000 Chronic liver disease deaths/year 0 5,000 8-10,000 1,000 * Range based on estimated annual incidence, 1984-1994.
- 6. Estimates of Acute and Chronic Disease Burden for Viral Hepatitis, United States HAV HBV HCV HDV Acute infections (x 1000)/year* 125-200 140-320 35-180 6-13 Fulminant deaths/year 100 150 ? 35 Chronic infections 0 1-1.25 million 3.5 million 70,000 Chronic liver disease deaths/year 0 5,000 8-10,000 1,000 * Range based on estimated annual incidence, 1984-1994.