This document summarizes several nonparametric statistical tests that do not rely on assumptions about the population distribution, including the sign test, Wilcoxon signed-rank test, median test, Mann-Whitney test, Kolmogorov-Smirnov goodness-of-fit test, and Kruskal-Wallis one-way analysis of variance. It provides details on the theoretical background, test statistics, assumptions, and procedures for the sign test for single samples and paired data. An example application of the paired sign test to a dental study is shown.