The document discusses and compares the Agency for Healthcare Research and Quality (AHRQ) and the Patient-Centered Outcomes Research Institute (PCORI). AHRQ focuses on researching how the overall healthcare system impacts issues like quality, spending, and disparities. PCORI focuses on funding comparative effectiveness research from a patient perspective on specific diseases and developing research methods. While both aim to reduce costs, AHRQ may benefit insurance companies more than patients, and PCORI research may not always be implemented by healthcare organizations.