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Using the ADOS Severity Metric to Evaluate a Behavioral Intervention in a Large Public School District Colleen M. Harker; Erica M. Reisinger; Andrea D. Sherman; Ming Xie, MS; Sujie Shin, MA; David S. Mandell, ScD University of Pennsylvania School of Medicine; Penn/CHOP Center for Autism Research Background Though intended as a diagnostic tool, the ADOS is increasingly used as an outcome measure.  Gotham et al. (2009) developed a severity metric* for longitudinal cross-module comparisons of symptom severity over time. The severity metric has not been used to measure intervention outcomes.   152 children were assessed as part of an  intervention study in the School District of Philadelphia. Students were administered the ADOS and  DAS at the beginning and end of the school year to measure changes over time in  communication, socialization and cognitive functioning.  Teachers completed the SRS and PDDBI at  the beginning and end of the school year  to measure social impairment and behaviors associated with autism.  Results indicate that the 2007 revised ADOS algorithm is more highly correlated with the DAS, SRS, and PDDBI than the 2000 ADOS algorithm. Including the Restricted & Repetitive Behaviors score in the raw total as the revised algorithm does, leads to higher correlation with outcome measures.  16.5% of the students moved up a module between baseline and outcome, which appears to inflate symptom severity scores.  The severity metric appears promising  as an outcome measure in a behavioral intervention study. The severity metric needs to be more sensitive to module change as a measure of symptom severity change over time.  Results p<0.05 for all correlations DAS scores are reverse scored * Severity Metric = Maps the 2007 revised ADOS algorithm raw totals onto calibrated severity scores based on age & ADOS module ** Calibrated ADOS Symptom Severity Score = 1-10 score calculated using the severity metric  *** 2007 Revised ADOS Algorithm = Social Affect (Communication + Reciprocal Social Interaction) + Restricted & Repetitive Behaviors **** 2000 ADOS Algorithm = Communication + Reciprocal Social Interaction To examine the utility of the ADOS severity metric as an outcome measure in a 9-month behavioral intervention study. To determine how scores on the 2000 ADOS algorithm**** and 2007 revised ADOS algorithm*** correlate with outcome  measures.  Objectives Methods Discussion

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Using the Ados Severity Metric to Evaluate a Behavioral Intervention in a Large Public School District 5.14.10

  • 1. Using the ADOS Severity Metric to Evaluate a Behavioral Intervention in a Large Public School District Colleen M. Harker; Erica M. Reisinger; Andrea D. Sherman; Ming Xie, MS; Sujie Shin, MA; David S. Mandell, ScD University of Pennsylvania School of Medicine; Penn/CHOP Center for Autism Research Background Though intended as a diagnostic tool, the ADOS is increasingly used as an outcome measure. Gotham et al. (2009) developed a severity metric* for longitudinal cross-module comparisons of symptom severity over time. The severity metric has not been used to measure intervention outcomes. 152 children were assessed as part of an intervention study in the School District of Philadelphia. Students were administered the ADOS and DAS at the beginning and end of the school year to measure changes over time in communication, socialization and cognitive functioning. Teachers completed the SRS and PDDBI at the beginning and end of the school year to measure social impairment and behaviors associated with autism. Results indicate that the 2007 revised ADOS algorithm is more highly correlated with the DAS, SRS, and PDDBI than the 2000 ADOS algorithm. Including the Restricted & Repetitive Behaviors score in the raw total as the revised algorithm does, leads to higher correlation with outcome measures. 16.5% of the students moved up a module between baseline and outcome, which appears to inflate symptom severity scores. The severity metric appears promising as an outcome measure in a behavioral intervention study. The severity metric needs to be more sensitive to module change as a measure of symptom severity change over time. Results p<0.05 for all correlations DAS scores are reverse scored * Severity Metric = Maps the 2007 revised ADOS algorithm raw totals onto calibrated severity scores based on age & ADOS module ** Calibrated ADOS Symptom Severity Score = 1-10 score calculated using the severity metric *** 2007 Revised ADOS Algorithm = Social Affect (Communication + Reciprocal Social Interaction) + Restricted & Repetitive Behaviors **** 2000 ADOS Algorithm = Communication + Reciprocal Social Interaction To examine the utility of the ADOS severity metric as an outcome measure in a 9-month behavioral intervention study. To determine how scores on the 2000 ADOS algorithm**** and 2007 revised ADOS algorithm*** correlate with outcome measures. Objectives Methods Discussion