New horizons in cardiovascular magnetic resonance imaging
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This document discusses advancements in magnetic resonance imaging (MRI) techniques for cardiovascular diseases, highlighting new pulse sequences and applications in cardiac and vascular imaging. It categorizes contributions into cardiac imaging applications, advanced vascular MRI techniques, and preclinical hemodynamics visualization. The compilation serves as a snapshot of current research efforts and innovations in the field of cardiovascular MRI.
New horizons in cardiovascular magnetic resonance imaging
- 1. © Cardiovascular Diagnosis and Therapy. All rights reserved. Cardiovasc Diagn Ther 2014;4(2):54-55www.thecdt.org This issue of ‘Cardiovascular Diagnosis and Therapy (CDT)’ has a special focus on application and development of magnetic resonance imaging (MRI) in cardiovascular diseases. The challenges associated with imaging of the heart and the huge disease burden associated with cardiovascular diseases has been one of the major motivations in the last few years for the development of new MRI techniques. A realm of new pulse sequences, either focusing on ‘freezing’ motion or on providing improved endogenous contrast mechanisms were developed in this context and are now being evaluated in clinical and preclinical research efforts focusing on the heart and vascular circulation. The contributions in this focus fall into three categories. The first category describes application directly related to cardiac imaging, while the second category describes advanced MRI techniques for vascular phenomena, in particular the clinical manifestations of generalized artherosclerosis. Articles of the third category introduce preclinical techniques for visualizing and quantifying hemodynamics and how these techniques can be integrated in the MRI workflow. For the first category, an expert overview of these new MRI technologies is provided in the review article of Krishnamurthy et al. while Jellis et al. and Kohan et al. focus on specific topics, i.e., advances in T1 mapping and Takosubo cardiomyopathy, respectively. Examples of the applications of these new techniques are provided by Tavakoli et al., who demonstrate how tagging, a cardiac MRI technique, can be utilized to assess subendocardial versus subepicardial left ventricular twist; by Karmonik et al., who present a technology for the fast in vivo quantification of T1 and T2 relaxation times with an inversion steady state free precession technique and by De Stefano et al. correlating the rate of cardiovascular events with acute myocarditis. For the second category, Gordon et al. provide an introduction into the dynamic contrast-enhanced MRI technique. Another MR microperfusion technique, namely blood-oxygen level dependent MRI is discussed in the setting of peripheral arterial occlusive disease by Aschwanden et al. Presenting advanced technologies for vascular applications, Müller-Eschner et al. demonstrate a new post-processing technique based on segmentation methods for quantifying 3D vessel morphometry. For the third category, Stankovic et al., give an overview of the technique of 4D flow imaging using MRI and Wentland et al. address the usefulness of pulse wave velocity as a potential biomarker for aortic stiffness. Rengier et al. then focus on 4D flow imaging and illustrate its application for non-invasively mapping of pressure differences for aortic coarctations. Karmonik et al. demonstrate how MRI velocity measurements can be used to validate results from computational fluid dynamics simulations in cerebral aneurysms. Furthermore Ohana et al. use computed tomographic angiography for stenosis measurements in the superficial femoral artery and discuss how the approach can be transferred to magnetic resonance angiography. Of course, the collection of articles presented here in this focus issue can only be considered as a very small snapshot of all excellent efforts currently undertaken in the field of cardiovascular MRI. However, due to their broad coverage of a large variety of MR techniques from cardiac over vascular applications of MRI and their correlations and associations with ultrasound, computed tomographic angiography and computational simulations from leading international clinical research groups, the reader of this special issue is provided with an exciting selection on the evolving topic of cardiovascular MRI. Sasan Partovi & Christof Karmonik Preface New horizons in cardiovascular magnetic resonance imaging
- 2. 55Cardiovascular Diagnosis and Therapy, Vol 4, No 2 April 2014 © Cardiovascular Diagnosis and Therapy. All rights reserved. Cardiovasc Diagn Ther 2014;4(2):54-55www.thecdt.org Sasan Partovi, MD. University Hospitals Case Medical Center, Department of Radiology, Case Western Reserve University, Cleveland, Ohio, USA. (Email: sxp509@case.edu.) Christof Karmonik, PhD. Houston Methodist Hospital, Department of Neurosurgery, Weill Cornell Medical College, Houston, Texas, USA. (Email: CKarmonik@houstonmethodist.org.) Cite this article as: Partovi S, Karmonik C. New horizons in cardiovascular magnetic resonance imaging. Cardiovasc Diagn Ther 2014;4(2):54-55. doi: 10.3978/j.issn.2223-3652.2014.03.05 doi: 10.3978/j.issn.2223-3652.2014.03.05 Disclosure: The authors declare no conflict of interest. View this article at: http://www.thecdt.org/article/view/3637/4512