Node.js is a platform for building scalable network applications using JavaScript. It uses an event-driven, non-blocking I/O model that makes it lightweight and efficient, especially for real-time web applications with many simultaneous connections. Node.js applications are written in JavaScript and can be run on Windows, Linux, and macOS. Common uses of Node.js include building web servers, real-time web applications, IoT applications, and microservices. Node.js applications are deployed to cloud platforms like Heroku, Nodejitsu, and Microsoft Azure.