2. Goal of oxygen therapy is to achieve adequate tissue
oxygenation
Inadequate oxygenation can lead to localised vasodilation,
pulmonary vasoconstriction, metabolic acidosis, tissue
necrosis, & brain injury
3. Indications
● In documented or suspected hypoxemia
● With PaO2 <60mmHg & SpO2<94% in room air
● Pulse oximetry is used to detect hypoxemia
● If not available - look for clinical signs
4. Clinical signs suggestive Of hypoxemia
● Central Cyanosis
● Nasal flaring
● Grunting
● Inability to drink or feed due to resp distress
● Depressed mental state and sensorium - drowsy and lethargic
● Severe lower chest wall restrictions
● Resp rate ≥ 70/ min
● Head nodding ( synchronized with respiration)
● Other signs like seizures, coma, acute neurological problems,
5. Modes of administration of oxygen
Variable performance device
Or low flow system
● Provide only a fraction of
patient’s inspiratory flow need
or tidal volume rest is met by
dilution with room air
● Oxygen flow rate - <10L/min
Fixed performance device Or
high flow system
● Provide all the inspiratory
flow requirements & tidal
volume
● Can deliver either high or low
FiO2
● Oxygen flow rate- >15L/min
6. ● Rate of oxygen flow is less than
patients inspiratory flow
● Results in mixing of O2 with
room air
● Deliver variable FiO2 (23-50%)
Suitable for Patients requiring low to
moderate FiO2(30-60%)
Having stable breathing pattern
● Delivers FiO2 - 100%
● delivers constant FiO2
● Used in emergency settings
Does not affected by patients
Inspiratory pattern
Suitable for patients requiring
consistent FiO2 >70%
Having varying breathing pattern
8. Variable performance device
● Nasal prongs/ cannula
Ends in 2 short tapered tubes , lie within the nostrils
Humidification not required
Avg FiO2 provided with 1 L/ min is 24%
With every increase of 1 L/min of O2 upto 4L/min FiO2 rises by 4%
Oxygen flow rate - for neonates 0.5-1L/min , infants 1-2 L/ min,
older children-1-4L/min
High flow cause irritation and dryness of nasopharynx
10. SIMPLE OXYGEN MASK
● Provide 35-60% FiO2
● At oxygen flow of 6-10L/ min
● With each L increase in oxygen FiO2 increase approximately by 10%
● Flow <5 L/min cause CO2 retention
12. Partial rebreathing MASK
● Provide 35-70% FiO2 at oxygen flow rate of 6-15L/ min
● Have extra reservoir and side ports
● Oxygen flow should be maintained such tht only ⅓ rd of reservoir get
empty during inspiration.
● During expiration, first 1/3rd of exhaled air enters the reservoir
14. Non rebreathing mask
● Provide FiO2 up to 80-100% at OFR of 8-15 L/ min
● It has one way valve between the mask & reservoir, also over the
exhalation port
● During inspiration port valve close & reservoir valve open
● During expiration, port valves open and reservoir valve close
16. Nosopharyngeal catheters
● Passed to pharynx just below the level of uvula
● Better oxygenation with a lower oxygen flow than nasal canula
● Because FiO2 in trachea is relatevly high with positive End Expiratory
pressure(PEEP) production
18. Fixed performance device
Oxygen hoods, incubators and tents
noninvasive methods
Minimal risk of airway obstruction by mucus or of gastric distention
● Humidification not necessary
● CO2 toxicity can occur if flow of oxygen inadequate
● CO2 retained if hood is used w/o tight seal around infronts neck
● Flow rate of 2-3 L / kg/min necessary to avoid rebreathing of CO2
with the hood
19. ● All these require high OFR to achieve adequate concentration of Oxygen and
avoid CO2 accumulation
● Oxygen hood interfere with feeding
● Expensive
23. Venturi mask
● It combines O2 with room air to give high flow oxygen at fixed and constant
FiO2
● Color coded jets are attached to the mask to deliver required amount of
oxygen
● It can deliver FiO2 ranging from 24-50%
● Recommend flow rate is 12-15 L/ min