Predictive Risk 2012: Context


Predictive R
13 June 2012


Martin Bardsley
Head of Research
Nuffield Trust



                                © Nuffield Trust
Predictive modelling

• BMJ in paper* in 2002 showed Kaiser Permanente in California
  seemed to provide higher-quality healthcare than the NHS at a
  lower cost. Kaiser identify high risk people in their population and
  manage them intensively to avoid admissions
• Modelling aims to identify people at risk of future event
• Relies on exploiting existing information
   +ve: systematic; not costly data collections; fit into existing systems
   -ve: information collected may not be predictive
• Use pseudonymous, person-level data
• In health sector a number of predictive models are available
  e.g. PARR++ and the combined model.
•   *Getting more for their dollar: a comparison of the NHS with California's Kaiser Permanente BMJ 2002;324:135-143

                                                                                                                 © Nuffield Trust
Uneven distribution of costs



                               The proportion of total costs
                               spent on patients with
                               category of annual costs
                               (area of shape) with the
                               proportion of all patients in
                               annual cost band (dots)

                               Around 3% of patients are
                               responsible for nearly half the
                               total patient costs



                                                                 © Nuffield Trust
Predicting admissions in advance
Change in average number of emergency bed days




            Predictive
            models try to
            identify
            people here




                                                 © Nuffield Trust
Health and social care event timeline




                                        © Nuffield Trust
Patterns in routine data to identify high-risk people next year




                                                                  © Nuffield Trust
Distribution of Combined Model risk scores
Importance of risk adjustment

 Very high risk
                  Top 0.5%                          Top 10%
 High risk
 Moderate risk
                     0.5% - 5%
 Low risk
                        5% - 20%
                                                          10% - 45%


                              20% - 100%
                                                               45% - 85%

                                                                  85% - 100%

         General population          WSD participants –
                                     receiving telehealth or telecare
                                                                      © Nuffield Trust
Applications of predictive risk


• Case finding for people at high risk of admission seen as
  increasingly important for people with LTCs and complex
  conditions
• Evaluation and risk adjustment eg WSD
• Predicting future costs eg work on resource allocation


Related: Scope to make the most of linked data sets in
         describing care pathways


                                                              © Nuffield Trust
Choosing the predictive model bit

• What event should we be aiming to predict?
• What models and tools are available?
• What data do I need and how often?
• How often do predictive models need to be run?
• How accurate is the model?
• How much does it cost?




                                                   © Nuffield Trust
(1) Predictive tool = Predictive model + Software platform

Inputs
                                       Processing
 Inpatient data

 Outpatient               Tools to                    Predictive
                          organise                    model
 GP data                  input data

 Population data




                   Presentation and         Outputs
                                                       Patient lists with risk
                   analysis tools                      score
                   -Gaps in care
                   -Priority lists




                                              Users                              © Nuffield Trust
Age distribution and mean risk scores within a diagnostic
categories




                                                            © Nuffield Trust
Testing for gaps in care




                           © Nuffield Trust
(2) Key metrics for performance of a model (PPV and
sensitivity)

                         100%
                                                                  Positive predictive value
                         90%
                                                                  When the model says high risk how often
                         80%                                      is it right?
   Sensitivity (Brown)




                         70%
      PPV (blue),




                         60%

                         50%

                         40%
                                                                                 Sensitivity
                         30%                                                     What proportion of all
                         20%                                                     events will the model
                                                                                 detect?
                         10%

                          0%
                                0   10     20     30     40      50     60      70     80     90   100
                                     Threshold value (lower bound of defined 'high risk' group)
  Pooled 4-site 1k model                                                                                 © Nuffield Trust
Typical performance of models – predicting events next
year

Predicting ...                  How many        What proportion of all
                                positives are   events are found
                                correct (PPV)   (Sensitivity)
Readmission based on prior         50%-75%             30-50%
admissions eg PARR
Admission to hospital from a        20-50%             5%-15%
general population
As above but just for highest       70-80%              5-10%
risk groups (top 10%)
Changes in social care use          20-50%              5-15%




                                                                         © Nuffield Trust
(3) Emerging market in England

• August 2011, the Department of Health announced that it
  had no plans to commission national updates of the latest
  Patients at Risk of Re-hospitalisation tool (PARR++) or the
  Combined Predictive Model
• Range of new/established commercial organisation
  developing risk tools
• Creation of new commissioning groups and new markets
• Increasing ease of accessing GP data
• Continuing financial pressures and the search for ways to
  reduce emergency hospital care.

                                                                © Nuffield Trust
Examples of case finding models available (with or
without software platforms)

      SPARRA                             PARR (++)
      SPARRA MD                          Combined Predictive Model

      PRISM                              PEONY
      AHI Risk adjuster                  LACE
      ACGs (Johns Hopkins)               MARA (Milliman Advanced Risk Adjuster)

      DxCGs (Verisk)                     Dr Foster Intelligence
      SPOKE (Sussex CPM)                 QResearch models eg QD score
      LACE
                                         RISC
    Variants on basic admission/readmission predictions:
    Short term readmissions                Social care
    Condition specific tools                Costs                                 © Nuffield Trust
(4) The model by itself doesn't change anything...
Choosing an application

• Which people should I target?
• What interventions should we use?
• Who will use it and how? What clinical staff need to see
  results?
• Will some patients benefit more than others?
• When can I expect to see a return on investment?




                                                             © Nuffield Trust
Summary

• Predictive modelling is a practical case finding tool for
  identifying high risk patients
• Growing market for predictive models – extending beyond
  simple annual predictions of readmissions
• Ability to look at linked data valuable for other analyses
• Technical details of model performance is important – but
  so how is the way the model is implemented
•   We hope today's conference will help you learn more about
    peoples’ experience of using these models.


                                                                © Nuffield Trust
The day ahead

• A review around the UK
• Examples of different ways that risk models have been
  applied in the NHS
• A view from outside the UK Germany and US.
• Developments in modelling
• Open session...share your experiences.




                                                          © Nuffield Trust
www.nuffieldtrust.org.uk


Sign-up for our newsletter
www.nuffieldtrust.org.uk/newsletter/login.aspx


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                                                 © Nuffield Trust

                                                 © Nuffield Trust

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Martin Bardsley: Predictive risk 2012: context

  • 1. Predictive Risk 2012: Context Predictive R 13 June 2012 Martin Bardsley Head of Research Nuffield Trust © Nuffield Trust
  • 2. Predictive modelling • BMJ in paper* in 2002 showed Kaiser Permanente in California seemed to provide higher-quality healthcare than the NHS at a lower cost. Kaiser identify high risk people in their population and manage them intensively to avoid admissions • Modelling aims to identify people at risk of future event • Relies on exploiting existing information +ve: systematic; not costly data collections; fit into existing systems -ve: information collected may not be predictive • Use pseudonymous, person-level data • In health sector a number of predictive models are available e.g. PARR++ and the combined model. • *Getting more for their dollar: a comparison of the NHS with California's Kaiser Permanente BMJ 2002;324:135-143 © Nuffield Trust
  • 3. Uneven distribution of costs The proportion of total costs spent on patients with category of annual costs (area of shape) with the proportion of all patients in annual cost band (dots) Around 3% of patients are responsible for nearly half the total patient costs © Nuffield Trust
  • 4. Predicting admissions in advance Change in average number of emergency bed days Predictive models try to identify people here © Nuffield Trust
  • 5. Health and social care event timeline © Nuffield Trust
  • 6. Patterns in routine data to identify high-risk people next year © Nuffield Trust
  • 7. Distribution of Combined Model risk scores Importance of risk adjustment Very high risk Top 0.5% Top 10% High risk Moderate risk 0.5% - 5% Low risk 5% - 20% 10% - 45% 20% - 100% 45% - 85% 85% - 100% General population WSD participants – receiving telehealth or telecare © Nuffield Trust
  • 8. Applications of predictive risk • Case finding for people at high risk of admission seen as increasingly important for people with LTCs and complex conditions • Evaluation and risk adjustment eg WSD • Predicting future costs eg work on resource allocation Related: Scope to make the most of linked data sets in describing care pathways © Nuffield Trust
  • 9. Choosing the predictive model bit • What event should we be aiming to predict? • What models and tools are available? • What data do I need and how often? • How often do predictive models need to be run? • How accurate is the model? • How much does it cost? © Nuffield Trust
  • 10. (1) Predictive tool = Predictive model + Software platform Inputs Processing Inpatient data Outpatient Tools to Predictive organise model GP data input data Population data Presentation and Outputs Patient lists with risk analysis tools score -Gaps in care -Priority lists Users © Nuffield Trust
  • 11. Age distribution and mean risk scores within a diagnostic categories © Nuffield Trust
  • 12. Testing for gaps in care © Nuffield Trust
  • 13. (2) Key metrics for performance of a model (PPV and sensitivity) 100% Positive predictive value 90% When the model says high risk how often 80% is it right? Sensitivity (Brown) 70% PPV (blue), 60% 50% 40% Sensitivity 30% What proportion of all 20% events will the model detect? 10% 0% 0 10 20 30 40 50 60 70 80 90 100 Threshold value (lower bound of defined 'high risk' group) Pooled 4-site 1k model © Nuffield Trust
  • 14. Typical performance of models – predicting events next year Predicting ... How many What proportion of all positives are events are found correct (PPV) (Sensitivity) Readmission based on prior 50%-75% 30-50% admissions eg PARR Admission to hospital from a 20-50% 5%-15% general population As above but just for highest 70-80% 5-10% risk groups (top 10%) Changes in social care use 20-50% 5-15% © Nuffield Trust
  • 15. (3) Emerging market in England • August 2011, the Department of Health announced that it had no plans to commission national updates of the latest Patients at Risk of Re-hospitalisation tool (PARR++) or the Combined Predictive Model • Range of new/established commercial organisation developing risk tools • Creation of new commissioning groups and new markets • Increasing ease of accessing GP data • Continuing financial pressures and the search for ways to reduce emergency hospital care. © Nuffield Trust
  • 16. Examples of case finding models available (with or without software platforms) SPARRA PARR (++) SPARRA MD Combined Predictive Model PRISM PEONY AHI Risk adjuster LACE ACGs (Johns Hopkins) MARA (Milliman Advanced Risk Adjuster) DxCGs (Verisk) Dr Foster Intelligence SPOKE (Sussex CPM) QResearch models eg QD score LACE RISC Variants on basic admission/readmission predictions: Short term readmissions Social care Condition specific tools Costs © Nuffield Trust
  • 17. (4) The model by itself doesn't change anything... Choosing an application • Which people should I target? • What interventions should we use? • Who will use it and how? What clinical staff need to see results? • Will some patients benefit more than others? • When can I expect to see a return on investment? © Nuffield Trust
  • 18. Summary • Predictive modelling is a practical case finding tool for identifying high risk patients • Growing market for predictive models – extending beyond simple annual predictions of readmissions • Ability to look at linked data valuable for other analyses • Technical details of model performance is important – but so how is the way the model is implemented • We hope today's conference will help you learn more about peoples’ experience of using these models. © Nuffield Trust
  • 19. The day ahead • A review around the UK • Examples of different ways that risk models have been applied in the NHS • A view from outside the UK Germany and US. • Developments in modelling • Open session...share your experiences. © Nuffield Trust
  • 20. www.nuffieldtrust.org.uk Sign-up for our newsletter www.nuffieldtrust.org.uk/newsletter/login.aspx Follow us on Twitter (http://twitter.com/NuffieldTrust) © Nuffield Trust © Nuffield Trust