2. INTRODUCTION
Obsessive-compulsive disorder is a mental disorder whose main symptoms
include obsessions and compulsions, driving the person to engage in unwanted,
often-times distress behaviors or thoughts. The obsessions are usually related
to a sense of harm, risk or injury. The common Obsessions include concern
about contamination, doubt, fear of loss or letting go, fear of physically injuring
someone. It’s treatment is done through a combination of psychiatric
medications and psychotherapy.
Obsessive compulsive disorder(OCD) is an
anxiety disorder.
The person has recurring thoughts or
images(obsessions) and/or repetitive, ritualistic-
type behaviors that the individual is unable to keep
from doing(compulsions).
The person may try to suppress these thoughts or
behaviors but is unable to do so.
The individual knows that the thoughts or
behaviors are irrational but feels powerless to stop.
3. OBSESSIONS:- Obsessions are recurrent and persistent thoughts, impulses, or
images that cause distressing emotions such as anxiety or disgust. These intrusive
thoughts cannot be settled by logic or reasoning. Typical obsessions include
excessive concerns about contamination or harm, the need for symmetry or
exactness, or forbidden sexual or religious thoughts.
DEFINITIONS
COMPULSIONS:- Compulsions are repetitive behaviors or mental acts that a
person feels driven to perform in response to an obsession. The behaviors are
aimed at preventing or reducing distress or a feared situation. Although the
compulsion may bring some relief to the worry, the obsession returns and the cycle
repeats over and over. Some of the common compulsions include cleaning,
repeating, checking, ordering and arranging , Mental compulsions etc.
4. DEFINTION OF OCD Obsessive:- Compulsive Disorder (OCD) is a common,
chronic and long-lasting disorder in which a person has uncontrollable,
reoccurring thoughts (obsessions) and behaviors (compulsions) that he or she
feels the urge to repeat over and over.
An obsession is defined as an idea, impulse, or image which intrude into the
conscious aware repeatedly.
5. EPIDEMLOLOGY
CURRNT ESIMATES OF lifetime prevalence are generlly in the range of 1.7 -
4% .
OCD appears to have a simillar prevalence in different races and ethnicities .
Symptoms usually begin in individuals aged 10 -24 years .
The overallprevalence of OCD is equal in males and females .
6. CAUSES OF THE DISORDER
• GENETIC
• INFECTIONS
• OTHER NEUROLOGICAL CONDITONS
• STRESS
• INTERPERSONAL RELATIONSHIPS
• BIOLOGICAL FACTORS
• PSYCHOANLYTICAL THEORY
• BEHAVIOR THEORY
• NEUROANATOMICAL FACTORS
7. CAUSES OF THE DISORDER
The cause of OCD is not Known ; however , the following factors are relevant :
1. Genetic :
• twin studies have supported strong heritability for ocd , with a
genetic influence of 45-65% in studies in children , and 27 – 47 %
in adults .
• monozygotic twins may be strikingly concordant for ocd (80-87 %
, compared with 47-50 % concordance in dizygotic twins .
• several genetic studies have supported linkages to a varity of
serotonergic , dopam- inergic and glutamatergic genes .
2. Infections : It has been hypothesized that streptococal infections trigger a CNS
autoimmune response that results in neuropsychiatric symptoms .
3. Other neurological conditions : rare reports exist of OCD presenting as a
manifestation of neurologic insults such as brain trauma , stimulant abuse ,
carbon monoxide poisoning .
4. Stress : OCD symptoms can worsen with stress : however , stress does not
appear to be an etiologic factor .
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5. Interpersonal relationships :
• OCD symptoms can interact negatively with interpersonal relationships , and
families can become involved with illness in a counterproductive (opposite)way .
• Parenting style or upbringing does not appear to be a causative factor in OCD .
6. Biological Factors:
• People with a first degree relative (parent or sibling) with OCD have a
5 times greater risk of having the illness.
• identical twins have more chances of developing OCD as compared to
dizygotic twins.
7. Psychoanalytical Theory:
According to the Frued’s psychoanalytical theory OCD arises when
unacceptable wishes and impulses from the individual are only partially repressed.
They cause anxiety. Ego defense mechanisms are used to reduce the anxiety. These
defense mechanisms are used unconsciously in the form of acts, such as hand
washing.
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8. Behavior Theory:
This theory explains Obsessions as a conditioned stimulus to
anxiety. Compulsions have been described as learned behavior that decreases the
anxiety associated with the Obsessions. This decrease in anxiety positively
reinforces the compulsive acts and they become stable learned behavior.
9. Neuroanatomical Factors:
• there is evidence of abnormal brain structure and activity in
patients with OCD.
• these abnormalities are found in the pathway linking the lobes
(responsible for judgment) with the basal ganglia (which are part of the system
frontal for planning behavior) .
• Serotonin deficiency – OCD sufferers have too little serotonin for
their nerve cells to communicate effectively .
10. CLASSIFICATION OF OCD ICD-10
classifies OCD into 3 clinical subtypes according to the symptoms:
1. Predominantly obsessive thought or rumination.
2. Predominantly compulsive acts.
3. Mixed Obsessional thoughts and acts.
11. SIGNS & SYMOTOMS
Common obsessions include the following :
• Contamination .
•Safety .
•Doubting one ‘ s memory or perception .
•Need for order or symmetry .
•Unwanted intrusive sexual / aggressive thought .
Common compulsions include the following :
Cleaning / washing
Checking ( checking locks , stove ,iron ,safety of children .
Arranging objects .
Touching / tapping objects .
Hoarding (to collect and store large quantities of something , often secretly)
12. Symptoms of Obsessions
Repeated thoughts about
contamination(e.g. may lead to
fear of shaking hands or touching
objects).
Repeated doubts(e.g. repeatedly wondering
if they locked the door or turned
off an appliance).
13. A need to have things in a certain order(e.g. feels
intense anxiety when things are out of place).
16. Symptoms of Compulsion
Washing and cleaning(e.g. excessive hand washing
or house cleaning).
Counting (e.g. counting number of times that
something is done).
17. Checking (e.g. checking something that one has
done, over and over).
Requesting or demanding assurances from others.
18. Compulsion cont…
Repeating actions(e.g. going in and out of door or up
and down from a chair).
Ordering(e.g. arranging and rearranging cloths or
other items).
19. Note : the obsessions and compulsions seem to be
worse in the face of emotional stress.
20. DIAGNOSIS OF OCD
• Suggested by demonstration of realistic behavior that is
irrationl or excessive.
• MRI and CT shows enlarged Basal Ganglia in some
patients.
• PET(Positron emisaion Tomography) shows incresed
glucose metabolism in part of the basal ganglia.
• ICD-10 criteria .
25. TREATMENT
1 . PHARMACO THERAPY :-
• 5 – HT reuptake inhibitors , such as the SSRIs ( fluoxetine ,
fluvoxamine , sertraline , paroxetine , citalopram , escitaloparm ).
• clomipramine ( Anafranil ) , with possible alteratives including
veniafaxine , a sero- fonin norepinephrine reuptake inhibitor (SNRI ) .
• Addition of an NE reuptake inhibitor , such as desipramine , to an
SSRI , or trail of venlafaxine .
• Addition of a typical or atypical antipsychotic , especially in patients
with a history of tics .
• Augmentation with buspirone .
• Addition of inositol .
• Sole or augmented use of selected glutamtergic agents .
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2. BEVIOR THERAPY :-
• This is a frist – line treatment that should be underrtaken .
• Exposure and respo prevention( ERP ) is the important and specific core
element in behavior therapy for OCD .
3. MEDITATION & RELAXATION THERAPY
4. PSYCHODYNAMIC PSYCHOTHERAPY :-
This can be used for the patients who are psychologically oriented. The therapy
is based on psychoanalysis in which the patient is made conscious about their
unconscious thoughts and motivations thus gaining insight.
27. COGNITIVE BEHAVIOR THERAPY :-
During treatment sessions, patients are exposed to the
situations that create anxiety and provoke compulsive behavior or mental rituals.
Through exposure, patients learn to decrease and then stop the rituals that
consume their lives. They find that the anxiety arising from their obsessions lessens
without engaging in ritualistic behavior. This technique works well for patients
whose compulsions focus on situations that can be re-created easily.
28. PHARMACOLOGICAL TREATMENT
1. Benzodiazepines:-
• Alprazolam(0.5-1mg/day)
• Clonazepam(0.25-0.5 mg/day)
2. Antidepressants :-
Clomipramine(75-300mg/day)
Fluoxetine(20-80mg/day)
Fluvoxamine(50-200mg/day)
3. Antipsychotics :-
these are occassionally used in low doses in the treatment of severe anxiety
e.g. Haloperidol,Risperidine, Olanzepine.
29. ELECTRO-CONVULSIVE THERAPY
Electroconvulsive Therapy (ECT)In the presence of severe depression with OCD,
ECT may be needed. ECT is particularly indicated when there is a risk of suicide
and/or when there is a poor response to the other modes of treatment.
SELF-HELP AND COPING
Keeping a healthy lifestyle and being aware of warning signs and what to do if
they return can help in coping with OCD and related disorders. Also, using basic
relaxation techniques, such as meditation, yoga, visualization, and massage, can
help ease the stress and anxiety caused by OCD