Monkeypox
Download as PPTX, PDF3 likes12,691 views
Monkeypox is caused by an enveloped double-stranded DNA virus in the orthopoxvirus genus of the Poxviridae family. It can spread through direct contact with infectious rash, scabs, or body fluids, respiratory secretions during prolonged face-to-face contact, or touching items that previously touched the infectious rash or body fluids. The incubation period is usually 6 to 13 days. Diagnosis involves polymerase chain reaction testing, while treatment includes the antiviral tecovirimat and vaccines for smallpox may provide limited protection as both diseases are from the same family.
Monkeypox
- 1. Monkeypox
- 3. The pathogen 1. Enveloped double-stranded DNA virus 2. Orthopoxvirus genus 3. Poxviridae family.
- 4. Transmission 1. Direct contact with the infectious rash, scabs, or body fluids, 2. Respiratory secretions during prolonged face-to-face contact,
- 5. 3. Touching items that previously touched the infectious rash or body fluids, 3. Pregnant people can spread the virus to their foetus through the placenta
- 6. Signs and symptoms The incubation period of monkeypox is usually from 6 to 13 days but can range from 5 to 21 days.
- 8. Diagnosis • Lymphadenopathy can be a clinical feature to distinguish monkeypox from chickenpox or smallpox. • Polymerase chain reaction (PCR) is the preferred laboratory test given its accuracy and sensitivity. • As orthopoxviruses are serologically cross-reactive, antigen and antibody detection methods do not provide monkeypox-specific confirmation.
- 9. Therapeutics • An antiviral developed to treat smallpox tecovirimat, commercialized as TPOXX has been approved for treatment of monkeypox. • Other vaccines for smallpox may provide limited protection since both diseases are from the same family. • Immune globulin may be recommended for severe cases.
- 10. THANK YOU