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Testing of long term memory:

          Dr.Roopchand.PS
      Senior Resident Academic
      Department of Neurology
          TDMC, Alappuzha
Memory:
• Ability of the brain to store and retrieve
  information.
  – Explicit memory: conscious, intentional
    recollection of an event or item of information.
  – Includes – immediate, short term and long term
    memories.
  – Implicit memory: Unconscious retention in
    memory, as evidenced by the effect of a previous
    experience or previously encountered information
    on current thoughts or actions.
  – Includes – motor memory.
Long term memory




  Procedural               Declarative
  memories                 memories
“Knowing how”            “knowing that”




                                    Episodic memories
           Semantic memories
                                            ‘Personal
          ‘general knowledge’
                                          recollection’
Contents of long term memory:
• Procedural memory:
  – Memories for performance of action or skills
  – “knowing how”
• Declarative memory:
  – Memories of facts, rules, concepts and events;
    includes semantic and episodic memory.
  – “knowing that”
• Semantic memory:
  – General knowledge, including facts, rules,
    concepts and propositions.
• Episodic memories:
  – Personally experienced events and the contexts in
    which they occurred.
How to Remember things!!!
• Maintenance rehearsal: rote repetition of
  material in order to maintain its availability in
  memory.
• Elaborative rehearsal: association of new
  information with already stored knowledge
  and analysis of new information to make it
  memorable.
Anatomic correlate of long term
              memory:
• Thought to reside in multiple cortical region.
  – Visual association cortex for visual memory.
  – Temporal cortex for auditory memory.
  – Left lateral temporal cortex : knowledge of word
    meaning.
• fMRI studies support this concept.
• Memory can be retrieved with out the
  hippocampal system from neo cortex.
Testing:


• Personal information:
  – Where were you born?
  – School information
  – Vocation history
  – Family information
• Historic Facts:
  – Always consider patients education level.
  – Ask about common historic facts, if possible
    sequentially.
Registration vs Retrieval?



• A clue is the clue to it.
Procedural memory testing:
• Pursuit rotor task:
• simple pure visual-motor tracking test that has
  consistent results within age groups.
• measurement of procedural memory as well as
  demonstrates the participant's fine-motor skills.
• Amnesic participants show no impairment in this
  motor task when tested at later trials.
• It does however seem to be affected by lack of
  sleep and drug use
Long term memory testing
• Serial reaction time task:
  – having participants retain and learn procedural
    skills that assess specific memory for procedural-
    motor skill.
  – Patiets with Alzheimer's disease and amnesia
    demonstrate a long retention time which indicates
    that they are able to retain the skill and
    demonstrate effective performance of the task at
    a later point in time.
• Mirror tracing task:
  – looks at the integration of the senses .
  – it is a visual motor test where the participants
    learn a new motor skill involving hand-eye
    coordination.
  – Drawing the image is the work of your procedural
    memory.
  – once you figure out how to draw the image in the
    mirror you have little difficulty the second time.
  – Alzheimer’s disease are not able to recall the skills
    acquired in a mirror tracing task, but they acquire
    the procedural performance ability regardless
Long term memory testing

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Long term memory testing

  • 1. Testing of long term memory: Dr.Roopchand.PS Senior Resident Academic Department of Neurology TDMC, Alappuzha
  • 2. Memory: • Ability of the brain to store and retrieve information. – Explicit memory: conscious, intentional recollection of an event or item of information. – Includes – immediate, short term and long term memories. – Implicit memory: Unconscious retention in memory, as evidenced by the effect of a previous experience or previously encountered information on current thoughts or actions. – Includes – motor memory.
  • 3. Long term memory Procedural Declarative memories memories “Knowing how” “knowing that” Episodic memories Semantic memories ‘Personal ‘general knowledge’ recollection’
  • 4. Contents of long term memory: • Procedural memory: – Memories for performance of action or skills – “knowing how” • Declarative memory: – Memories of facts, rules, concepts and events; includes semantic and episodic memory. – “knowing that”
  • 5. • Semantic memory: – General knowledge, including facts, rules, concepts and propositions. • Episodic memories: – Personally experienced events and the contexts in which they occurred.
  • 6. How to Remember things!!! • Maintenance rehearsal: rote repetition of material in order to maintain its availability in memory. • Elaborative rehearsal: association of new information with already stored knowledge and analysis of new information to make it memorable.
  • 7. Anatomic correlate of long term memory: • Thought to reside in multiple cortical region. – Visual association cortex for visual memory. – Temporal cortex for auditory memory. – Left lateral temporal cortex : knowledge of word meaning. • fMRI studies support this concept. • Memory can be retrieved with out the hippocampal system from neo cortex.
  • 8. Testing: • Personal information: – Where were you born? – School information – Vocation history – Family information
  • 9. • Historic Facts: – Always consider patients education level. – Ask about common historic facts, if possible sequentially.
  • 10. Registration vs Retrieval? • A clue is the clue to it.
  • 11. Procedural memory testing: • Pursuit rotor task: • simple pure visual-motor tracking test that has consistent results within age groups. • measurement of procedural memory as well as demonstrates the participant's fine-motor skills. • Amnesic participants show no impairment in this motor task when tested at later trials. • It does however seem to be affected by lack of sleep and drug use
  • 13. • Serial reaction time task: – having participants retain and learn procedural skills that assess specific memory for procedural- motor skill. – Patiets with Alzheimer's disease and amnesia demonstrate a long retention time which indicates that they are able to retain the skill and demonstrate effective performance of the task at a later point in time.
  • 14. • Mirror tracing task: – looks at the integration of the senses . – it is a visual motor test where the participants learn a new motor skill involving hand-eye coordination. – Drawing the image is the work of your procedural memory. – once you figure out how to draw the image in the mirror you have little difficulty the second time. – Alzheimer’s disease are not able to recall the skills acquired in a mirror tracing task, but they acquire the procedural performance ability regardless