Notes BariatricsGarth R Jacobsen, M.D.Surgical Program DirectorUCSD Center for the Future of SurgeryAssociate Residency Program DirectorUC San Diego Department of Surgery
Bias?Ethicon	Honoraria: Speaking, Consulting, 			Research Grants, Fellowship SupportW.L. Gore: 	Honoraria: Speaking, Consulting, 			Writing, Fellowship SupportUSGI: 	Honoraria: Speaking, Consulting, 			Research Grants, ProctoringCovidien 	Honorarium: SpeakingLifeCell: 	Honorarium: ConsultingDavol: 	Honoraria, Speaking, ConsultingMTF: 	Honorarium, WritingNovus: 	Honorarium; Consulting
WHY NOTES ?POTENTIAL  ADVANTAGES: Decreased risk of abdominal wall hernia
 Decreased pain
 Decreased risk of infection/seroma
 Better cosmesisMETHODS- 2 arms: 21 patientsTransvaginal sleeve gastrectomy with remnant    extraction: 3 patients Transoral remnant extraction (TORE): 18 patients                         14 women and 4 men
Patient Characteristics Mean age of patients: 49 years (range 29-63 yrs)Mean pre-operative BMI: 46.1 (range 33-60)
CO-MORBIDITIES* PSH significant for laparoscopic hysterectomy in 1 patient in the transvaginal series.
Standardized technique for trans-oral extraction (TORE)
Notes bariatrics 2
RESULTS- Average volume of stomach extracted:  470cc (20 X 5 X 2.5 cm)Average OR time:  Transvaginal series- 135 minutes                                TORE series- 91 minutes                                 (transoral extraction- 12 min)
POST- OPERATIVE COURSE Average hospitalization: 2 days
 Post-op complications: NONE
 No sexual dysfunction
 Follow-up ranges from 1 month -2.5 yearsWEIGHT LOSS NOTES cohort : 38 % at 6 months                             54% at 1 year Identical to our traditional laparoscopic  sleeve gastrectomy series
SUMMARY- Transvaginal sleeve gastrectomy is a safe approach- Transoral extraction of remnant stomach is feasible- Weight loss is not compromised when compared to conventional laparoscopic techniques
CONCLUSIONTransvaginal and Transoral Remnant Extraction (TORE) are viable options for sleeve gastrectomy This experience represents the first step towards a purely NOTES bariatric procedure

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Notes bariatrics 2

  • 1. Notes BariatricsGarth R Jacobsen, M.D.Surgical Program DirectorUCSD Center for the Future of SurgeryAssociate Residency Program DirectorUC San Diego Department of Surgery
  • 2. Bias?Ethicon Honoraria: Speaking, Consulting, Research Grants, Fellowship SupportW.L. Gore: Honoraria: Speaking, Consulting, Writing, Fellowship SupportUSGI: Honoraria: Speaking, Consulting, Research Grants, ProctoringCovidien Honorarium: SpeakingLifeCell: Honorarium: ConsultingDavol: Honoraria, Speaking, ConsultingMTF: Honorarium, WritingNovus: Honorarium; Consulting
  • 3. WHY NOTES ?POTENTIAL ADVANTAGES: Decreased risk of abdominal wall hernia
  • 5. Decreased risk of infection/seroma
  • 6. Better cosmesisMETHODS- 2 arms: 21 patientsTransvaginal sleeve gastrectomy with remnant extraction: 3 patients Transoral remnant extraction (TORE): 18 patients 14 women and 4 men
  • 7. Patient Characteristics Mean age of patients: 49 years (range 29-63 yrs)Mean pre-operative BMI: 46.1 (range 33-60)
  • 8. CO-MORBIDITIES* PSH significant for laparoscopic hysterectomy in 1 patient in the transvaginal series.
  • 9. Standardized technique for trans-oral extraction (TORE)
  • 11. RESULTS- Average volume of stomach extracted: 470cc (20 X 5 X 2.5 cm)Average OR time: Transvaginal series- 135 minutes TORE series- 91 minutes (transoral extraction- 12 min)
  • 12. POST- OPERATIVE COURSE Average hospitalization: 2 days
  • 14. No sexual dysfunction
  • 15. Follow-up ranges from 1 month -2.5 yearsWEIGHT LOSS NOTES cohort : 38 % at 6 months 54% at 1 year Identical to our traditional laparoscopic sleeve gastrectomy series
  • 16. SUMMARY- Transvaginal sleeve gastrectomy is a safe approach- Transoral extraction of remnant stomach is feasible- Weight loss is not compromised when compared to conventional laparoscopic techniques
  • 17. CONCLUSIONTransvaginal and Transoral Remnant Extraction (TORE) are viable options for sleeve gastrectomy This experience represents the first step towards a purely NOTES bariatric procedure
  • 18. Primary Endoscopic TherapyGoal to build on utilization of durable anchorsNotes Gastric ClosureROSETarget anatomic and physiologic effectsRestrictive? Suppression of AppetiteTarget Obesity epidemic with a low risk procedure
  • 20. PotentialFeasibility Pilot completed with encouraging resultsRevision of TechnologyFirst generation G-prox to small for commercial viabilityFollow up with a prospective trial in patients with BMI between 28 and 35Currently recruiting
  • 21. ConclusionsThe first wide spread application of Natural Orifice Technology will be intralumenalThe platform offers a durable intralumenal anchorPrimary procedures may offer a solution to the obesity epidemic with minimal patient risk