This document provides guidance on ICD-10-CM coding for common upper extremity conditions and injuries involving different body systems. It lists codes for pain in specific areas of the upper extremity, pain and stiffness in joints like the shoulder and elbow, and codes for osteoarthritis based on location and type. Additional codes are presented for common shoulder conditions, epicondylitis, and carpal tunnel syndrome. Injury codes ranging from S40-S69 are provided based on the location of the injury in the upper extremity. CPT codes relevant to the hand, wrist, and blood vessels are also listed.