Randy Pausch gave a talk about achieving his childhood dreams and enabling the dreams of others. Some of his dreams included being in zero gravity, playing in the NFL, being an author and Captain Kirk. Through hard work and perseverance, he was able to fulfill some dreams and learn lessons from others. He helped create programs like the Entertainment Technology Center and Alice to help students pursue their dreams. Some key lessons included finding mentors, working hard, being grateful and helping others achieve their dreams.