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LINIMENTS
Liniments

 Liniments are solutions or mixtures of various substances
  in oil, alcoholic solutions of soap, or emulsions and may
  contain suitable antimicrobial preservatives.
 These preparations that may be liquid or semi-liquid are
  intended for external application and should be so
  labeled.
 They are rubbed onto the affected area; because of
  this, they were once called embrocation. They are
  applied with friction and rubbing of the skin, the oil or
  soap base providing for ease of application and massage.
General uses of Liniments

 Antipruritic - used to relieve itching
 Astringents - causes biological tissue to contract
 Emollients - products that soften skin or treat dry skin
 Analgesics
 Rubefacient-Substance that causes redness (Rubar)
 Counterirritant- an agent applied locally to produce
  superficial inflammation with the object of reducing
  inflammation in deeper adjacent structures.
Liniments

 Only suitable for external use
 That are emulsions or that contain insoluble matter must
  be shaken thoroughly before use
How Liniments are prepared

 The vehicle should be selected for the type of action
  desired (rubefacient, counterirritant, massage) and also
  on the solubility of the desired components in the
  various solvents
 Prepared in the same manner as solutions, emulsions, or
  suspensions
There are two types of Liniments:

Alcoholic liniments            Oleaginous liniments.


 used generally for their      Milder in their action but
  rubefacient, counterirrita     is more useful when
  nt mildly astringent, and      massage is required
  penetrating effects           less irritating to the
 penetrate the skin more        skin, depending on their
  readily than do those          ingredients
  with an oil base.             may function solely as
                                 protective coatings.
There are two types of Liniments:

Alcoholic liniments            Oleaginous liniments.


 used generally for their      Solvent may be a fixed
  rubefacient, counterirrita     oil (almond oil, peanut
  nt mildly astringent, and      oil, sesame
  penetrating effects            oil, cottonseed oil) or
 penetrate the skin more        volatile substance (
  readily than do those          wintergreen
  with an oil base.              oil, turpentine) or a
                                 combination of fixed and
                                 volatile oil
Liniments:

 Liniments should NOT be applied to skin that is
  bruised/Broken because excessive irritation might occur.
  This application should be marked for “external use
  only”
 Dermatologist prescribe products of this type but only
  those containing the rubefacients are advertised
  extensively and used by consumers for treating minor
  muscular aches and pains.
Examples of Liniments

 Compound Calamine Liniment
 Efficascent oil
 White Liniment
Examples of Liniments

 White liniments
Formulation


Material           Original formular   catergory            Uses
Oleic Acid         85mL
Turpentine Oil     250mL               Corrective           Counterirritant
Ammonia solution   45mL                Alkalinizing agent   provide alkaline
                                                            medium
Ammonium           12.5g               Active ingredient
Chloride
Purified water     625ml               Diluent              Primary solvent
Procedure

1.   Mix oleic Acid with turpentine oil
2.   Dilute ammonia solution with 45ml of water, previously
     warmed.
3.   Add to the oily solution and shake to form emulsion
4.   Dissolve Ammonium Chloride in water
5.   Add the emulsion.
COMPOUND CALAMINE LINIMENT

 USE:
  = Soothing application used to treat the discomfort of
  dermatitis and eczema.
 APPEARANCE:
 = Yellow suspension

    Synonym: Compound Calamine liniment, Applicatio Calamine
     Composita
EFFICASCENT OIL

 USE:
  = For Temporary relief of minor aches and pains of muscles
  and joints associated with:
 Simple Backache
 Arthritis
 Strains
 Sprains
 Counterirritant
 APPEARANCE:
  = green clear liquid
 Synonym = methylsalicylate camphor

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Liniments Presentation

  • 2. Liniments  Liniments are solutions or mixtures of various substances in oil, alcoholic solutions of soap, or emulsions and may contain suitable antimicrobial preservatives.  These preparations that may be liquid or semi-liquid are intended for external application and should be so labeled.  They are rubbed onto the affected area; because of this, they were once called embrocation. They are applied with friction and rubbing of the skin, the oil or soap base providing for ease of application and massage.
  • 3. General uses of Liniments  Antipruritic - used to relieve itching  Astringents - causes biological tissue to contract  Emollients - products that soften skin or treat dry skin  Analgesics  Rubefacient-Substance that causes redness (Rubar)  Counterirritant- an agent applied locally to produce superficial inflammation with the object of reducing inflammation in deeper adjacent structures.
  • 4. Liniments  Only suitable for external use  That are emulsions or that contain insoluble matter must be shaken thoroughly before use
  • 5. How Liniments are prepared  The vehicle should be selected for the type of action desired (rubefacient, counterirritant, massage) and also on the solubility of the desired components in the various solvents  Prepared in the same manner as solutions, emulsions, or suspensions
  • 6. There are two types of Liniments: Alcoholic liniments Oleaginous liniments.  used generally for their  Milder in their action but rubefacient, counterirrita is more useful when nt mildly astringent, and massage is required penetrating effects  less irritating to the  penetrate the skin more skin, depending on their readily than do those ingredients with an oil base.  may function solely as protective coatings.
  • 7. There are two types of Liniments: Alcoholic liniments Oleaginous liniments.  used generally for their  Solvent may be a fixed rubefacient, counterirrita oil (almond oil, peanut nt mildly astringent, and oil, sesame penetrating effects oil, cottonseed oil) or  penetrate the skin more volatile substance ( readily than do those wintergreen with an oil base. oil, turpentine) or a combination of fixed and volatile oil
  • 8. Liniments:  Liniments should NOT be applied to skin that is bruised/Broken because excessive irritation might occur. This application should be marked for “external use only”  Dermatologist prescribe products of this type but only those containing the rubefacients are advertised extensively and used by consumers for treating minor muscular aches and pains.
  • 9. Examples of Liniments  Compound Calamine Liniment  Efficascent oil  White Liniment
  • 10. Examples of Liniments  White liniments
  • 11. Formulation Material Original formular catergory Uses Oleic Acid 85mL Turpentine Oil 250mL Corrective Counterirritant Ammonia solution 45mL Alkalinizing agent provide alkaline medium Ammonium 12.5g Active ingredient Chloride Purified water 625ml Diluent Primary solvent
  • 12. Procedure 1. Mix oleic Acid with turpentine oil 2. Dilute ammonia solution with 45ml of water, previously warmed. 3. Add to the oily solution and shake to form emulsion 4. Dissolve Ammonium Chloride in water 5. Add the emulsion.
  • 13. COMPOUND CALAMINE LINIMENT  USE: = Soothing application used to treat the discomfort of dermatitis and eczema.  APPEARANCE: = Yellow suspension  Synonym: Compound Calamine liniment, Applicatio Calamine Composita
  • 14. EFFICASCENT OIL  USE: = For Temporary relief of minor aches and pains of muscles and joints associated with:  Simple Backache  Arthritis  Strains  Sprains  Counterirritant  APPEARANCE: = green clear liquid  Synonym = methylsalicylate camphor