Programmatic video advertising spending has grown exponentially, hitting $6 billion in 2014 and estimated to reach $7.7 billion in 2015. Most trading will eventually be handled through programmatic channels as it expands advertiser reach and provides market intelligence. When starting with programmatic video, companies should establish a strategy, create buyer relationships, and leverage it as a research tool while being flexible. Programmatic addresses challenges of direct sales and provides options for private deals versus open marketplaces. Publishers face technical challenges around ad calling that require consideration.