Karl Kjer, an award-winning molecular phylogeneticist, highlights the importance of pursuing a career in science as a means to explore curiosity and contribute to societal well-being amidst challenges such as anti-science sentiments. He emphasizes the need for aspiring scientists to seek mentorship from established professionals to navigate their career paths. Kjer’s notable achievements include co-founding the 1,000 insect transcriptome evolution initiative and mentoring future scientists.