Introduction to Pathology and how to describe a Lesion
- 1. LECTURE NO.1 Veterinary General Pathology 301 Practical Class
- 2. Learning Outcomes • By the end of the lecture you should be able to: • Define Pathology in two ways • Define General Pathology • Discuss about the Morphological Changes • Explain lesion and types of the Lesion • Define Gross examination and Histopathology • How to describe the Lesion in Gross examination
- 3. Introduction to Pathology •Pathology: • Pathology is the study of Disease. • Pathos – suffering, disease • Logos – study Disease? *loss of ease *a departure from a normal state The better we understand the disease, the better we can diagnose & treat it
- 4. What‘s normal (When Body At Ease) Anatomy Physiology Histology Biochemistry Genetics Health is a state of an individual living in complete harmony with his environment.
- 5. Pathology is the study of molecular, biochemical, functional, & morphological changes in cells, tissues, or organs in response to an INJURY Let’s define again Cell damage is cell injury
- 6. Agents that cause things to go wrong/ injury Trauma Microbial Nutritious Genetic Chemicals Parasitic
- 8. Pathology General Pathology Concerned with the basic reactions of cells and tissues to injurious stimuli Systemic Pathology The application of these basic reactions to the various body systems, or to various specific diseases
- 9. Pathology Clinical Pathology It includes certain laboratory methods which help in making the diagnosis e.g. urine examination, blood examination Necropsy & meat inspection Postmortem examination of animals. To determine the health of animals both prior to death (ante mortem) and after death (post mortem)
- 10. Pathology covers Four aspects of a disease process Etiology ( cause of disease) Pathogenesis Morphological Changes (Lesions) Clinical significant / Functional Consequence General/Systemic Pathology Practical
- 11. Morphological Changes (Lesion) The structural alterations in cells or tissues A lesion is any damage or abnormal change in the tissue structure of an organism, usually caused by disease Morphology study of forms and structures
- 12. Types of Lesion Macroscopic or Microscopic morphological alteration occurring in the tissue structure or function as the result of injury Macroscopic or Gross Lesions Can see through the naked eye Gross Examination Examination of tissue without the help of a microscope Microscopic or histopathology Lesions Can see through a microscope Histopathology Study of diseases tissue under a microscope Let’s define again the lesion
- 17. Multifocal Lesions Aborted Pig fetus Lamb’s Liver
- 33. Describe the lesions in liver
- 34. Describe the lesions in Proventriculus and Gizzard of the bird
- 35. Revisiting Learning Outcomes • By the end of the lecture you should be able to: • Define Pathology in two ways yes/no • Define General Pathology yes/no • Discuss about the Morphological Changes yes/no • Explain lesion and types of the Lesion yes/no • Define Gross examination and Histopathology yes/no • How to describe the Lesion in Gross examination yes/no