Nervous System Edison D. Ramos, RMT, MPH Assistant Professor II College of Medical Technology Manila Central University
INTRODUCTION The nervous system is the body’s control center and communication network. It directs the functions of body’s organs and systems. It allows us to interpret what is occurring in our external environment and helps us to decide how to react to any environmental changes. It shares in the maintenance of homeostasis with endocrine system.
Spinal Cord and Spinal Nerve Structure Functions Have specific perform specific Enables includes include Neurons Transmission and interpretation of sensation, reaction to stimuli Allow Neuroglia Protection and support of neurons Allow Meninges Allow Protection and nourishment of neural tissue in brain and spinal cord Spinal cord and spinal nerves Allow Sending sensory impulses to brain, integrating reflexes and sending motor impulses to muscles
ORGANIZATION 2 Major Categories of Nervous System 1. CENTRAL NERVOUS SYSTEM (CNS) - control center for the whole system - consists of brain and spinal cord 2. PERIPHERAL NERVOUS SYSTEM (PNS) - consists of all nerves that connect the brain and spinal cord with  sensory receptors, muscles and glands. a.  Afferent Peripheral System - consist of sensory neurons that convey information from   receptors in the periphery of the body to the brain and   spinal cord
b.  Efferent Peripheral System - consists of motor neurons that convey information from   the brain and spinal cord to muscles and glands. b.1.  Somatic Nervous System  – conducts impulses from the brain and spinal cord to skeletal muscle thereby causing us to react to changes in environment b.2.  Autonomic Nervous System  – conducts impulses from the brain and spinal cord to smooth and cardiac muscle tissue b.2.1. Sympathetic Division - stimulate or speeds up activity and thus   involves energy expenditures. - uses norepinephrine b.2.2. Parasympathetic Division - stimulates or speeds up the body’s vegetative   activities such as digestion, urination,   defecation and slows down other activities - uses acetylcholine
CLASSIFICATION OF NERVE CELLS Neurons are nerve cells that transmit nerve impulses in the form of electrochemical changes. Neuroglial cells are nerve cells that support and protect neuron. Types of Neuroglia TYPES DESCRIPTION Astrocytes Star-shaped cells that function in the blood-brain barrier to prevent toxic substances from entering the brain Oligodendroglia Provide support and connection Microglia Involved in the phagocytosis of unwanted substances Epedymal cells Form the lining of the cavities in the brain and spinal cord Schwann cells Located only in the PNS and make up the neurilemma and myelin sheath. (also called as NEUROLEMMOCYTES)
STRUCTURE OF NEURON
DENDRITES – extension of the cell body and are the receptive areas of the neuron. AXON – single long extension of the cell body that begins as a slight enlargement. The axon may branch but at its end there are many extension called AXON TERMINAL On large peripheral axons, a SCHWANN CELL produces a fatty MYELIN SHEATH that surrounds and insulates the axon. Narrow gaps in the sheath are called NODES OF RANVIER (also called as Neurofibral Nodes)
 
STRUCTURAL CLASSIFICATION OF NEURONS 1.  Multipolar Neuron - have several dendrites coming off the cell body and one axon. Most neurons in the brain and spinal cord  are multipolar. 2.  Bipolar Neuron - have one dendrite and one axon. They are found in the retina of the eye, inner ear and the olfactory area of the nose. 3.  Unipolar Neuron - have only one process extending from the cell body, which then branches  into a central branch that functions as an axon and a peripheral branch functions as dendrite . Most sensory neurons are Unipolar.
 
FUNCTIONAL CLASSIFICATION OF NEURONS RECEPTORS detect stimuli in our environment. SENSORY or AFFERENT NEURONS receive the impulse directly from the receptor site. INTERNUNCIAL or ASSOCIATION NEURON found in the brain and spinal cord, they transmit the impulse for interpretation and processing. MOTOR or EFFERENT NEURONS bring about the reaction to the stimulus
SYNAPSE – area where the terminal branches of an axon are close to but not touching the dendrites of another neuron. - When impulse reaches the axon , it triggers the release of a neurotransmitter into synaptic cleft which allows impulse to travel across the synapse. Neurotransmitter: Acetylcholine Epinephrine Norepinephrine Dopamine  Endorphins
REFLEX ARC Is an involuntary reaction to an external stimulus. 5 Components of Reflex Arc Sensory receptor in the skin Sensory or afferent neuron Association of internuncial neurons in the spinal cord Motor or efferent neuron Effector organ
SPINAL CORD continuation of the medulla oblongata made up of 31 segments, each give rise to a pair of spinal nerves it is protected by SPINAL MENINGES the outermost spinal meninx is the  dura mater  or  tough mother , the middle spinal meninx is the  spider layer  or  arachnoid mater  and the innermost meninx is the  pia mater  or  delicate mother . Between the dura mater and the arachnoid mater is a space called SUBDURAL SPACE which contains serous fluid. Between the arachnoid and pia mater is the SUBARACHNOID SPACE in which the CSF circulates.
 
BRAIN it is protected by the cranial bones, cranial meninges and CSF the brain is divided into four main parts: 1. BRAINSTEM – medulla oblongata, pons varolii, midbrain 2. DIENCEPHALON – thalamus, hypothalamus 3. CEREBRUM  4. CEREBELLUM
BRAIN Have specific perform specific Structure Functions Enables Brain Cranial meninges Protects Brainstem Diencephalon Cerebrum Cerebellum Consciousness, heartbeat, breathing, visual, auditory Temperature and pain recognition, homeostasis, thirst center, sleep patterns Muscular movements, emotions, intelligence Coordination of muscular movements, balance CSF Include Shock absorption, circulation of nutrients
Brainstem
 
 
Areas of Brain Function
Autonomic Nervous System Have specific perform specific Structure Functions Sympathetic Parasympathetic Nose Tongue Eye Ear Increase of heartbeat and breathing rate, energy expenditure, cope with stress Restoration of body to non stress state, controls vegetative activities Sense of smell Sour, bitter, sour, salty Sense of sight Sense of hearing and balance
 
CRANIAL NERVES # NAME FUNCTIONS I Olfactory Sensory: Conveys impulses related to smell II Optic Sensory: Conveys impulses related to sight III Oculomotor Motor: Movement of the eyeball, regulation of the size of the pupil IV Trochlear Motor: Eye movements V Trigeminal Sensory: Sensations of head and face Motor: Mastication Note: Divided into 3 branches – ophthalmic branch, maxillary branch and mandibular branch VI Abducens Motor: Movement of the eyeball VII Facial Sensory: Taste Motor: Facial expression, secretion of saliva VIII Vestibulocochlear Sensory: Balance, hearing Note: Divided into 2 branches – vestibular branch responsible for balance and cochlear branch responsible for hearing
IX Glossopharyngeal Sensory: Taste Motor: Swallowing, secretion of saliva X Vagus Sensory: Sensation of organs supplied Motor: Movement of organs supplied Note: Supplies the head, pharynx, bronchus, esophagus, liver and stomach XI Accessory Motor: Shoulder movement, turning of head, voice production XII Hypoglossal Motor: Tongue movements
 
DISORDERS OF THE NERVOUS SYSTEM ALZHEIMER’S DISEASE - results in severe mental retardation, it usually affect older people but may begin in middle life with symptoms of memory loss and behavioral changes. The disease produces a loss of neurons resulting decrease brain size. CEREBROVASCULAR ACCIDENT (stroke) - caused by a clot or thrombus in a blood vessel. This situation can result in localized cell death due to lack of blood supply in the tissue. MENINGITIS - inflammation of the meninges due to bacterial or viral infections. Severe cases may result in paralysis, coma and death
ENCEPHALITIS - inflammation of the brain tissue usually caused by a virus transmitted by the bite of a mosquito TETANUS - caused by the introduction of bacterium Clostridium tetani into an open wound. The bacteria produces neurotoxin that affects motor neuron in the spinal cord and brainstem PARKINSON’S DISEASE - characterized by tremors of the hand when resting and a slow shuffling walk with rigidity of muscular movements
CEREBRAL PALSY - condition caused by brain damage during brain development or the birth process. EPILEPSY - caused by a disorder in the brain where certain parts of it are overactive producing convulsive seizures and possible loss of consciousness. HEADACHE (cephalalgia) - can be caused by a variety of factors, from muscle tension and anxiety to swollen sinuses and toothache, can also be caused by inflammation of the meninges, brain tumors and vascular changes in the blood supply to the brain.
END

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Nervous system

  • 1. Nervous System Edison D. Ramos, RMT, MPH Assistant Professor II College of Medical Technology Manila Central University
  • 2. INTRODUCTION The nervous system is the body’s control center and communication network. It directs the functions of body’s organs and systems. It allows us to interpret what is occurring in our external environment and helps us to decide how to react to any environmental changes. It shares in the maintenance of homeostasis with endocrine system.
  • 3. Spinal Cord and Spinal Nerve Structure Functions Have specific perform specific Enables includes include Neurons Transmission and interpretation of sensation, reaction to stimuli Allow Neuroglia Protection and support of neurons Allow Meninges Allow Protection and nourishment of neural tissue in brain and spinal cord Spinal cord and spinal nerves Allow Sending sensory impulses to brain, integrating reflexes and sending motor impulses to muscles
  • 4. ORGANIZATION 2 Major Categories of Nervous System 1. CENTRAL NERVOUS SYSTEM (CNS) - control center for the whole system - consists of brain and spinal cord 2. PERIPHERAL NERVOUS SYSTEM (PNS) - consists of all nerves that connect the brain and spinal cord with sensory receptors, muscles and glands. a. Afferent Peripheral System - consist of sensory neurons that convey information from receptors in the periphery of the body to the brain and spinal cord
  • 5. b. Efferent Peripheral System - consists of motor neurons that convey information from the brain and spinal cord to muscles and glands. b.1. Somatic Nervous System – conducts impulses from the brain and spinal cord to skeletal muscle thereby causing us to react to changes in environment b.2. Autonomic Nervous System – conducts impulses from the brain and spinal cord to smooth and cardiac muscle tissue b.2.1. Sympathetic Division - stimulate or speeds up activity and thus involves energy expenditures. - uses norepinephrine b.2.2. Parasympathetic Division - stimulates or speeds up the body’s vegetative activities such as digestion, urination, defecation and slows down other activities - uses acetylcholine
  • 6. CLASSIFICATION OF NERVE CELLS Neurons are nerve cells that transmit nerve impulses in the form of electrochemical changes. Neuroglial cells are nerve cells that support and protect neuron. Types of Neuroglia TYPES DESCRIPTION Astrocytes Star-shaped cells that function in the blood-brain barrier to prevent toxic substances from entering the brain Oligodendroglia Provide support and connection Microglia Involved in the phagocytosis of unwanted substances Epedymal cells Form the lining of the cavities in the brain and spinal cord Schwann cells Located only in the PNS and make up the neurilemma and myelin sheath. (also called as NEUROLEMMOCYTES)
  • 8. DENDRITES – extension of the cell body and are the receptive areas of the neuron. AXON – single long extension of the cell body that begins as a slight enlargement. The axon may branch but at its end there are many extension called AXON TERMINAL On large peripheral axons, a SCHWANN CELL produces a fatty MYELIN SHEATH that surrounds and insulates the axon. Narrow gaps in the sheath are called NODES OF RANVIER (also called as Neurofibral Nodes)
  • 9.  
  • 10. STRUCTURAL CLASSIFICATION OF NEURONS 1. Multipolar Neuron - have several dendrites coming off the cell body and one axon. Most neurons in the brain and spinal cord are multipolar. 2. Bipolar Neuron - have one dendrite and one axon. They are found in the retina of the eye, inner ear and the olfactory area of the nose. 3. Unipolar Neuron - have only one process extending from the cell body, which then branches into a central branch that functions as an axon and a peripheral branch functions as dendrite . Most sensory neurons are Unipolar.
  • 11.  
  • 12. FUNCTIONAL CLASSIFICATION OF NEURONS RECEPTORS detect stimuli in our environment. SENSORY or AFFERENT NEURONS receive the impulse directly from the receptor site. INTERNUNCIAL or ASSOCIATION NEURON found in the brain and spinal cord, they transmit the impulse for interpretation and processing. MOTOR or EFFERENT NEURONS bring about the reaction to the stimulus
  • 13. SYNAPSE – area where the terminal branches of an axon are close to but not touching the dendrites of another neuron. - When impulse reaches the axon , it triggers the release of a neurotransmitter into synaptic cleft which allows impulse to travel across the synapse. Neurotransmitter: Acetylcholine Epinephrine Norepinephrine Dopamine Endorphins
  • 14. REFLEX ARC Is an involuntary reaction to an external stimulus. 5 Components of Reflex Arc Sensory receptor in the skin Sensory or afferent neuron Association of internuncial neurons in the spinal cord Motor or efferent neuron Effector organ
  • 15. SPINAL CORD continuation of the medulla oblongata made up of 31 segments, each give rise to a pair of spinal nerves it is protected by SPINAL MENINGES the outermost spinal meninx is the dura mater or tough mother , the middle spinal meninx is the spider layer or arachnoid mater and the innermost meninx is the pia mater or delicate mother . Between the dura mater and the arachnoid mater is a space called SUBDURAL SPACE which contains serous fluid. Between the arachnoid and pia mater is the SUBARACHNOID SPACE in which the CSF circulates.
  • 16.  
  • 17. BRAIN it is protected by the cranial bones, cranial meninges and CSF the brain is divided into four main parts: 1. BRAINSTEM – medulla oblongata, pons varolii, midbrain 2. DIENCEPHALON – thalamus, hypothalamus 3. CEREBRUM 4. CEREBELLUM
  • 18. BRAIN Have specific perform specific Structure Functions Enables Brain Cranial meninges Protects Brainstem Diencephalon Cerebrum Cerebellum Consciousness, heartbeat, breathing, visual, auditory Temperature and pain recognition, homeostasis, thirst center, sleep patterns Muscular movements, emotions, intelligence Coordination of muscular movements, balance CSF Include Shock absorption, circulation of nutrients
  • 20.  
  • 21.  
  • 22. Areas of Brain Function
  • 23. Autonomic Nervous System Have specific perform specific Structure Functions Sympathetic Parasympathetic Nose Tongue Eye Ear Increase of heartbeat and breathing rate, energy expenditure, cope with stress Restoration of body to non stress state, controls vegetative activities Sense of smell Sour, bitter, sour, salty Sense of sight Sense of hearing and balance
  • 24.  
  • 25. CRANIAL NERVES # NAME FUNCTIONS I Olfactory Sensory: Conveys impulses related to smell II Optic Sensory: Conveys impulses related to sight III Oculomotor Motor: Movement of the eyeball, regulation of the size of the pupil IV Trochlear Motor: Eye movements V Trigeminal Sensory: Sensations of head and face Motor: Mastication Note: Divided into 3 branches – ophthalmic branch, maxillary branch and mandibular branch VI Abducens Motor: Movement of the eyeball VII Facial Sensory: Taste Motor: Facial expression, secretion of saliva VIII Vestibulocochlear Sensory: Balance, hearing Note: Divided into 2 branches – vestibular branch responsible for balance and cochlear branch responsible for hearing
  • 26. IX Glossopharyngeal Sensory: Taste Motor: Swallowing, secretion of saliva X Vagus Sensory: Sensation of organs supplied Motor: Movement of organs supplied Note: Supplies the head, pharynx, bronchus, esophagus, liver and stomach XI Accessory Motor: Shoulder movement, turning of head, voice production XII Hypoglossal Motor: Tongue movements
  • 27.  
  • 28. DISORDERS OF THE NERVOUS SYSTEM ALZHEIMER’S DISEASE - results in severe mental retardation, it usually affect older people but may begin in middle life with symptoms of memory loss and behavioral changes. The disease produces a loss of neurons resulting decrease brain size. CEREBROVASCULAR ACCIDENT (stroke) - caused by a clot or thrombus in a blood vessel. This situation can result in localized cell death due to lack of blood supply in the tissue. MENINGITIS - inflammation of the meninges due to bacterial or viral infections. Severe cases may result in paralysis, coma and death
  • 29. ENCEPHALITIS - inflammation of the brain tissue usually caused by a virus transmitted by the bite of a mosquito TETANUS - caused by the introduction of bacterium Clostridium tetani into an open wound. The bacteria produces neurotoxin that affects motor neuron in the spinal cord and brainstem PARKINSON’S DISEASE - characterized by tremors of the hand when resting and a slow shuffling walk with rigidity of muscular movements
  • 30. CEREBRAL PALSY - condition caused by brain damage during brain development or the birth process. EPILEPSY - caused by a disorder in the brain where certain parts of it are overactive producing convulsive seizures and possible loss of consciousness. HEADACHE (cephalalgia) - can be caused by a variety of factors, from muscle tension and anxiety to swollen sinuses and toothache, can also be caused by inflammation of the meninges, brain tumors and vascular changes in the blood supply to the brain.
  • 31. END