The TDR Targets Database, an introduction.

The TDR Targets Database is an online resource that integrates genomic information relevant for drug discovery on pathogens that cause human diseases. It covers organisms like Plasmodium falciparum (malaria), Mycobacterium tuberculosis (tuberculosis), Trypanosoma brucei (African trypanosomiasis), and others. The database allows users to search for drug targets in these pathogens based on criteria like functional category, phylogenetic distribution, and essentiality. It provides detailed information on resulting target genes, including pathways, structural models, orthologs, essentiality data, druggability, and associated compounds.