The Periyar River in Kerala, India has become severely polluted due to industrial, agricultural, and domestic waste. Over 247 chemical industries dump toxic wastewater into the river, contaminating the soil and water with heavy metals and chemicals. As a result, aquatic life in the river and connected water bodies has been devastated. The pollution has also negatively impacted the health of local communities. Sand mining and radioactive waste storage further degrade the river ecosystem. Efforts are needed from industries, local authorities, farmers, and citizens to better treat wastes and raise awareness to restore the river's water quality.