The document provides advice from over 50 CEOs for new CEOs taking on their first CEO role. The key pieces of advice are to: 1) Move quickly to establish a narrow set of high-impact priorities and drive them relentlessly with a sense of urgency in the first 6-9 months. 2) Make fast decisions around talent, even if difficult, and remove underperforming people from key roles. 3) Stop doing your old job and establish a new identity as the leader, delegating tasks even if you think you can do them better. 4) Admit your weaknesses and seek help from other talented leaders to complement your skills and focus on areas of maximum impact.