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Medication Administration Errors Associated with
Transitions of Care in Inpatients Receiving Dialysis in the
   Setting of Partial Implementation of an Electronic
   Medical Record and Computerized Physician Order
                           Entry

              Erik Venos, IrfanDhalla, Catherine Yu
         Department of Medicine, St. Michael’s Hospital, Toronto, ON
CONTEXT                                                    Her usual insulin regimen, a morning meal                STAKEHOLDER IDENTIFICATION AND
                                                            insulin injection and a basal insulin                   ENGAGEMENT
Patient transfers between and within                        injection, was reinitiated
 facilities are associated with negative                   She was transferred to the dialysis unit at                   Nephrology                     GIM
 patient outcomes, with the administration                  0730 for her regular dialysis                                                       GIM staff
 of insulin being a problematic area                       Her blood sugar was normal at 0800, 17.8                   Dialysis MD
                                                                                                                                                GIM resident
This project aimed to identify issues with                  mMat 1200 and 27 mM at 1500, requiring                    Dialysis fellow
                                                                                                                                                Endocrinology staff
 transitions within the hospital on these                   10 units of supplemental insulin for                      Renal pharmacist
                                                                                                                                                GIM pharmacist
 outcomes                                                                                                             Dialysis RNs
                                                            correction                                                                          GIM RNs
                                                           The eMAR did not report that the morning
SETTING                                                     meal insulin or basal insulin was                                   Face-to-face and by email
                                                            administered
General internal medicine (GIM) ward and a                                                                          CREATION OF PROCESS FLOW MAPS
 nephrology ward of a tertiary care centre,                INTERVENTION
 which operated a dialysis unit, serving out-                                                                       1. Physician ordering to nurse
 and inpatients                                            Identifying processes that led to this error                administration for patients admitted to
                                                                                                                       the GIM ward (figure 2)
Used computerized physician order entry
 (CPOE) along with an electronic medication                                                                         2. Patients admitted to GIM ward requiring
                                                           Four steps were undertaken:                                 dialysis, focusing on how insulin was
 administration record (eMAR), both being                                                                              given on dialysis days (figure 3)
 recently implemented on inpatient units in
                                                                                                                    3. Patients admitted to nephrology ward
 the hospital                                                  Identification of the relevant stakeholders             requiring dialysis, focusing on how
                                                                                                                       insulinwas given on dialysis days (figure
PROBLEM/ISSUE                                                                                                          4)
                                                                Engagement of the relevant stakeholders

Focusedon the medication administrations                                                                            MEASUREMENT AND ANALYSIS
                                                               Description and analysis patient transfers
  and transitions of care between a GIM                                  using a process flow map
  ward and a dialysis unit for a patient with                                                                       Identified a more complex system for Map 1
  type 1 diabetes and end stage renal                                                                                  compared to Map 2 (Figures 2 and 3)
  disease admitted to hospital                                 Utilizing this engagement and description            Found issues with insulin administration
                                                                      to attempt to improve the process


                       What medications are given before                                         Where does the patient eat?
                       the patient leaves the unit?                                              Does the dialysis RN give insulin routinely?
                       What medications are deferred?                                            Will administered medications be charted
Inpatient                                                            Patient in dialysis                                                              Inpatient returns
                       What handover between RNs                                                 on theeMAR or apaper chart?
leaving ward for                                                     unit for 4 hours                                                                 to home ward
                       occurs?
dialysis
         Figure 1: Considerations for designing a process flow map for hospitalized patients when leaving from and returning to their home unit from dialysis
Patient, receiving                          Medications are entered into                   Pharmacist acknowledges               Medications are sent to floor
dialysis, is admitted to                    CPOE by physician                              order and approves                    where RN receives them
hospital                                                                                   medication




                                                                                                                                 RN (via barcode) confirms that
                                                                                Patient receives medication from RN as
                           RN acknowledges patient receipt of                                                                    the patient’s medications
                                                                                ordered (insulin is drawn up in syringe
                           medication in electronic record                                                                       belong to patient
                                                                                from floor supply vial)


                                Figure 2: A process-flow map of medication administration for patients on a GIM ward

  Patient, receiving
                                              Medications are entered into                   Pharmacist acknowledges              Medications are sent to floor
  dialysis, is admitted to
                                              CPOE by physician                              order and approves                   where RN receives them
  hospital
                                                                                             medication

                                                                                                                                  Floor RN gives patient
                                       Sliding scale insulin                                                                      medications pre-dialysis and
                                                                       Dialysis RN notes insulin
                                       administered or                                                                            charts this oneMAR
                                                                       correction factor. Does
                                       physician called about          not give standard
                                       concern (medication             insulin (assumes given
  Floor RN notes                       administration noted on                                                                    Floor RN holds medication
                                                                       on home unit?)                                             scheduled during dialysis to be
  medications given in                 paper MAR)
  dialysis unit                                                                                                                   given after dialysis

  Floor RN gives scheduled                                             Performs capillary             Insulin
  medications post-dialysis                                            blood glucose and                                          Floor RN should print medi-
                                       Pt transported to GIM
                                                                       assesses whether                                           cation list and eMAR prior to
  RN to enter medications              ward from dialysis
                                                                       patient will eating.                                       patient leaving ward
  into eMARgiven in
                                                                       Meal is eaten in dialysis
  dialysis and after dialysis
                                                                                                            Dialysis RN should
  No specific protocol                                                                                      review patient’s      Patient goes off ward for
  existed as how insulin                                               Dialysis RN looks at                 medications from      dialysis
  was noted                                                            patient medication list              paper list
                                       Medication given or
                                                                       and dialysis medication
                                       physician called about
                                                                       list to determine IV
                                       concern
                                                                       meds and antibiotics to
                                                                       give during dialysis            Other medications

                Figure 3: A process flow map of medication administration for patients on a GIM ward receiving dialysis, on a dialysis
Insulin   Dialysis RN performs                                                                 Floor RN notes medica-
                                                                        Dialysis RN administers
                                           capillary blood glucose                                                              tions given in dialysis unit
                                                                        mealtime and basal insulins
                                           and assess whether
Patient leaves ward for                                                 provided by floor RN                                    Floor RN gives scheduled
                                           eating
dialysis. Scheduled insulin is                                                                                                  medications post-dialysis
                                                                                                         Patient returns to
drawn up from floor stock                                                                                                       RN to enter medications
                                           Dialysis RN looks at                                          nephrology ward
by floor RN and goes with                                                                                                       into eMARgiven in
the patient to dialysis unit               patient medication list      Dialysis RN gives mealtime                              dialysis and after dialysis
                                           and dialysismedication       medications provided by
                                           list to determine IV         floor RN                                                Insulin charted as
                                           meds and antibiotics to                                                              received in dialysis unit
                Other medications
                                           give during dialysis

                     Figure 4: A process flow map for patients admitted to a nephrology ward receiving dialysis, on a dialysis day

Maps were distributed among the relevant                 5. Basal insulins were not routinely stocked      3. The admission of patients with non-
 stakeholders for feedback and information                  in the dialysis unit                              dialysis related chief complaints to the
 provision                                                                                                    nephrology ward
                                                         The practices on the nephrology ward (on          4. Flagging the charts or medical record of
GAPS IN CARE                                               the same floor as the dialysis unit)               all patients with type 1 diabetes
                                                           revealed an interesting workaround to the
                                                           system (figure 4)                               LESSONS LEARNED
1. The dialysis unit is an outpatient facility           Floor RNs prepared CPOE-ordered insulin in
   using paper medication orders and a                     syringes, administered in dialysis when the
   paper MAR while the inpatient units use                                                                 1. The transition of care of patients
                                                           patient could be observed to be eating             between units, especially the dialysis
   CPOE and an electronic MAR;
   outpatients supply and administer their                                                                    unit, can lead to medication errors,
                                                         CONTRIBUTION TO PATIENT SAFETY AND                   particularly regarding insulin
   own insulin and other medications                     QUALITY IMPROVEMENT                                  administration
2. Patients were transferred between                                                                       2. CPOE and eMAR systems can have
   unitswith no specific protocol for nursing            Basal insulin to be supplied in the dialysis         drawbacks that need to be noted during
   handover                                                unit, so that insulin did not have to come         and after implementation
3. The patient was transferred between                     from the home ward if it was not supplied       3. The engagement of relevant stakeholders
   units at 0730, a time when nursing                      by the home ward                                   is an important strategy to gain
   handover occurs                                       Other measures were proposed for                     information about systems of care
                                                           consideration to improve patient safety:        4. The development of process flow maps
4. Patients were off the ward in
   hemodialysis, not briefly, but for four or            1. Development of the same workaround,               are helpful tools to understand complex
   more hours, making the routine non-                       as on the nephrology ward, for other             processes in the hospital
   administration of medication until the                    units                                         5. Understanding these processes can lead
   patient returns to the unit problematic               2. Providing dialysis RNs training on CPOE           to problem identification and the
                                                             and eMAR                                         creation of workable solutions

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Medication administration errors associated with transitions of care in inpatients receiving dialysis in the setting of partial implementation of an electronic medical record

  • 1. Medication Administration Errors Associated with Transitions of Care in Inpatients Receiving Dialysis in the Setting of Partial Implementation of an Electronic Medical Record and Computerized Physician Order Entry Erik Venos, IrfanDhalla, Catherine Yu Department of Medicine, St. Michael’s Hospital, Toronto, ON
  • 2. CONTEXT Her usual insulin regimen, a morning meal STAKEHOLDER IDENTIFICATION AND insulin injection and a basal insulin ENGAGEMENT Patient transfers between and within injection, was reinitiated facilities are associated with negative She was transferred to the dialysis unit at Nephrology GIM patient outcomes, with the administration 0730 for her regular dialysis GIM staff of insulin being a problematic area Her blood sugar was normal at 0800, 17.8 Dialysis MD GIM resident This project aimed to identify issues with mMat 1200 and 27 mM at 1500, requiring Dialysis fellow Endocrinology staff transitions within the hospital on these 10 units of supplemental insulin for Renal pharmacist GIM pharmacist outcomes Dialysis RNs correction GIM RNs The eMAR did not report that the morning SETTING meal insulin or basal insulin was Face-to-face and by email administered General internal medicine (GIM) ward and a CREATION OF PROCESS FLOW MAPS nephrology ward of a tertiary care centre, INTERVENTION which operated a dialysis unit, serving out- 1. Physician ordering to nurse and inpatients Identifying processes that led to this error administration for patients admitted to the GIM ward (figure 2) Used computerized physician order entry (CPOE) along with an electronic medication 2. Patients admitted to GIM ward requiring Four steps were undertaken: dialysis, focusing on how insulin was administration record (eMAR), both being given on dialysis days (figure 3) recently implemented on inpatient units in 3. Patients admitted to nephrology ward the hospital Identification of the relevant stakeholders requiring dialysis, focusing on how insulinwas given on dialysis days (figure PROBLEM/ISSUE 4) Engagement of the relevant stakeholders Focusedon the medication administrations MEASUREMENT AND ANALYSIS Description and analysis patient transfers and transitions of care between a GIM using a process flow map ward and a dialysis unit for a patient with Identified a more complex system for Map 1 type 1 diabetes and end stage renal compared to Map 2 (Figures 2 and 3) disease admitted to hospital Utilizing this engagement and description Found issues with insulin administration to attempt to improve the process What medications are given before Where does the patient eat? the patient leaves the unit? Does the dialysis RN give insulin routinely? What medications are deferred? Will administered medications be charted Inpatient Patient in dialysis Inpatient returns What handover between RNs on theeMAR or apaper chart? leaving ward for unit for 4 hours to home ward occurs? dialysis Figure 1: Considerations for designing a process flow map for hospitalized patients when leaving from and returning to their home unit from dialysis
  • 3. Patient, receiving Medications are entered into Pharmacist acknowledges Medications are sent to floor dialysis, is admitted to CPOE by physician order and approves where RN receives them hospital medication RN (via barcode) confirms that Patient receives medication from RN as RN acknowledges patient receipt of the patient’s medications ordered (insulin is drawn up in syringe medication in electronic record belong to patient from floor supply vial) Figure 2: A process-flow map of medication administration for patients on a GIM ward Patient, receiving Medications are entered into Pharmacist acknowledges Medications are sent to floor dialysis, is admitted to CPOE by physician order and approves where RN receives them hospital medication Floor RN gives patient Sliding scale insulin medications pre-dialysis and Dialysis RN notes insulin administered or charts this oneMAR correction factor. Does physician called about not give standard concern (medication insulin (assumes given Floor RN notes administration noted on Floor RN holds medication on home unit?) scheduled during dialysis to be medications given in paper MAR) dialysis unit given after dialysis Floor RN gives scheduled Performs capillary Insulin medications post-dialysis blood glucose and Floor RN should print medi- Pt transported to GIM assesses whether cation list and eMAR prior to RN to enter medications ward from dialysis patient will eating. patient leaving ward into eMARgiven in Meal is eaten in dialysis dialysis and after dialysis Dialysis RN should No specific protocol review patient’s Patient goes off ward for existed as how insulin Dialysis RN looks at medications from dialysis was noted patient medication list paper list Medication given or and dialysis medication physician called about list to determine IV concern meds and antibiotics to give during dialysis Other medications Figure 3: A process flow map of medication administration for patients on a GIM ward receiving dialysis, on a dialysis
  • 4. Insulin Dialysis RN performs Floor RN notes medica- Dialysis RN administers capillary blood glucose tions given in dialysis unit mealtime and basal insulins and assess whether Patient leaves ward for provided by floor RN Floor RN gives scheduled eating dialysis. Scheduled insulin is medications post-dialysis Patient returns to drawn up from floor stock RN to enter medications Dialysis RN looks at nephrology ward by floor RN and goes with into eMARgiven in the patient to dialysis unit patient medication list Dialysis RN gives mealtime dialysis and after dialysis and dialysismedication medications provided by list to determine IV floor RN Insulin charted as meds and antibiotics to received in dialysis unit Other medications give during dialysis Figure 4: A process flow map for patients admitted to a nephrology ward receiving dialysis, on a dialysis day Maps were distributed among the relevant 5. Basal insulins were not routinely stocked 3. The admission of patients with non- stakeholders for feedback and information in the dialysis unit dialysis related chief complaints to the provision nephrology ward The practices on the nephrology ward (on 4. Flagging the charts or medical record of GAPS IN CARE the same floor as the dialysis unit) all patients with type 1 diabetes revealed an interesting workaround to the system (figure 4) LESSONS LEARNED 1. The dialysis unit is an outpatient facility Floor RNs prepared CPOE-ordered insulin in using paper medication orders and a syringes, administered in dialysis when the paper MAR while the inpatient units use 1. The transition of care of patients patient could be observed to be eating between units, especially the dialysis CPOE and an electronic MAR; outpatients supply and administer their unit, can lead to medication errors, CONTRIBUTION TO PATIENT SAFETY AND particularly regarding insulin own insulin and other medications QUALITY IMPROVEMENT administration 2. Patients were transferred between 2. CPOE and eMAR systems can have unitswith no specific protocol for nursing Basal insulin to be supplied in the dialysis drawbacks that need to be noted during handover unit, so that insulin did not have to come and after implementation 3. The patient was transferred between from the home ward if it was not supplied 3. The engagement of relevant stakeholders units at 0730, a time when nursing by the home ward is an important strategy to gain handover occurs Other measures were proposed for information about systems of care consideration to improve patient safety: 4. The development of process flow maps 4. Patients were off the ward in hemodialysis, not briefly, but for four or 1. Development of the same workaround, are helpful tools to understand complex more hours, making the routine non- as on the nephrology ward, for other processes in the hospital administration of medication until the units 5. Understanding these processes can lead patient returns to the unit problematic 2. Providing dialysis RNs training on CPOE to problem identification and the and eMAR creation of workable solutions