The document discusses Mode Deactivation Therapy (MDT), an evidence-based treatment for adolescents. It provides details on the theoretical constructs of MDT, including that MDT views psychopathology as arising from "modes", which are networks of cognitive, affective, motivational and behavioral components that are activated in response to specific problems or demands. MDT aims to deactivate maladaptive modes by balancing perceptions, physiological responses, and behaviors in therapy sessions. The document also provides data on populations that have been treated with MDT and compares MDT to other therapies.