Liver Function Test | A must needed precautionary act
- 1. Liver Function Test Happy is Healthy
- 2. Liver Function Test • Liverfunctiontesthelpstodeterminethehealthofyourliverby measuringthelevelofproteins,liverenzymes,orbilirubinin yourblood.
- 3. When do you need a Liver Function Test??? • Ifyouhavesymptoms,toscreenforanypotentialliverproblemsor infectionsaffectingtheliversuchashepatitisA,hepatitisBandhepatitisC. • Toaidinthediagnosisofotherconditionssuchasgallstones. • Whenyouhaveliverdisease,tomonitortheprogressionandseverityofthe disease,andtodeterminehowwellatreatmentisworking • Tomonitorsideeffects,ifyouaretakingprescription,ornon-prescription medicinesthatcanaffectyourliverfunction.
- 4. Why do you need a Liver Function Test: • Removingcontaminantsfromyourblood • Convertingnutrientsfromthefoodsyoueat • Storingmineralsandvitamins • Regulatingbloodclotting • Producingproteins,enzymes,andbile • Makingfactorsthatfightinfection • Removingbacteriafromyourblood • Processingsubstancesthatcouldharmyourbody • Maintaininghormonebalances
- 5. Common Tests for Liver Function Test • AlanineTransaminase(SGPT) • AlkalinePhosphatase • Bilirubin–(Direct,Indirect,Total) • GammaGlutamy|Transferase(GGT) • Protein-Total • SerumAlbumin • SerumGlobulin • AspartateAminotransferase(SGOT) • SerumAlbumin/GlobulinRatio
- 6. Alanine Transaminase (SGPT) • Alanine Transaminase isusedbyyourbodytometabolizeprotein • Iftheliverisdamagedornotfunctioningproperly,AlanineTransaminase isreleasedintotheblood. • ThiscausesAlanine Transaminase levelstoincrease. • AhighresultonthistestcanbesignofLiverdamage. • Doctorwillprescribeyouthistestifyouhavesymptomslike:Vomiting, Weakness,Extremetiredness,Dark-coloredUrine,Itchyskin,orJaundice
- 7. Alkaline Phosphate : • AlkalinePhosphate(ALP)isanenzyme foundinBones,bileductsandLiver. • AnAlkalinePhosphateistypicallyorderedincombinationwithseveralother tests. • HighlevelofAlkalinePhosphatemayindicateliverdamage,blockageofthebile ducts,orabonedisease. • Childrenandadolescents mayhaveelevated levelsofALPbecausetheirbonesare growing.Pregnancy canalsoraiseALPlevels. • NormalrangeforALPIs(45–115)U/L. • LowlevelsofALPcanoccurfollowingabloodtransfusionorheartbypass surgery. • LowlevelofALPcanresultfromazincdeficiency ormalnutrition.
- 8. Aspartate aminotransferase (SGOT) : • Aspartateaminotransferaseisanenzymefoundinseveralpartsofyourbody including,theheart,liverandmuscles. • SinceAspartateaminotransferaselevelsaren’tspecificforliverdamage,it’s usuallymeasured togetherwithAlanineTransferase tocheckliverproblems. • Whenliverisdamaged,Aspartatetransferaseisreleasedintothebloodstream. • AhighlevelofAspartateaminotransferasetestmightindicateaproblemwith liverormuscle. • Thenormalrangeforthistestis8-48U/L.
- 9. Bilirubin test : • Bilirubinisawasteproductfrombreakdownofredbloodcells.It’sordinarilyprocessed byliver. • Itpassesthroughtheliverbeforebeingexcretedthroughyourstool. • Adamagedlivercan’tproperlyprocessBilirubin,sothisleadstoanabnormallyhigh levelofBilirubinintheblood. • Ahighresultonthebilirubintestindicatesthattheliverisn’tfunctioning properly • Henormalrangeforbilirubinis0.1–1.2mg/dL a) IndirectBilirubin:Bilirubinnotattachedtoglucuronic. b) TotalBilirubin:Allthebilirubininyourbloodtogether.(0.3-1.9mg/dL)
- 10. Serum Albumin test : • Albuministhemainproteinmadebyyourliver.Itperformsmanyimportantbodily functions,Suchas: Stopfluidfromleakingoutofyourbloodvessels. Nourishesyourtissues. Transportshormones,vitaminsandothersubstancesthroughout yourbody. • Analbumintestmeasureshowwellyourliverismakingthisparticularprotein.Alow resultonthistestindicatesthatyourliverisn’tfunctioningproperly. • Thenormalrangeforalbuminis(3.5–5.0)gramsperdeciliter(g/dL).
- 11. Gamma-Glutamyl Transferase(GGT): • TheGamma-glutamyltranferasetestmeasurestheamountofenzymeinyour blood. • Sinceenzymesaremoleculesthatarenecessaryforchemicalreactioninyour body,SoGamma-glutamyltransferasefunctionsinthebodyasatransport moleculehelpingtomoveothersmoleculesaroundthebody. • Itplaysasignificantroleinhelpingthelivermetabolizedrugs&othertoxins. • Thistestbeingprescribedbydoctorifhesuspectsyourliverdamagedueto heavyalcoholuseoranytoxicsubstanceslikedrugs/poison.
- 12. Serum Globulin test : • Globulinsareagroupofproteinsinyourblood.Theyaremadeinyourliverbyyour immunesystem.Globulinsplayanimportantroleinliverfunction,bloodclotting,and fightinginfection. • Atotalproteintestmaybeincludedinaseriesofteststocheckhowwellyourliveris working. • Globulintestsarebloodtests.Duringabloodtest,ahealthcareprofessionalwilltakea bloodsamplefromaveininyourarm,usingasmallneedle. • Lowglobulinlevelscanbeasignofliverorkidneydisease. • Highglobulinlevelsmayalsoindicatecertaintypesofcancer,suchasmultiple myeloma,Hodgkin'sdisease.
- 13. COST@ LIVER FUNCTION TEST Market Price (in Gen.) • Price for Multiple cities in India @Rs.1000/-INR only @BookMyScans • Price in Multiple cities in India @Rs.400/- • Package includes (11 tests) : Serum Albumin / Globulin Ratio Alkaline Phosphatase Bilirubin - Direct Bilirubin - Indirect Bilirubin - Total Gamma Glutamy|Transferase (GGT) Protein - Total Serum Albumin Serum Globulin Aspartate Aminotransferase (SGOT) Alanine Transaminase (SGPT)