Newton's laws of motion describe the principles governing the movement of objects, including the concepts of inertia, force as mass times acceleration (F=ma), and action-reaction pairs. The first law states that an object remains at rest or in uniform motion unless acted upon by an unbalanced force, while the second law defines the relationship between force, mass, and acceleration. The third law states that for every action, there is an equal and opposite reaction, illustrating interactions in various physical scenarios.