Basics of Pain
Assessment and
Management
1
Learning Objectives
1. Understand the importance of pain recognition, assessment
and re-assessment.
2. Discuss the multi-factorial determinants of pain.
3. Identify the different classifications of pain and how this
impacts treatment selection.
4. Discuss the key elements of performing an accurate pain
history and examination.
5. Understand the different types of pain scales.
6. Describe the consequences of untreated pain.
7. Recognize patient safety issues regarding pain management,
discharge planning, and transitions of care.
5
Consider these case scenarios throughout the module
A 54 year-old non-English speaking male is brought to the ED by EMS after sustaining a motorcycle collision
approximately 20 minutes prior to arrival; he is calm and reports mild pain. Simultaneously, a 23 year-old
female that was involved in the same accident is brought to the ED. She was the restrained backseat passenger
in a pick-up truck; reports “pain all over” and is crying hysterically.
A 3 year-old right-handed male presents with his caregiver who reports that the child has complained of pain
in his right arm since yesterday. When questioned the child denies pain but cries and pulls away when any part
of the right upper extremity is touched. He has no obvious deformity or swelling to either arm.
A 53 year-old male with chronic back pain underwent knee replacement one week ago. He presents to his
primary care doctor complaining of persistent post-op pain. The patient reports his prescribed opioid is not
controlling his pain The pain is limiting his ability to perform his daily activities of living.
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1. Introduction to Pain
Management
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Why is Pain Management Important?
• Pain is a complex and common complaint that leads to frequent access of the US
healthcare system.
• Chronic pain alone affects more Americans than diabetes, cancer, and heart disease
combined, with an estimated annual cost of $600 billion.
• Pain is often under recognized leading to inadequate management and numerous
patient safety concerns, particularly in special populations and minority groups.
• Untreated acute pain may lead to adverse sequelae.
• With the recent opioid epidemic and advances in pain research, there is a renewed
emphasis on early multimodal pain management, nonpharmacologic options and
nonopioid alternatives.
General Pain Management Challenges
(part 1)
• Failure to recognize or differentiate pain from anxiety
• Lack of education for healthcare providers, especially regarding nonpharmcologic
modalities.
• Safety concerns, fear of patient addiction or prescription legal repercussions
• Lack of pre-existing physician-patient relationships i.e. knowledge of past medical
history
• Inadequate discharge pain plans resulting in return visits or admissions
• Pressure to see patients rapidly, especially those perceived to be more critical,
which can hinder time for adequate pain assessments and re-assessments
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General Pain Management Challenges
(part 2)
• Physiologically unstable patients are least likely to receive a
standardized pain assessment and to receive pain medications
• Outpatient settings may have limited time to perform full pain
assessments or to evaluate for psychosocial contributors to pain
(e.g. financial stress, impaired sleep, anxiety, etc.)
• Stereotypes towards patients with chronic pain being drug-
seekers
• Analgesic shortages leading to medication errors and changing
protocols
• And many more!
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Challenges Summary- Keeping Balance
• Healthcare providers face the dilemma of balancing safe
opioid/analgesic prescribing and high-risk patient recognition with
appropriate pain management strategies for those in significant pain
while being mindful of different types of pain, individual pain factors
and comorbidities.
Cognitive
Functioning
Genetics
Religion
Clinical
How Does Pain Affect Us?
• Pain is multidimensional, affecting people
physically, psychologically, socially and
spiritually.
• Patients’ responses to pain may be related to:
• genetics, age, gender, ethnicity,
socioeconomic and psychiatric factors,
catastrophizing, culture, religion,
previous experiences, patient
perceptions and expectations, etc.
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Pain
Demographics
Cognitive
Functioning
Genetics
Culture
Psycho-
social
Religion
Clinical
• A patient’s response to prescribed pain treatment can be influenced by
factors unrelated to actual pharmacological treatments.
These factors include:
– Perceived effective communication with physicians and nurses by the patient
– Perceived responsiveness by the treating team
– Perceived empathy by the treating team
Patient Perceptions
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Factors Affecting Patient Response To Painful Stimuli
• Age, Gender, Ethnicity
• Socioeconomic and Psychological factors
• Catastrophizing
• Culture and Religion
• Genetics
• Previous experiences
• Patient perceptions
• Patient expectations
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Patient Response to Pain and Management:
Age and Gender
• Demographics such as age, gender,
race and ethnicity have all been
reported to influence pain
perception.
• Studies on the influences of gender
and age have had variable results.
• Overall, patients who identify as
female display more sensitivity than
males towards most painful
conditions. Females also are
believed to express their pain more
frequently and effectively than
males.
• Studies have shown different
interpretations by observers for the
same facial expressions depending
on patient gender.
• This behavior could explain why
patients are managed differently
by providers when presenting with
the same injury or painful
condition.
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Patient Response to Pain and Management:
Ethnicity
• Ethnicity is associated with pain intensity and interference.
– One study found African Americans to report higher rates of pain and
interference with daily activities such as sleep.
Consider the impact of age, gender and ethnicity on pain assessment and
management but beware of labeling or stereotyping- treat the individual patient! 18
Patient Response to Pain and Management:
Culture and Religion
• Culture and Religion/Personal Values/Coping
Mechanisms
– How patients cope with pain can be influenced by their
existing social support system.
– Those with strong cultural and religious ties tend to have
stronger support mechanisms for dealing with their pain.
– Variations in cultural norms can influence how a patient
expresses their pain and how they want their pain to be
managed.
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Patient Response to Pain and Management:
Socioeconomic and Psychological Factors
• Health disparities research indicates that patients living in rural areas
and who are of lower socioeconomic status tend to report higher levels
of chronic pain, pain related disability, and depression. Depression and
pain often co-exist (30-60% of pain patients also report depression).
• Previous pain experiences can alter activity within certain brain regions
responsible for pain processing resulting in persistent pain.
• Additionally, mood disorders and other psychiatric disorders have been
linked to the development of chronic pain. This co-existence has
important clinical and financial implications. These patients often
report more pain, greater functional disability, worse clinical prognosis,
and accrue higher healthcare costs.
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Patient Response to Pain and Management:
Pain Catastrophizing
• Pain catastrophizing is an
exaggerative cognitive response to
an anticipated or actual painful
stimulus and affects how
individuals experience and express
pain.
• People who catastrophize tend to
magnify their pain, ruminate
about their pain, and feel helpless
in managing their pain.
• Pain catastrophizing shares
similarities with depression and
anxiety. It has been associated with
pain-related outcomes such as pain
severity, activity interference and
disability, depression, changes in
social support networks, more
frequent healthcare visits, and
opioid usage.
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Examples Of Catastrophizing
• Magnification: the response that
symptoms that can be or are greater
than expected. Ex: “I´m afraid that
something serious might happen”
• Rumination: when an individual
focuses repeatedly on attributes of
an event that evoke a negative
emotional response. Ex: "I can´t stop
thinking about how much it hurts“
• Helplessness: the belief that there is
nothing that anyone can do to
improve a bad situation. Ex: "There is
nothing I can do to reduce the
intensity of my pain".
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• Genetic polymorphisms play an integral role in how patients respond to painful
stimuli and treatment.
• For example, populations within certain ethnic groups are known to carry genetic
mutations of the liver CYP450 enzymes responsible for drug metabolism.
• Some patients are “ultra-rapid metabolizers” of certain drugs such as codeine. This means
they convert codeine to morphine more rapidly than other patients, resulting in potential
supra-therapeutic dosing.
• Some patients are “slow metabolizers” and do not efficiently metabolize codeine, and thus
never achieve therapeutic levels.
• Caucasian and African American populations have approximately equal
proportions of fast and slow metabolizers, whereas nearly 90% of certain Asian
groups are fast acetylators.
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Patient Response to Pain:
Genetics
2. Defining and
Classifying Pain
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Classification of Pain
• Determining the context, history of present illness and type of pain is
complex and time consuming but is essential to developing a
successful management plan.
• Pain may be classified by underlying etiology, anatomic location,
temporal nature, and intensity.
• Underlying etiology refers to the source of the experienced pain.
• Anatomic location refers to the site of pain within the body
• Temporal nature refers to the duration of the pain.
• Intensity refers to the degree or level of the pain experience .
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Pain
Underlying
Etiology
Nociceptive
Inflammatory
Neuropathic
Anatomic
Location
Somatic
Visceral
Temporal
Acute
Chronic
Acute on chronic
Intensity
Mild
Moderate
Severe
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• Nociceptive Pain is the result of direct tissue injury from a
noxious stimulus. Nociceptive pain can be further classified as
somatic or visceral pain.
• Examples include bone fracture, new surgical incision, and acute
burn injury.
• Inflammatory Pain is the result of released inflammatory
mediators that control nociceptive input and are released at
sites of tissue inflammation.
• Examples include appendicitis, rheumatoid arthritis, inflammatory
bowel disease, and late stage burn healing.
• Neuropathic Pain is the result of injury to nerves leading to an
alteration in sensory transmission. It can be central or
peripheral in nature.
• Examples include diabetic peripheral neuropathic pain, postherpetic
neuralgia, chemotherapy induced pain, and radiculopathy.
Underlying
Etiology
Nociceptive
Inflammatory
Neuropathic
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• Somatic Pain, also known as musculoskeletal pain,
is pain that occurs from injury to skin, muscle,
bone, joint, connective tissue and deep tissues.
Typically pain is well-localized, sharp and worse
with movement.
• Examples include lacerations, fractures, and pelvic pain.
• Visceral Pain is internal pain and typically occurs
from internal organs or tissues that support them.
Pain is usually poorly localized and described as
vague deep aches, colicky, and/or cramping.
• Examples include appendicitis, peptic ulcer disease,
diverticulitis, endometriosis, and ureteral stones. 28
• Acute pain is defined as lasting less than 3 months and is a
neurophysiological response to noxious injury that should
resolve with normal healing.
• Examples include post-operative pain, fractured bones, appendicitis,
crush injury to finger, labor and delivery pain.
• Chronic pain is defined as lasting more than 3 months or
beyond the expected course of an acute disease or after
complete tissue healing. Chronic pain extends beyond the
time of normal wound healing with the development of
multiple neurophysiological changes in the central nervous
system.
• Examples include low back pain, neck pain, and chronic pancreatitis.
• Acute on Chronic pain refers to times of acute exacerbations
of a chronic painful syndrome or new acute pain in a person
suffering from a chronic condition.
• Examples include a sickle cell exacerbation in a patient with sickle
cell disease or an abscess in a patient with sickle cell disease. 29
Pain intensity can range from: Scores typically range from:
Mild 1-4
Moderate 5-7
Severe 8-10
Pain Intensity is determined by pain assessment scores in combination
with history and physical exam. Pain intensity is subjective and may vary
from one patient to another. Pain Scales are used to assess and quantify
the intensity of a patients pain. Remember that each scale has its’ own
scoring range and levels for mild, moderate or severe pain intensity.
• Case scenario 1 is an example of the challenges involved in determining intensity
where one patient has severe injuries but rates their pain as moderate compared to
the patient with minor injuries who complains of severe “pain all over.”
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TYPES OF PAIN MECHANISM CINICAL EXAMPLES
PHARMACOLOGICAL
TREATMENT OPTIONS*
UNDERLYING ETIOLOGY
Nociceptive The result of direct tissue injury from a noxious stimuli.
Bone fracture, fresh surgical incision, and
fresh burn injury.
May include both opiate and non-opiate
medications depending on injury.
Inflammatory
The result of released inflammatory mediators that control
nociceptive input.
Late stages of burn healing, neuritis, and
arthritis
Anti-inflammatory agents
Neuropathic
The result of direct injury to nerves leading to an alteration in
sensory transmission.
Diabetic neuropathy, peripheral neuropathic
pain, and post-herpetic neuralgia.
Tricyclic, selective norepinephrine
reuptake inhibitors, gabapentinoids, or
antidepressants
Idiopathic Unknown
Chronic back pain without preceding trauma
or obvious inciting event.
May be difficult to adequately address
pain since underlying etiology is unknown,
especially in emergency settings.
ANATOMIC LOCATION
Somatic A-delta-fiber activity located in peripheral tissues
Superficial lacerations, superficial burns,
superficial abscess
Topical and/or local anesthetics, opiates,
non-opiates
Visceral C fiber activity located in deeper tissues such as organs
Uterine fibroid pain, pyelonephritis, biliary
colic
Opiates
TEMPORAL NATURE
Acute
A neurophysiological response to noxious injury that should
resolve with normal wound healing.
Acute fracture, acute knee sprain Opiate, non-opiates
Chronic
Pain that extends beyond the time for normal wound healing
with resultant development of multiple neurophysiological
changes
Chronic low back pain, fibromyalgia, arthritis Depends on the nature of the pain. Please
refer to the module on chronic pain for
more detailed information.
Acute-on-chronic An acute exacerbation of a chronic pain syndrome
Sickle cell disease, cancer, rheumatoid
arthritis, acute injury in chronic pain patient
*Nonpharmacologic management options should be considered at any time for any type of pain
Table 1. Types of pain, mechanism, and clinical examples
For more information on Nonpharmacologic Pain Management, please refer to the pdf or learning module
31
3. How to Perform a Pain
Assessment
a. Components of the Pain History
b. Pain Focused Physical Exam
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a. Components of the Pain History
33
Pain History Elements and Questions
Basics
1. Onset of recent pain
2. Aggravating and alleviating factors
3. Quality of pain experience
4. Location of pain
5. Severity of pain
6. Circumstances of original pain
The patient’s history and physical exam can be an invaluable source when it
comes to determining the proper diagnosis and course of treatment.
Essential elements should include a detailed history of the current pain and, for
those that suffer from chronic pain, their previous pain history.
Functionality
1. How is pain affecting current level
of function?
2. Is patient working?
3. How is patient coping with pain?
34
Pain History Elements and Questions
Psychosocial and psychiatric
1. Depression
2. Suicidal ideation or past suicide attempts
3. Past psychiatric admissions
4. Physical, sexual and/or emotional abuse.
Co-morbidities
1. Significant past medical and/or
surgical history
2. Chronic diseases (obesity,
hypertension, diabetes, etc. )
3. Psychosocial and/or psychiatric co-
morbidities
4. Family history of substance abuse
Consider using the mnemonics OPQRST, SOCRATES and QISS TAPED to assess pain.
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Pain History Elements and Questions
Essential elements of Pain History – Basics
Basic Elements Description
1. Onset of recent pain • When did the pain start and what was the patient doing when it started
• Was the onset sudden, gradual, or an exacerbation of a chronic problem
2. Aggravating and alleviating factors • What makes the pain better and what makes it worse?
• How does physical activity or position affect pain?
• Do any nonpharmacological therapies or medications relieve the pain?
3. Quality of pain experience • Ask the patient “Can you describe the pain?” Ideally, this will elicit
descriptions of the patient's pain: whether it is sharp, dull, crushing, burning,
tearing, or some other feeling, along with the pattern, such as intermittent,
constant, or throbbing.
4. Location of pain • Where pain is on the body and whether it radiates (extends) or moves to any
other area?
5. Severity of pain • Ask the patient to describe the intensity of pain at baseline and during acute
exacerbations, typically done using a pain scale
6. Circumstances of original pain • Identify when the pain started, under what circumstances, duration, onset
(sudden/gradual), frequency, whether acute/chronic.
36
Consider using a patient pain diagram at
check-in or triage (if stable)
37
Pain History Elements and Questions
Mnemonics for obtaining pain history
OPQRST
• Site
• Onset
• Character
• Radiation
• Associations
• Time course
• Exacerbating/Reli
eving factors
• Severity
SOCRATES
• Onset of event
• Provocation and
palliation of
symptoms
• Quality
• Region and
radiation
• Severity
• Timing
• Quality
• Impact
• Site
• Severity
• Temporal
• Aggravating and
alleviating
• Past response and
preferences
• Expectations and
goals
• Diagnostics and
physical exam
QISS TAPED
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OPQRST
O Onset of
event
• What was the patient doing when it started? Were they active, inactive, and or stressed?
• Did that specific activity prompt or start the onset of pain?
• Was onset of pain sudden, gradual or part of an ongoing chronic problem
P Provocation
and
palliation of
symptoms
• Is the pain better or worse with:
• Activity. Does walking, standing, lifting, twisting, reading, etc… have any effect of the pain?
• Position. Which position causes or relieves pain? Provide examples to the patient-- sitting,
standing, supine, lateral, etc…
• Adjuvant. Which type of medication relieves the pain (Tylenol, Ibuprofen, etc.. )? Does the use of
heat or ice packs alleviate pain? What type of alternative therapy (massage, acupuncture) have
you used before?
• Does any movement, pressure (such as palpation) or other external factor make the problem
better or worse? This can also include whether the symptoms relieve with rest.
Q Quality • Ask the patient to describe the quality of pain – is it throbbing, dull, aching, burning, sharp,
crushing, shooting, etc…?
• Questions can be open ended "Can you describe it for me?" or leading
• Ideally, this will elicit descriptions of the patient's pain: whether it is sharp, dull, crushing,
burning, tearing, or some other feeling, along with the pattern, such as intermittent,
constant, or throbbing. 39
OPQRST
R Region and
radiation
• Where pain is on the body and whether it radiates (extends) or moves to any other area? Referred
pain can provide clues to underlying medical causes.
• Location: body diagrams may help patients illustrate the distribution of their pain.
• Dermatome map – may help determine the relationship between sensory location of pain and spinal
nerve segment (see figure next slide).
• Referred vs Localized: referred pain (also known as reflective pain) is feeling pain in a location other
than the original site of the painful stimulus. Localized pain is when pain typically stays in one location
and does not spread.
S Severity • Ask the patient to describe the intensity of pain at baseline and during acute exacerbations.
• The pain score (usually on a scale of 0 to 10) where 0 is no pain and 10 is the worst possible pain. This
can be comparative (such as "... compared to the worst pain you have ever experienced") or
imaginative ("... compared to having your arm ripped off by a bear"). If the pain is compared to a prior
event, the nature of that event may be a follow-up question.
T Timing • Identify when the pain started, under what circumstances, duration, onset (sudden/gradual),
frequency, whether acute/chronic.
• How long the condition has been going on and how it has changed since onset (better, worse,
different symptoms)?
• Whether it has ever happened before, and how it may have changed since onset, and when the pain
stopped if it is no longer currently being felt?
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S Site Where is the pain? Or the maximal site of the pain.
O Onset When did the pain start, and was it sudden or gradual? Include also whether if
it is progressive or regressive.
C Character What is the pain like? An ache? Stabbing?
R Radiation Does the pain radiate anywhere? (See also Radiation.)
A Associations Any other signs or symptoms associated with the pain?
T Time course Does the pain follow any pattern?
E Exacerbating/Relieving
factors
Does anything change the pain?
S Severity How bad is the pain?
SOCRATES
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QISS TAPED
Q Quality What were your first symptoms? What words would you use to describe the pain? (achy, sharp, burning, squeezing, dull, icy, etc...)
Besides sensations you consider to be "pain," are there other unusual sensations, such as numbness?
I Impact How does the pain affect you?
How does the pain impact your sleep, activity, mood, appetite (other - work, relationships, exercise, etc.)
What does the pain prevent you from doing? (Depression screen) Do you feel sad or blue? Do you cry often? Is there loss of interest in
life? Decreased or increased appetite?
(Anxiety screen) Do you feel stressed or nervous? Have you been particularly anxious about anything? Do you startle easily?
S Site Show me where you feel the pain. Can you put your finger/hand on it?
Or show me on a body map?
Does the pain move/radiate anywhere? Has the location changed over time?
S Severity On a 0-10 scale with 0 = no pain and 10 = the worst pain imaginable, how much pain are you in right now?
What is the least pain you have had in the past (24 hours, one week, month)?
What is the worst pain you have had in the past (24 hours, one week, month)?
How often are you in severe pain? (hours in a day, days a week you have pain)?
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QISS TAPED
T Temporal Characteristics When did the pain start? Was it sudden? Gradual? Was there a clear triggering event?
Is the pain constant or intermittent? Does it come spontaneously or is it provoked?
Is there a predictable pattern? (e.g., always worst in the morning or in the evening? Does it suddenly flare up?)
A Aggravating and
Alleviating Factors
What makes the pain better? What makes the pain worse? When do you get the best relief? How much relief
do you get? How long does it last?
P Past Response,
Preferences
How have you managed your pain in the past? (Ask about both drug and non-drug methods)
What helped? What did not help? (Be specific about drug trials - how much and how long?)
What medications have you tried? Was the dose increased until you had pain relief or side effects? How long
did you take the drug?
Are there any pain medicines that have caused you an allergic or other bad reaction?
How do you feel about taking medications?
Have you tried physical or occupational therapy? What was done? Was it helpful?
Have you tried spinal or other injections for pain treatment? What was done? Was it helpful?
E Expectations, Goals,
Meaning
What do you think is causing the pain?
How may we help you? What do you think we should do to treat your pain?
What do you hope the treatment will accomplish?
What do you want to do that the pain keeps you from doing?
What are you most afraid of? (Uncovers specific fears, such as fear of cancer, which should be acknowledged
and addressed.)
D Diagnostics & Physical
Exam
Examine and inspect site, Perform a systems assessment and examination as indicated
Review imaging, laboratory and/or other test results as indicated 43
Pain History Elements and Questions
Medical and Surgical History
Medical or surgical issues related to patient’s pain or treatment may include:
Cancer • Different types of pain may be caused by multiple etiologies:
• Tumors: involvement of bone, vessels, nerves, body organs
• Diagnostic procedures: may be painful such as biopsies, lumbar punctures, or
venipuncture
• Treatment: radiation, chemotherapy, or surgical excision
Recent Surgery • Incisional pain
• Complications such as anastomotic leak, bleeding, compartment syndrome, etc..
Other Conditions • Diabetes which can lead to neuropathic pain
• Herpes zoster which can lead to radicular pain
• Migraines which can lead to mixed etiology
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Patient Factors to Consider When Assessing Pain
Assessing pain in certain special populations can be challenging and
requires multiple considerations such as:
• Age
• Level of development
• Communication skills/language
• Cognitive skills
• Prior pain experiences
• Associated beliefs
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Medical and Pain Communication Cards
Download and print your own set here
Medical Communication Cards or scan the QR code
Communication cards are used
to assist healthcare providers
in communicating with scared,
nonverbal or non-English
speaking patients and families!
• History taking and
assessment
• Pain, mechanism of injury
• Explanation of treatments
• Procedures and testing
• Discharge instructions
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b. Pain Focused Physical Exam
47
During initial pain assessment, physical examination of the patient should be conducted.
Pain Assessment: Physical Examination
You should be examining the
patient’s:
Examples
Appearance obese, emaciated, histrionic, flat affect
Posture splinting, scoliosis, kyphosis
Gait antalgic, hemiparetic, using assisting devices
Facial Expression grimacing, tense, diaphoretic, anxious
Vital Signs sympathetic overactivity, temperature asymmetries
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Pain Assessment: Physical Examination
You should be examining
the Painful Area(s):
Example
Inspection • Skin: color changes, hair loss, flushing, goose bumps, sweating
• Muscle: atrophy or spasm
• Edema
Palpation • Demarcation of the painful area
• Detection of changes in pain intensity within the area
• Trigger points
• Changes in sensory or pain processing
Musculoskeletal system • Flaccidity: extreme weakness (may be from paralysis)
• Abnormal movements: neurologic damage or impaired sense of proprioception,
reduced sense of light touch
• Limit range of motion: disc disease, arthritis, pain
Neurological exam • Cranial nerve exam
• Motor strength
• Spinal nerve function: deep tendon reflexes, pinprick, proprioception
• Coordination: Romberg’s test, toe-to-heal, finger-to-nose, rapid hand movement
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Pain Assessment: Physical Examination
1. Note the patient’s vital signs as they
can provide a clue to pain severity
• An elevation in blood pressure and heart
rate can occur secondary to pain and
inadequate control of pain.
• However, normal vital signs should not
negate a patient’s reported pain. Always
review vital signs.
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2. Take cues from your patient
• Patients will often assume a position of comfort.
• Observe vocalizations (crying child), facial expressions, body posture,
movements, and motor response (decreased movement).
• Observe physiological clues such as skin flushing, diaphoresis, and/or vital
sign abnormalities.
• Consider the patient’s baseline mental status. Are they able to effectively
communicate their pain to you?
• Perform a focused exam taking into account the information given by the
patient. The exam should also assess the patient’s functionality.
• A sensory exam should always be conducted in patients with pain especially
neuropathic pain.
Pain Assessment: Physical Examination
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4. Pain Assessment Scales
a. Adult Pain Assessment Scales
b. Pediatric Pain Assessment Scales
52
Pain Assessment Scales
As a healthcare provider, it is essential to know and understand which pain assessment
tools and scales are used in your institution.
• Pain scales are typically applied to all pain types. However, chronic and cancer-related pain may
require more complex evaluation tools.
• Although pain is multi-factorial, the majority of pain scales assess pain intensity.
• There are different validated pain scales available for a variety of patient populations such as:
 adults
 pediatrics
 elderly
 non-verbal
• Not all pain scales are equal and one should be chosen based on the patient.
• For example, it would be inappropriate to use a pain scale intended for
adults, such as the Defense and Veterans Pain Rating Scale 2.0, when
assessing a three-year-old child.
53
Pain Assessment Using Pain Scales
• Once a pain scale is chosen, interpretation of the score is not so straightforward.
• There is no defined score or threshold for what score correlates to actual pain and to what
intensity the pain is felt by the patient.
• Using the same scale for two different patients doesn’t allow for comparison of pain
intensity. For example, a patient with a score of 9 on the Numerical Rating Scale may not
necessarily be experiencing more pain than one with a score of 6 on the same scale.
• Because of the subjective nature of standardized pain scales, patient functionality may be the
best indicator of pain intensity.
• Pain scales DO NOT take into account patient genetics, past experiences,
comorbidities, or other pain influencing factors.
• In patients with preexisting pain it is important to determine their baseline pain
level.
Select a scale and be consistent! 54
Pain Assessment Using Pain Scales
• When using a pain scale in a verbal adult it is best to ground the scale by
providing context for the patient.
• For example, ask the patient at which level on the pain scale would they take an over-the-
counter pain medication? For those with chronic pain, what level of pain do they experience
every day?
• Surrogate reporting (pain history obtained from a parent, caregiver or loved one)
of a non-verbal patient’s pain and behavior or activity changes can also aid in
pain assessment.
• Try to determine who really provides the patient’s daily care and is knowledgeable about
their history, disease, and past pain management or experiences.
Don’t forget that abnormal vital signs or a change in vital
signs can also serve as an indirect marker for pain.
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Pain Scales* Verbal, Alert and Oriented Non-verbal, GCS <15 or Cognitive Impairment
Adult 1. Verbal Numeric Scale (VNS)/
Numeric Rating Scale (NRS)
2. Visual Analogue Scale (VAS)
3. Defense and Veterans Pain
Rating Scale (DVPRS 2.0)
1. Adult Non-Verbal Pain Scale (NVPS)
2. Assessment of Discomfort in Dementia (ADD)
3. Behavioral Pain Scale (BPS)
4. Critical-Care Observation Tool (CPOT)
Pediatric 3 yo and older
1. Wong Baker Faces
2. Oucher (3-12yrs)
3. Numerical Rating Scale (NRS)
(7-11yrs)
8 yo and older
1. Visual Analogue Scale (VAS)
2. Verbal Numeric Scale (VNS)/
Numeric Rating Scale (NRS)
Birth – 6 mos
1. Neonatal Infant Pain Scale (NIPS)
2. Neonatal Pain Assessment and Sedation Scale (N-PASS)
3. Neonatal Facial Coding System (NFCS)
4. CRIES
Infant and older
1. Revised Faces, Legs, Activity, Cry, and Consolability
(r-FLACC)
2. Non Communicating Children’s Pain Checklist (NCCPC-R)
3. Children’s Hospital of Eastern Ontario Pain Scale (CHEOPS)
(ages 1-7)
Examples of Pain Scales
56
*This is a short list of pain scales. Determine which pain assessment tools are used by your agency or facility.
To learn more about the different scales, visit PAMI
56
a. Adult Pain Assessment Scales
57
Adult Pain Scales: Verbal, alert and oriented
Measurement Scale Description
Verbal Numeric Scale (VNS)/
Numeric Rating Scale (NRS)
Self-report scale. Eleven point scale that requires understanding of numbers, addition and
subtraction.
Verbal rating scale (VRS)
Five pain levels are indicated in large print on a sheet give to the patient: no, pain, mild pain,
moderate pain, severe pain, unbearable pain.
Visual Analogue Scale
A 100-mm rule with a movable cursor: “no pain” is written at he left end of the horizontal line
along which the cursor is moved, and “maximal pain” at the right end.
Defense and Veterans Pain
Rating Scale 2.0 (DVPRS)
Self-report scale. Eleven point scale that requires the patient to identify pain by numerical
rating, color intensity, facial expression, and pain disruption. Followed by four supplemental
questions evaluating the biopsychosocial impact of pain.
58
Verbal Numeric Scale (VNS)
Numeric Rating Scale (NRS)
59
Defense and Veterans Pain Rating Scale 2.0
(DVPRS)
60
Measurement Scale Description
Adult Non-Verbal Pain Scale
(NVPS)
Behavioral scale. Based on FLACC scale and contain behavioral dimensions and physiology
dimensions that are graded by severity.
Pain Assessment in Advanced
Dementia (PAINAD) Scale
Assesses pain in patients with dementia. Total scores range from 0 to 10 (based on a scale of 0 to
2 for five items: breathing. Vocalization, facial expression, body language, and consolability),
higher score indicates more severe pain
Behavioral Pain Scale (BPS)
Behavioral scale. Three observational items (facial expression, upper limbs, and compliance with
ventilation). Higher score, greater discomfort.
Critical-Care Observation Tool
(CPOT)
Behavioral scale. Used for intubated and nonintubated critical care patients. Four domains (facial
expressions, movements, muscle tension, and ventilator compliance. Higher score, great pain
level
Adult Pain Scales: Non-verbal, GCS <15 or
Cognitive Impairment
61
Adult Non-Verbal Pain Scale (NVPS)
62
Pain Assessment in Advanced Dementia (PAINAD)
Scale
63
Behavioral Pain Scale (BPS)
Payen JF, Bru O, Bosson JL, Lagrasta A, Novel E, et al. Assessing pain in critically ill sedated patients by using a
behavioral pain scale. Crit Care Med. 2001; 29:2258-2263.
64
Critical-Care Observation Tool (CPOT)
65
b. Pediatric Pain Assessment Scales
66
Pediatric Pain Scale Descriptions
Measurement Scale Age Range Description
Birth - 6 months
Neonatal Infant Pain Scale (NIPS) Preterm and full term neonates Behavioral scale.
Neonatal Pain Assessment and
Sedation Scale (N-PASS)
Preterm and full term neonates Behavioral and physiologic scale.
Neonatal Facial Coding System (NFCS) 32 weeks gestation to 6months
Facial muscle group movement, brow budge, eye squeeze, nasolabial
furrow, open lips, stretch mouth lip purse, taut tongue, and chin
quiver
CRIES 32 weeks gestation to 6 months Behavioral and physiologic scale.
Infant and older (non-verbal children)
Faces, Legs, Activity, Cry, and
Consolability (FLACC)
2 months to 7 years, critically ill, cognitively
impaired, and older than three years of age
unable to utilize a self-report scale.
Behavioral scale. Scored in a range of 0–10 with 0 representing no
pain. The scale has five criteria, which are each assigned a score of 0, 1
or 2.
Non Communicating Children’s Pain
Checklist (NCCPC-R)
3-19 years (with cognitive impairment)
30 items that assess seven dimensions: vocal, eating/sleeping, social,
facial, activity, body/limb, and physiologic signs
3 years and older
Wong Baker Faces 3 years and older
Self-report scale. Please refer to specific references for those
alternative face scales.
Oucher 3 -12 years
Self-report tool consisting of a vertical numerical scale and a photo
scale with expressions of “hurt” to “no hurt.”
8 years and older
Visual Analogue Scale (VAS)
8 years and older Self-report scale. Consists of pre-measured vertical or horizontal line,
where the ends of the line represent extreme limits of pain intensity.
Requires understanding of numbers, addition and subtraction.
Verbal Numeric Scale (VNS)/ Numeric
Rating Scale (NRS)
8 years and older
Self-report scale. Eleven point scale that requires understanding of
numbers, addition and subtraction.
67
Pediatric Pain Scales:
Birth to 6 months
Measurement Scale Age Range Description
Birth - 6 months
Neonatal Infant Pain Scale
(NIPS)
Preterm and full term neonates Behavioral scale.
Neonatal Pain Assessment
and Sedation Scale (N-PASS)
Preterm and full term neonates Behavioral and physiologic scale.
Neonatal Facial Coding
System (NFCS)
32 weeks gestation to 6months
Facial muscle group movement, brow budge, eye
squeeze, nasolabial furrow, open lips, stretch mouth
lip purse, taut tongue, and chin quiver
CRIES 32 weeks gestation to 6 months Behavioral and physiologic scale.
68
Neonatal Infant Pain Scale (NIPS)
The NIPS (Lawrence et al., 1993) was developed at Children’s Hospital of Eastern Ontario. The NIPS assesses six behavioral indicators in response to
painful procedures in preterm newborns (gestational age < 37 weeks) and full-term newborns (gestational age > 37 weeks to 6 weeks after delivery).
69
Neonatal Pain Assessment and Sedation Scale
(N-PASS)
70
Pediatric Pain Scales:
Infant and older (nonverbal children)
Measurement Scale Age Range Description
Infant and older (non-verbal children)
Faces, Legs, Activity, Cry,
and Consolability (FLACC)
2 months to 3 years,
critically ill, cognitively
impaired, and older than
three years of age unable to
utilize a self-report scale.
Behavioral scale. A revised FLACC (r-FLACC)
was developed for children with cognitive
impairment (CI). It contains the same core
components as the original FLACC.
Non Communicating
Children’s Pain Checklist
(NCCPC-R)
3-19 years (with cognitive
impairment)
30 items that assess seven dimensions: vocal,
eating/sleeping, social, facial, activity,
body/limb, and physiologic signs
Children’s Hospital of
Eastern Ontario Pain
Scale (CHEOPS)
1-7 years
Observational scale for measuring
postoperative pain in children.
71
Faces, Legs, Activity, Cry, and Consolability
(FLACC)
72
Children’s Hospital of Eastern Ontario Pain Scale
(CHEOPS)
73
Pediatric Pain Scales:
3 years and older
Measurement
Scale
Age Range Description
3 years and older
Wong Baker Faces 3 years and older
Self-report scale. Please refer to
specific references for alternative face
scales.
Oucher 3 -12 years
Self-report tool consisting of a vertical
numerical scale and a photo scale
with expressions of “hurt” to “no
hurt.”
74
Wong Baker Faces
75
Pediatric Pain Scales:
8 years and older
Measurement Scale Age Range Description
8 years and older
Visual Analogue Scale
(VAS)
8 years and older
Self-report scale. Consists of pre-measured vertical or
horizontal line, where the ends of the line represent
extreme limits of pain intensity. Requires understanding
of numbers, addition and subtraction.
Verbal Numeric Scale
(VNS)/ Numeric Rating
Scale (NRS)
8 years and older
Self-report scale. Eleven point scale that requires
understanding of numbers, addition and subtraction.
76
Verbal Numeric Scale (VNS)/ Numeric Rating Scale
(NRS)
77
5. Management of Pain
a. General principles of pain management
b. Re-assessment of pain
c. Consequences of Unrelieved Pain
78
a. General Principles of Pain Management
- Stepwise approach
- Pharmacologic management
- Nonpharmacologic modalities
- Patient safety considerations
- Tranisitions of care and discharge planning
79
General Principles of Pain Management
In this section general principles of pain management will be reviewed.
Due to the changing landscape of pain management, specific
pharmacological and nonpharmacologic treatments will not be
discussed.
For more detailed information on specific pain
management, therapies and treatments refer to the
other PAMI modules, PAMI stepwise approach and the
PAMI Pain Management and Dosing Guide.
80
Pain Management: Putting it All Together
• No Perfect Recipe or “Cookbook”
• No Universal Recipe
Overview of PAMI Stepwise Approach to Pain
(Adapted to Setting- ED, Hospital, EMS)
Ideal approach not always possible
Step 7. Monitoring & Discharge Checkpoint
Step 6. Management Checkpoint
Step 2. Developmental or Cognitive Checkpoint
Step 3. Family Dynamic Checkpoint
Step 1. Situation Checkpoint
Step 5. Patient Assessment Checkpoint
Step 4. Facility Checkpoint
Pain Management brings challenges to
healthcare. The choice of tools you use
can be determined by using a stepwise
approach that is outlined next.
Step 1: Determine the Situation: What are you
trying to accomplish or manage?
• Pain only
• Pain and anxiety or agitation
• Anxiety only
• Agitation only
• Procedure that will induce pain or anxiety- transport, IV,………
• Chronic pain condition exacerbation
Determination accomplished after triage, history, and exam
Step 1. Situation Checkpoint
Step 2: Perform a Developmental Checkpoint
• What is the developmental stage of patient?
• Is development normal for age?
• Developmental delay
• Autism
• Special health care needs
• Mental health concerns
• Recent traumatic events
• Regression to lower developmental stage
What are characteristics of developmental stage in response to pain?
How do you adapt your approach based on developmental level?
Step 2. Perform a Developmental or Cognitive Checkpoint
Responses to Pain by Age or Development
Age Group Understanding of Pain Behavioral Response Verbal Description
Preschoolers
3–6 years
(preoperational)
Pain is a hurt; Does not relate pain to illness; may relate pain to an
injury; Often believes pain is punishment; Unable to understand
why a painful procedure will help them feel better or why an
injection takes the pain away
Active physical resistance, directed aggressive
behavior, strikes out physically and verbally
when hurt, low frustration level
Has language skills to express pain on a
sensory level; Can identify location and
intensity of pain, denies pain, may believe
his or her pain is obvious to others
School-Age Children
7–9 years (concrete
operations)
Doesn’t understand cause of pain; Understands simple
relationships between pain and disease and need for painful
procedures to treat disease ; May associate pain with feeling bad
or angry; recognize psychologic pain related to grief and hurt
feelings
Passive resistance, clenches fists, holds body
rigidly still, suffers emotional withdrawal,
engages in plea bargaining
Can specify location and intensity of pain
and describes pain physical characteristics
in relation to body parts
10–12 years
(transitional)
Better understanding of relationship between an event and pain;
More complex awareness of physical and psychologic pain,(moral
dilemmas , mental pain)
May pretend comfort to project bravery, may
regress with stress and anxiety
Able to describe intensity and location with
more characteristics, able to describe
psychologic pain
Adolescents
13–18 years
(formal
operations)
Has a capacity for sophisticated and complex under-standing of
causes of physical and mental pain; Recognizes pain has qualitative
and quantitative characteristics; Can relate to pain experienced by
others
Want to behave in socially acceptable manner
-like adults; controlled response; May not
complain if given cues from other healthcare
providers
More sophisticated descriptions with
experience; may think nurses are in tune
with their thoughts, so don’t need to tell
nurse about their pain
Step 3: Family Dynamic Checkpoint
• Who is with the patient?- family, caregiver, etc.
• Who is the legal guardian?
• Who actually cares for the patient?
• Who do you want at the bedside?
• Consider culture, past experiences, time
commitments, family personality, and family stress
level
Step 3. Family Dynamic Checkpoint
Step 4: Facility (Agency/Community) Checkpoint
• Staffing and setting
• Community, rural, children’s hospital
• Provider experience, team capabilities and
expertise
• Existing hospital/agency pain or procedural
sedation policies
• Acuity and overcrowding of the ED, hospital or
clinic
• Other priorities- MCI, natural disaster, etc.
• Equipment, monitoring, backup
Step 4. Facility Checkpoint
Step 5: Patient Assessment Checkpoint
• Review history, assessment and risk factors
• Chronic illness-previous painful experiences, recent
surgery
• Psychiatric and mental considerations
• Injury severity, +/- contraindications to opioids or
sedation
• Body habitus
• Weight- ideal or real? Obesity?
Step 5. Patient Assessment Checkpoint
Step 6: Management Checkpoint:
Choose Your “Recipe”
• No magic recipe, must individualize and adjust “Ingredients”
• Pharmacologic “ingredients”
• Route: oral, nasal, IV, nebulized, topical, nerve blocks
• Type: sucrose, NSAID, opioids, anxiolytics, ketamine
• Nonpharmacologic “ingredients”
• Everyone needs a little child life 101- distraction, music, virtual reality, etc.
• Engage caregivers and parents- coaching, therapeutic language
Always consider nonpharmacologic options +/- medications:
Will pain duration be short (removal of FB, laceration repair), prolonged (burn) or
chronic (rheumatologic)?
Step 6. Management Checkpoint
Step 7: Monitoring And Discharge
Checkpoint
• Joint Commission standards
• Document reassessments
• Patient should be back to baseline and tolerating fluids at discharge
• Consider falls prevention and transportation- especially for patients on opioids or
sedating medications
• Discharge planning and instructions
• Pain plan
Step 7. Monitoring & Discharge Checkpoint
90
Pharmacologic and
Nonpharmacolgoic Management
PAMI Pain Management and Dosing Guide
• The PAMI Pain Management and Dosing
Guide is a free tool for use by health care
providers in all settings and should be used as
general guide when managing pain in pediatric
and adult populations.
• The guide provides treatment options for
opioids, non-opioids, procedural sedation,
nerve blocks, and IV/IM/IN/topical
administration. It includes patient safety
considerations as well as nonpharmacologic
interventions. To take a tour of the dosing
guide, click here!
• A free downloadable pdf of the dosing guide
can be accessed on the PAMI website.
http://pami.emergency.med.jax.ufl.e
du/resources/dosing-guide/
92
Opioid Prescribing and Equianalgesic Chart
Generic (Brand) Onset (O) and Duration (D) Approximate
Equianalgesic Dose
Recommended STARTING
dose for ADULTS
Recommended STARTING
dose for CHILDREN (> 6 mo)
Oral IV Oral IV Oral IV Oral IV
Morphine (MSIR®) [CII] O: 30-60 min
D: 3-6 h
O: 5-10 min
D: 3-6 h
30 mg 10 mg 15-30 mg q
2-4 h
2-10 mg q
2-4 h
0.3 mg/kg q 4
h
0.1 mg/kg
q 2-4 h
Morphine extended release (MS
Contin®) [CII]
O: 30-90 min
D: 8-12 h
— 30 mg 10 mg 15-30 mg q
12 h
— 0.3-0.6 mg/kg q
12 h
—
Hydromorphone (Dilaudid®) [CII] O: 15-30 min
D: 4-6 h
O: 15 min D:
4-6 h
7.5 mg 1.5 mg 2-4 mg q 4
h
0.5-2 mg q
2-4 h
0.06 mg/kg q 4
h
0.015 mg/kg
q 4 h
Hydrocodone/APAP 325 mg
(Norco 5, 7.5, 10®) [CII]
Hycet (7.5 mg/325 mg per 15 mL)
O: 30-60 min
D: 4-6 h — 30 mg —
5-10 mg q
6 h —
0.1-0.2 mg/kg q
4-6 h —
Fentanyl [CII]
(Sublimaze® Duragesic®)
Patch for opioid tolerant patients
ONLY
Transdermal
O: 12-24 h
D: 72 h per
patch
O: immediate
D: 30-60 min
—
100 mcg
(0.1 mg)
Transdermal
12-25 mcg/h
q 72 h
50 mcg q
1-2 h
Transdermal
12-25 mcg/h q
72 h
1-2 mcg/kg
q 1-2 h
(max 50
mcg/dose)
Non-Opioid Analgesics
Generic (Brand) Adult Pediatric (<12 yo)
Acetaminophen
(Tylenol®)
325-650 mg
PO q 4-6 h
Max: 4 g/d or 1 g q 4 h
15 mg/kg
PO q 4-6 h
Max: 90 mg/kg/d
Acetaminophen
IV (Ofirmev®)
Use only if not tolerating
PO
1 g IV q 6 h Max: 4 g/d or 650
mg q 4 h prn pain
<50 kg
15 mg/kg IV q 6 h or 12.5 mg/kg
IV q 4 h prn pain
Max: 75mg/kg/d
Celecoxib (Celebrex®) 100-200 mg
PO daily to q 12 h
Max: 400 mg/d
>2 yo
50 mg PO BID
Ibuprofen (Motrin®)
400-800 mg PO q 6 to 8 h
Max: 3200 mg/d
10 mg/kg
PO q 6 to 8 h
Max: 40 mg/kg/d or 2400 mg/d
Ketorolac (Toradol®)
15-30 mg IV/IM q 6 h
Max: 120 mg/d x 5 d
0.5-1 mg/kg/ dose IM/IV q 6 h
Max: 15-30 mg q 6 h x 5 d
Naproxen (Naprosyn®) 250-500 mg PO q 8 to 12 h
Max: 1500 mg/d
5 mg/kg PO q 12 h
Max: 1000 mg/d
Intranasal* and Nebulized Medications
Generic Dose Max Dose Comments
Fentanyl IN: 1.5-2 mcg/kg q 1-2 h
Neb: 1.7-3 mcg/kg
3 mcg/kg or 100 mcg Divide dose equally
between each nostril
Midazolam
(5 mg/mL)
IN: 0.3 mg/kg 10 mg or 1 mL per
nostril (total 2 mL)
Divide dose equally
between each nostril
Ketamine See Ketamine table
Lidocaine Neb: 4% (40 mg/mL)
100-200 mg or 2.5-5 mL
4.5 mg/kg total or 300
mg
>5 mg/kg associated with
serious toxicity
Ketamine (Ketalar®) Indications and Dosing
Indications Starting Dose
Procedural Sedation IV: Adult 0.5-1.0 mg/kg; Ped 1-2mg/kg;
IM: 4- 5 mg/kg
Sub-dissociative Analgesia^ IV: 0.1 to 0.3 mg/kg;
IM: 0.5-1.0 mg/kg; *IN: 0.5-1.0 mg/kg
Excited Delirium Syndrome IV: 1 mg/kg; IM: 4- 5 mg/kg
Intranasal Medications
• Use concentrated solution
• Ketamine 50 mg/ml*
• Fentanyl 50 mcg/ml*
• Midazolam 5mg/ml
• Use an atomizer
• If > 1ml divide between nares
• Aim spray toward turbinates/pinna
*Rapid CSF levels
96
Ketamine Pharmacology
• Blockade of N-methyl D-aspartate (NMDA) receptors, peripheral Na+
channels and μ-opioid receptors providing sedation, amnesia, and
analgesia.
• High lipid solubility
• allows rapid crossing of the blood-brain barrier,
• quick onset of action (peak concentration at 1 minute-IV)
• Rapid recovery to baseline
97
61
Consensus Guidelines on the Use of Intravenous
Ketamine Infusions for Acute Pain Management
• From the American Society of Regional Anesthesia and Pain Medicine,
the American Academy of Pain Medicine, and the American Society of
Anesthesiologists (Reg Anesth Pain Med 2018;43: 456–466)
• Evidence supports the use of subanesthetic ketamine for acute pain in
a variety of contexts, including as a stand-alone treatment, as an
adjunct to opioids, and, to a lesser extent, as an intranasal
formulation.
New Emphasis on Nonpharmacologic
Methods of Treating Pain
• Nonpharmacologic pain management techniques should be
considered along with pharmacologic techniques and may:
• improve assessment
• decrease or avoid the use of opioids or anxiolytics
• decrease time and recovery for procedures
• decrease adverse events
New Emphasis on Nonpharmacologic
Methods of Treating Pain
Painting Analogy
Think of nonpharmacologic management as your “base coat” or “primer” before
applying additional coats of analgesic treatment. With the right base coat
foundation, you have a better chance of painting a patient’s symptoms a more
tolerable and long-lasting new color.
(PEM Playbook: http://pemplaybook.org/podcast/pediatric-pain/
The Importance of Incorporating
Nonpharmacologic Methods When Treating Pain
In an effort to encourage multimodal approaches, hospitals are now required to
incorporate nonpharmacologic interventions in pain management plans.
These pain assessment and management requirements are designed to improve the
quality and safety of care provided by Joint Commission-accredited hospitals.
Click on the link to find out more!
https://www.jointcommission.org/assets/1/18/Joint_Commission_
Enhances_Pain_Assessment_and_Management_Requirements_for_
Accredited_Hospitals1.PDF
101
Categorization of Nonpharmacologic Interventions
Physical (Sensory) Interventions
Positioning
Cutaneous stimulation
Nonnutritive sucking, sucrose
Pressure
Hot or cold treatments
Others
Cognitive-Behavioral Interventions
Psychologic preparation, education, information
Distraction (passive or active): Video games, TV,
movies, phone, lighted or interactive toy, virtual
reality
Relaxation techniques (breathing, meditation, etc.)
Music
Guided imagery
Training and coaching
Coping statements: “I can do this”
Adapted from: Murray KK, Hollman GA. Non-pharmacologic interventions in children during medical and surgical procedures. In: Tobias JD, Cravero JP, eds.
Procedural Sedation for Infants, children, and adolescents; Section on Anesthesiology and Pain Medicine. American Academy of Pediatrics ; 2016.
Nonpharmacologic Interventions
• Pain can sometimes be adequately managed using
nonpharmacologic interventions such as ice, splinting, distraction,
etc.
• These management options can be applied singly or as adjuncts
along with pharmacological options.
Click here for more information on
nonpharmacologic management options.
For additional information and resources refer to the website and the
Nonpharmacologic PAMI module.
103
Develop Your Own
Distraction &
Nonpharmacologic Pain
Toolkit
Virtual Reality
Distraction &
Nonpharmacologic
Pain Toolkit
b. Re-assessment of Pain
105
Re-assessment of Pain
• Timely reassessment of pain is essential. One of the most common mistakes
made in pain management is failure of reassessment after an intervention
(pharmacologic or nonpharmacologic).
• Pain level should be reassessed after an intervention, such as medication
administration, and once the intervention has had time to exert its effect.
• The timeframe and frequency for re-assessment will depend on the setting.
 For example, re-assessments will be performed frequently and over a
shorter time course in acute care settings, like the ED, compared to
outpatient settings.
 In the acute care settings, consider reassessing pain level 30 minutes after
IV and 60 minutes after PO administration of a medication.
106
Re-assessment of Pain
• The same scale or scoring system used previously should be used on re-
assessment for consistency.
• All patients do not respond to identical management in the same manner due
to genetic and other factors.
• Appropriate monitoring for respiratory depression should be used especially
when using pain relievers with sedating effects (opioids).
• Pain should always be reassessed at time of discharge or within an appropriate
time interval in the outpatient setting.
The literature suggests that a 33% to 50% decrease in pain intensity is clinically
meaningful from a patient's perspective and represents a reasonable standard of
intervention efficacy for acute and chronic pain.
107
c. Consequences of Unrelieved Pain
108
Consequences of unrelieved acute pain
Psychological Impacts
• The psychological impact of untreated pain can include post-traumatic stress disorder,
anxiety, catastrophizing, and depression.
Chronic pain syndromes
• Chronic pain syndromes can develop as a consequence of untreated acute pain mechanisms
including spinal cord hyper-excitability.
Mortality and Morbidity
• Increased mortality and morbidity can result from unrelieved acute pain. This can occur
through increased oxygen demand, increased metabolic rate, cardiovascular and pulmonary
complications, and impaired immune function.
109
Chronic Pain Syndrome
Chronic pain can affect sleep, mood, activity, and energy level. It has both
physical and psychological affects that can result in a detrimental cycle.
110
6. Discharge Planning and
Transitions of Care
111
Discharge Planning for Patients with Pain
• Appropriate discharge planning should take into account what interventions the patient
has received during the visit and transportation home.
• How will the patient safely arrive home? Consider patient transportation and driving precautions, especially
after receiving a sedating medication
• Are they ambulating at their baseline without assistance?
• Could the treatment or medication still be exerting its effects (i.e. lethargy as a side effect of morphine)?
• An important consideration during discharge planning is whether the patient will be able
to safely take the prescribed medications at home. Also consider if the patient will be
able to obtain the prescribed medications from their pharmacy? (ie cost, supply, etc.).
• Patients should be educated on the proper use of their prescribed medications with clear and easy
to understand instructions: potential side effects, interactions with other prescribed medications
and any adverse effects.
• Has the patient been advised to:
• Not drive while taking their prescribed opioid
• Not combine their medication with alcohol
• Not take more than prescribed especially for acetaminophen containing products
• Store medications safely and dispose of unused tablets properly
112
Pain Management Transitions of Care
Sound management of pain during transitions of care is important
because:
 It reduces return visits
 Expedites return to normal activities and work
 Helps reduce risk of acute pain progressing to chronic pain
Patients often take 4-6 weeks to experience pain reduction after an acute
injury! Yet national guidelines support limiting opioid prescriptions to a
week or less.
113
This is why use of multimodal interventions and timely follow up is important.
7. Patient Safety, Regulatory and
Legal Aspects of Pain Management
117
Institution, Local, State, and Federal
Regulations
Providers must be familiar with regulations regarding pain management at
their institution and at the local, state, and federal levels.
Most states now have PDMPs (prescription drug monitoring programs) and opioid
legislation.
118
8. Case Scenario
Discussion
119
Case Scenario 1 A 54 year-old non-English speaking male is brought to the ED by EMS after
sustaining a motorcycle collision approximately 20 minutes prior to arrival.
He has an obvious deformity to his left femur and multiple areas of “road
rash.” He received no pain medications prior to arrival. His left leg is
splinted. His eyes are closed and he appears to be praying. After physical
exam and x-rays, it is determined that he has a left femur fracture and
profuse areas of abrasions and denuded skin contaminated with dirt and
gravel.
A second patient arrives during your assessment of the first patient.
Patient number 2 is a 23 year-old female that was involved in the same
accident. She was the restrained backseat passenger in a pick-up truck,
reports “pain all over” and is crying hysterically. After a thorough exam she
is determined to have mild musculoskeletal strain and one small contusion
of her forehead.
 What factors account for the different reactions to pain in these two patients?
 What are the potential barriers to adequately assessing their pain?
120
Case Scenario 1 Discussion
• Patients respond to and express their degree of pain differently due
to a number of psychosocial factors. The severity of injury alone does
not always dictate the degree of a patient’s pain.
• In this case, patient 1 objectively has sustained more severe injuries.
However, patient 2 presents with a more intense and dramatic
response to her injury and situation.
• There are many barriers the treatment team faces when assessing
and treating these two patients, including language barriers (patient
1), lack of previous physician-patient relationship, simultaneous
evaluation of potentially critical patients, and lack of knowledge
regarding past pain experiences.
121
Case Scenario 2
A 3 year-old right-handed male presents to his pediatrician’s office with
his caregiver who reports that the child has complained of pain in his
right arm since yesterday. When questioned the child denies pain, but
cries and pulls away when any part of the right upper extremity is
touched. He has no obvious deformity or swelling to either arm.
 How would your approach to pain assessment
in this child differ from that of an adult? From
an adolescent?
122
Case Scenario 2 Discussion
• Pediatric patients require a different pain
assessment approach from adults as they
often cannot adequately communicate their
pain symptoms or the severity.
• There are several resources clinicians can use
in addition to patient report. These include
pediatric pain scales, observation of the
patient’s behavior, and question
• You notice the patient to be playful and
interactive, but not using his right arm.
Although the child is attempting his normal
behaviors (such as playing), he is doing so
through compensation. This is confirmed via
his caregiver stating that he has been
favoring his left arm.
• You hand him two toys and he attempts
to hold both toys using his left hand. As
he is distracted with the toys, you are
able to palpate his entire upper
extremity and determine that his pain is
localized to the elbow.
Through the use of observation, surrogate
history provided by the caregiver, and
distraction you are able to localize the
patient’s pain.
123
Case Scenario 3
• A 53 year-old male with chronic back pain underwent knee
replacement one week ago. He presents to his primary care doctor
complaining of persistent post-op pain. The patient reports his
prescribed opioid is not controlling his pain. His pain has greatly
limited his ability to perform his daily living activities.
 How would you manage this patient’s pain? What important questions
regarding his history should be asked?
124
Case Scenario 3
• This patient suffers with chronic back pain which he treats with a
prescription opioid. It is important to ask the patient how long he has
been receiving prescription opioids and at what dose. Also if he was
prescribed any new medications after his surgery.
• Upon further inquiry, the patient indicates that he has been taking
the same opioid medication at the same dose for three years. It has
always controlled his pain until his knee surgery. He reports that he
was not given any new prescriptions for pain after his surgery. He was
told that he should take ibuprofen as needed for pain.
125
Case Scenario 3
• In this case, the patient is suffering with an increase in his baseline
pain due to his recent surgery. The prescription opioid which had
controlled his pain for years is no longer effective given this increase
in pain. It is important to recognize that patients who have taken the
same prescription opioids for significant period of time may need an
increase in dose. Additionally, this patient would likely benefit from a
multimodal approach utilizing other non-opioid pharmacologic and
nonpharmacologic adjuncts.
126
9. Summary
127
 Pain is complex and multifactorial.
 There are several different classifications of pain depending on location and
etiology.
 Successful management of pain relies on a thorough pain history and exam, a
stepwise approach, timely re-assessments, and appropriate selection of
pharmacological and nonpharmacologic management options.
 There is no test that can adequately identify or measure pain.
 Chronic pain is a potential outcome of untreated acute pain.
 Discharge planning must take into account several safety concerns and should
be centered on patient education.
128
Summary

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Pain Algorithms, Assessment and Management.pdf

  • 1. Basics of Pain Assessment and Management 1
  • 2. Learning Objectives 1. Understand the importance of pain recognition, assessment and re-assessment. 2. Discuss the multi-factorial determinants of pain. 3. Identify the different classifications of pain and how this impacts treatment selection. 4. Discuss the key elements of performing an accurate pain history and examination. 5. Understand the different types of pain scales. 6. Describe the consequences of untreated pain. 7. Recognize patient safety issues regarding pain management, discharge planning, and transitions of care. 5
  • 3. Consider these case scenarios throughout the module A 54 year-old non-English speaking male is brought to the ED by EMS after sustaining a motorcycle collision approximately 20 minutes prior to arrival; he is calm and reports mild pain. Simultaneously, a 23 year-old female that was involved in the same accident is brought to the ED. She was the restrained backseat passenger in a pick-up truck; reports “pain all over” and is crying hysterically. A 3 year-old right-handed male presents with his caregiver who reports that the child has complained of pain in his right arm since yesterday. When questioned the child denies pain but cries and pulls away when any part of the right upper extremity is touched. He has no obvious deformity or swelling to either arm. A 53 year-old male with chronic back pain underwent knee replacement one week ago. He presents to his primary care doctor complaining of persistent post-op pain. The patient reports his prescribed opioid is not controlling his pain The pain is limiting his ability to perform his daily activities of living. 6
  • 4. 1. Introduction to Pain Management 8
  • 5. Why is Pain Management Important? • Pain is a complex and common complaint that leads to frequent access of the US healthcare system. • Chronic pain alone affects more Americans than diabetes, cancer, and heart disease combined, with an estimated annual cost of $600 billion. • Pain is often under recognized leading to inadequate management and numerous patient safety concerns, particularly in special populations and minority groups. • Untreated acute pain may lead to adverse sequelae. • With the recent opioid epidemic and advances in pain research, there is a renewed emphasis on early multimodal pain management, nonpharmacologic options and nonopioid alternatives.
  • 6. General Pain Management Challenges (part 1) • Failure to recognize or differentiate pain from anxiety • Lack of education for healthcare providers, especially regarding nonpharmcologic modalities. • Safety concerns, fear of patient addiction or prescription legal repercussions • Lack of pre-existing physician-patient relationships i.e. knowledge of past medical history • Inadequate discharge pain plans resulting in return visits or admissions • Pressure to see patients rapidly, especially those perceived to be more critical, which can hinder time for adequate pain assessments and re-assessments 10
  • 7. General Pain Management Challenges (part 2) • Physiologically unstable patients are least likely to receive a standardized pain assessment and to receive pain medications • Outpatient settings may have limited time to perform full pain assessments or to evaluate for psychosocial contributors to pain (e.g. financial stress, impaired sleep, anxiety, etc.) • Stereotypes towards patients with chronic pain being drug- seekers • Analgesic shortages leading to medication errors and changing protocols • And many more! 11
  • 8. Challenges Summary- Keeping Balance • Healthcare providers face the dilemma of balancing safe opioid/analgesic prescribing and high-risk patient recognition with appropriate pain management strategies for those in significant pain while being mindful of different types of pain, individual pain factors and comorbidities.
  • 9. Cognitive Functioning Genetics Religion Clinical How Does Pain Affect Us? • Pain is multidimensional, affecting people physically, psychologically, socially and spiritually. • Patients’ responses to pain may be related to: • genetics, age, gender, ethnicity, socioeconomic and psychiatric factors, catastrophizing, culture, religion, previous experiences, patient perceptions and expectations, etc. 14 Pain Demographics Cognitive Functioning Genetics Culture Psycho- social Religion Clinical
  • 10. • A patient’s response to prescribed pain treatment can be influenced by factors unrelated to actual pharmacological treatments. These factors include: – Perceived effective communication with physicians and nurses by the patient – Perceived responsiveness by the treating team – Perceived empathy by the treating team Patient Perceptions 15
  • 11. Factors Affecting Patient Response To Painful Stimuli • Age, Gender, Ethnicity • Socioeconomic and Psychological factors • Catastrophizing • Culture and Religion • Genetics • Previous experiences • Patient perceptions • Patient expectations 16
  • 12. Patient Response to Pain and Management: Age and Gender • Demographics such as age, gender, race and ethnicity have all been reported to influence pain perception. • Studies on the influences of gender and age have had variable results. • Overall, patients who identify as female display more sensitivity than males towards most painful conditions. Females also are believed to express their pain more frequently and effectively than males. • Studies have shown different interpretations by observers for the same facial expressions depending on patient gender. • This behavior could explain why patients are managed differently by providers when presenting with the same injury or painful condition. 17
  • 13. Patient Response to Pain and Management: Ethnicity • Ethnicity is associated with pain intensity and interference. – One study found African Americans to report higher rates of pain and interference with daily activities such as sleep. Consider the impact of age, gender and ethnicity on pain assessment and management but beware of labeling or stereotyping- treat the individual patient! 18
  • 14. Patient Response to Pain and Management: Culture and Religion • Culture and Religion/Personal Values/Coping Mechanisms – How patients cope with pain can be influenced by their existing social support system. – Those with strong cultural and religious ties tend to have stronger support mechanisms for dealing with their pain. – Variations in cultural norms can influence how a patient expresses their pain and how they want their pain to be managed. 19
  • 15. Patient Response to Pain and Management: Socioeconomic and Psychological Factors • Health disparities research indicates that patients living in rural areas and who are of lower socioeconomic status tend to report higher levels of chronic pain, pain related disability, and depression. Depression and pain often co-exist (30-60% of pain patients also report depression). • Previous pain experiences can alter activity within certain brain regions responsible for pain processing resulting in persistent pain. • Additionally, mood disorders and other psychiatric disorders have been linked to the development of chronic pain. This co-existence has important clinical and financial implications. These patients often report more pain, greater functional disability, worse clinical prognosis, and accrue higher healthcare costs. 20
  • 16. Patient Response to Pain and Management: Pain Catastrophizing • Pain catastrophizing is an exaggerative cognitive response to an anticipated or actual painful stimulus and affects how individuals experience and express pain. • People who catastrophize tend to magnify their pain, ruminate about their pain, and feel helpless in managing their pain. • Pain catastrophizing shares similarities with depression and anxiety. It has been associated with pain-related outcomes such as pain severity, activity interference and disability, depression, changes in social support networks, more frequent healthcare visits, and opioid usage. 21
  • 17. Examples Of Catastrophizing • Magnification: the response that symptoms that can be or are greater than expected. Ex: “I´m afraid that something serious might happen” • Rumination: when an individual focuses repeatedly on attributes of an event that evoke a negative emotional response. Ex: "I can´t stop thinking about how much it hurts“ • Helplessness: the belief that there is nothing that anyone can do to improve a bad situation. Ex: "There is nothing I can do to reduce the intensity of my pain". 22
  • 18. • Genetic polymorphisms play an integral role in how patients respond to painful stimuli and treatment. • For example, populations within certain ethnic groups are known to carry genetic mutations of the liver CYP450 enzymes responsible for drug metabolism. • Some patients are “ultra-rapid metabolizers” of certain drugs such as codeine. This means they convert codeine to morphine more rapidly than other patients, resulting in potential supra-therapeutic dosing. • Some patients are “slow metabolizers” and do not efficiently metabolize codeine, and thus never achieve therapeutic levels. • Caucasian and African American populations have approximately equal proportions of fast and slow metabolizers, whereas nearly 90% of certain Asian groups are fast acetylators. 23 Patient Response to Pain: Genetics
  • 20. Classification of Pain • Determining the context, history of present illness and type of pain is complex and time consuming but is essential to developing a successful management plan. • Pain may be classified by underlying etiology, anatomic location, temporal nature, and intensity. • Underlying etiology refers to the source of the experienced pain. • Anatomic location refers to the site of pain within the body • Temporal nature refers to the duration of the pain. • Intensity refers to the degree or level of the pain experience . 25
  • 22. • Nociceptive Pain is the result of direct tissue injury from a noxious stimulus. Nociceptive pain can be further classified as somatic or visceral pain. • Examples include bone fracture, new surgical incision, and acute burn injury. • Inflammatory Pain is the result of released inflammatory mediators that control nociceptive input and are released at sites of tissue inflammation. • Examples include appendicitis, rheumatoid arthritis, inflammatory bowel disease, and late stage burn healing. • Neuropathic Pain is the result of injury to nerves leading to an alteration in sensory transmission. It can be central or peripheral in nature. • Examples include diabetic peripheral neuropathic pain, postherpetic neuralgia, chemotherapy induced pain, and radiculopathy. Underlying Etiology Nociceptive Inflammatory Neuropathic 27
  • 23. • Somatic Pain, also known as musculoskeletal pain, is pain that occurs from injury to skin, muscle, bone, joint, connective tissue and deep tissues. Typically pain is well-localized, sharp and worse with movement. • Examples include lacerations, fractures, and pelvic pain. • Visceral Pain is internal pain and typically occurs from internal organs or tissues that support them. Pain is usually poorly localized and described as vague deep aches, colicky, and/or cramping. • Examples include appendicitis, peptic ulcer disease, diverticulitis, endometriosis, and ureteral stones. 28
  • 24. • Acute pain is defined as lasting less than 3 months and is a neurophysiological response to noxious injury that should resolve with normal healing. • Examples include post-operative pain, fractured bones, appendicitis, crush injury to finger, labor and delivery pain. • Chronic pain is defined as lasting more than 3 months or beyond the expected course of an acute disease or after complete tissue healing. Chronic pain extends beyond the time of normal wound healing with the development of multiple neurophysiological changes in the central nervous system. • Examples include low back pain, neck pain, and chronic pancreatitis. • Acute on Chronic pain refers to times of acute exacerbations of a chronic painful syndrome or new acute pain in a person suffering from a chronic condition. • Examples include a sickle cell exacerbation in a patient with sickle cell disease or an abscess in a patient with sickle cell disease. 29
  • 25. Pain intensity can range from: Scores typically range from: Mild 1-4 Moderate 5-7 Severe 8-10 Pain Intensity is determined by pain assessment scores in combination with history and physical exam. Pain intensity is subjective and may vary from one patient to another. Pain Scales are used to assess and quantify the intensity of a patients pain. Remember that each scale has its’ own scoring range and levels for mild, moderate or severe pain intensity. • Case scenario 1 is an example of the challenges involved in determining intensity where one patient has severe injuries but rates their pain as moderate compared to the patient with minor injuries who complains of severe “pain all over.” 30
  • 26. TYPES OF PAIN MECHANISM CINICAL EXAMPLES PHARMACOLOGICAL TREATMENT OPTIONS* UNDERLYING ETIOLOGY Nociceptive The result of direct tissue injury from a noxious stimuli. Bone fracture, fresh surgical incision, and fresh burn injury. May include both opiate and non-opiate medications depending on injury. Inflammatory The result of released inflammatory mediators that control nociceptive input. Late stages of burn healing, neuritis, and arthritis Anti-inflammatory agents Neuropathic The result of direct injury to nerves leading to an alteration in sensory transmission. Diabetic neuropathy, peripheral neuropathic pain, and post-herpetic neuralgia. Tricyclic, selective norepinephrine reuptake inhibitors, gabapentinoids, or antidepressants Idiopathic Unknown Chronic back pain without preceding trauma or obvious inciting event. May be difficult to adequately address pain since underlying etiology is unknown, especially in emergency settings. ANATOMIC LOCATION Somatic A-delta-fiber activity located in peripheral tissues Superficial lacerations, superficial burns, superficial abscess Topical and/or local anesthetics, opiates, non-opiates Visceral C fiber activity located in deeper tissues such as organs Uterine fibroid pain, pyelonephritis, biliary colic Opiates TEMPORAL NATURE Acute A neurophysiological response to noxious injury that should resolve with normal wound healing. Acute fracture, acute knee sprain Opiate, non-opiates Chronic Pain that extends beyond the time for normal wound healing with resultant development of multiple neurophysiological changes Chronic low back pain, fibromyalgia, arthritis Depends on the nature of the pain. Please refer to the module on chronic pain for more detailed information. Acute-on-chronic An acute exacerbation of a chronic pain syndrome Sickle cell disease, cancer, rheumatoid arthritis, acute injury in chronic pain patient *Nonpharmacologic management options should be considered at any time for any type of pain Table 1. Types of pain, mechanism, and clinical examples For more information on Nonpharmacologic Pain Management, please refer to the pdf or learning module 31
  • 27. 3. How to Perform a Pain Assessment a. Components of the Pain History b. Pain Focused Physical Exam 32
  • 28. a. Components of the Pain History 33
  • 29. Pain History Elements and Questions Basics 1. Onset of recent pain 2. Aggravating and alleviating factors 3. Quality of pain experience 4. Location of pain 5. Severity of pain 6. Circumstances of original pain The patient’s history and physical exam can be an invaluable source when it comes to determining the proper diagnosis and course of treatment. Essential elements should include a detailed history of the current pain and, for those that suffer from chronic pain, their previous pain history. Functionality 1. How is pain affecting current level of function? 2. Is patient working? 3. How is patient coping with pain? 34
  • 30. Pain History Elements and Questions Psychosocial and psychiatric 1. Depression 2. Suicidal ideation or past suicide attempts 3. Past psychiatric admissions 4. Physical, sexual and/or emotional abuse. Co-morbidities 1. Significant past medical and/or surgical history 2. Chronic diseases (obesity, hypertension, diabetes, etc. ) 3. Psychosocial and/or psychiatric co- morbidities 4. Family history of substance abuse Consider using the mnemonics OPQRST, SOCRATES and QISS TAPED to assess pain. 35
  • 31. Pain History Elements and Questions Essential elements of Pain History – Basics Basic Elements Description 1. Onset of recent pain • When did the pain start and what was the patient doing when it started • Was the onset sudden, gradual, or an exacerbation of a chronic problem 2. Aggravating and alleviating factors • What makes the pain better and what makes it worse? • How does physical activity or position affect pain? • Do any nonpharmacological therapies or medications relieve the pain? 3. Quality of pain experience • Ask the patient “Can you describe the pain?” Ideally, this will elicit descriptions of the patient's pain: whether it is sharp, dull, crushing, burning, tearing, or some other feeling, along with the pattern, such as intermittent, constant, or throbbing. 4. Location of pain • Where pain is on the body and whether it radiates (extends) or moves to any other area? 5. Severity of pain • Ask the patient to describe the intensity of pain at baseline and during acute exacerbations, typically done using a pain scale 6. Circumstances of original pain • Identify when the pain started, under what circumstances, duration, onset (sudden/gradual), frequency, whether acute/chronic. 36
  • 32. Consider using a patient pain diagram at check-in or triage (if stable) 37
  • 33. Pain History Elements and Questions Mnemonics for obtaining pain history OPQRST • Site • Onset • Character • Radiation • Associations • Time course • Exacerbating/Reli eving factors • Severity SOCRATES • Onset of event • Provocation and palliation of symptoms • Quality • Region and radiation • Severity • Timing • Quality • Impact • Site • Severity • Temporal • Aggravating and alleviating • Past response and preferences • Expectations and goals • Diagnostics and physical exam QISS TAPED 38
  • 34. OPQRST O Onset of event • What was the patient doing when it started? Were they active, inactive, and or stressed? • Did that specific activity prompt or start the onset of pain? • Was onset of pain sudden, gradual or part of an ongoing chronic problem P Provocation and palliation of symptoms • Is the pain better or worse with: • Activity. Does walking, standing, lifting, twisting, reading, etc… have any effect of the pain? • Position. Which position causes or relieves pain? Provide examples to the patient-- sitting, standing, supine, lateral, etc… • Adjuvant. Which type of medication relieves the pain (Tylenol, Ibuprofen, etc.. )? Does the use of heat or ice packs alleviate pain? What type of alternative therapy (massage, acupuncture) have you used before? • Does any movement, pressure (such as palpation) or other external factor make the problem better or worse? This can also include whether the symptoms relieve with rest. Q Quality • Ask the patient to describe the quality of pain – is it throbbing, dull, aching, burning, sharp, crushing, shooting, etc…? • Questions can be open ended "Can you describe it for me?" or leading • Ideally, this will elicit descriptions of the patient's pain: whether it is sharp, dull, crushing, burning, tearing, or some other feeling, along with the pattern, such as intermittent, constant, or throbbing. 39
  • 35. OPQRST R Region and radiation • Where pain is on the body and whether it radiates (extends) or moves to any other area? Referred pain can provide clues to underlying medical causes. • Location: body diagrams may help patients illustrate the distribution of their pain. • Dermatome map – may help determine the relationship between sensory location of pain and spinal nerve segment (see figure next slide). • Referred vs Localized: referred pain (also known as reflective pain) is feeling pain in a location other than the original site of the painful stimulus. Localized pain is when pain typically stays in one location and does not spread. S Severity • Ask the patient to describe the intensity of pain at baseline and during acute exacerbations. • The pain score (usually on a scale of 0 to 10) where 0 is no pain and 10 is the worst possible pain. This can be comparative (such as "... compared to the worst pain you have ever experienced") or imaginative ("... compared to having your arm ripped off by a bear"). If the pain is compared to a prior event, the nature of that event may be a follow-up question. T Timing • Identify when the pain started, under what circumstances, duration, onset (sudden/gradual), frequency, whether acute/chronic. • How long the condition has been going on and how it has changed since onset (better, worse, different symptoms)? • Whether it has ever happened before, and how it may have changed since onset, and when the pain stopped if it is no longer currently being felt? 40
  • 36. S Site Where is the pain? Or the maximal site of the pain. O Onset When did the pain start, and was it sudden or gradual? Include also whether if it is progressive or regressive. C Character What is the pain like? An ache? Stabbing? R Radiation Does the pain radiate anywhere? (See also Radiation.) A Associations Any other signs or symptoms associated with the pain? T Time course Does the pain follow any pattern? E Exacerbating/Relieving factors Does anything change the pain? S Severity How bad is the pain? SOCRATES 41
  • 37. QISS TAPED Q Quality What were your first symptoms? What words would you use to describe the pain? (achy, sharp, burning, squeezing, dull, icy, etc...) Besides sensations you consider to be "pain," are there other unusual sensations, such as numbness? I Impact How does the pain affect you? How does the pain impact your sleep, activity, mood, appetite (other - work, relationships, exercise, etc.) What does the pain prevent you from doing? (Depression screen) Do you feel sad or blue? Do you cry often? Is there loss of interest in life? Decreased or increased appetite? (Anxiety screen) Do you feel stressed or nervous? Have you been particularly anxious about anything? Do you startle easily? S Site Show me where you feel the pain. Can you put your finger/hand on it? Or show me on a body map? Does the pain move/radiate anywhere? Has the location changed over time? S Severity On a 0-10 scale with 0 = no pain and 10 = the worst pain imaginable, how much pain are you in right now? What is the least pain you have had in the past (24 hours, one week, month)? What is the worst pain you have had in the past (24 hours, one week, month)? How often are you in severe pain? (hours in a day, days a week you have pain)? 42
  • 38. QISS TAPED T Temporal Characteristics When did the pain start? Was it sudden? Gradual? Was there a clear triggering event? Is the pain constant or intermittent? Does it come spontaneously or is it provoked? Is there a predictable pattern? (e.g., always worst in the morning or in the evening? Does it suddenly flare up?) A Aggravating and Alleviating Factors What makes the pain better? What makes the pain worse? When do you get the best relief? How much relief do you get? How long does it last? P Past Response, Preferences How have you managed your pain in the past? (Ask about both drug and non-drug methods) What helped? What did not help? (Be specific about drug trials - how much and how long?) What medications have you tried? Was the dose increased until you had pain relief or side effects? How long did you take the drug? Are there any pain medicines that have caused you an allergic or other bad reaction? How do you feel about taking medications? Have you tried physical or occupational therapy? What was done? Was it helpful? Have you tried spinal or other injections for pain treatment? What was done? Was it helpful? E Expectations, Goals, Meaning What do you think is causing the pain? How may we help you? What do you think we should do to treat your pain? What do you hope the treatment will accomplish? What do you want to do that the pain keeps you from doing? What are you most afraid of? (Uncovers specific fears, such as fear of cancer, which should be acknowledged and addressed.) D Diagnostics & Physical Exam Examine and inspect site, Perform a systems assessment and examination as indicated Review imaging, laboratory and/or other test results as indicated 43
  • 39. Pain History Elements and Questions Medical and Surgical History Medical or surgical issues related to patient’s pain or treatment may include: Cancer • Different types of pain may be caused by multiple etiologies: • Tumors: involvement of bone, vessels, nerves, body organs • Diagnostic procedures: may be painful such as biopsies, lumbar punctures, or venipuncture • Treatment: radiation, chemotherapy, or surgical excision Recent Surgery • Incisional pain • Complications such as anastomotic leak, bleeding, compartment syndrome, etc.. Other Conditions • Diabetes which can lead to neuropathic pain • Herpes zoster which can lead to radicular pain • Migraines which can lead to mixed etiology 44
  • 40. Patient Factors to Consider When Assessing Pain Assessing pain in certain special populations can be challenging and requires multiple considerations such as: • Age • Level of development • Communication skills/language • Cognitive skills • Prior pain experiences • Associated beliefs 45
  • 41. Medical and Pain Communication Cards Download and print your own set here Medical Communication Cards or scan the QR code Communication cards are used to assist healthcare providers in communicating with scared, nonverbal or non-English speaking patients and families! • History taking and assessment • Pain, mechanism of injury • Explanation of treatments • Procedures and testing • Discharge instructions 46
  • 42. b. Pain Focused Physical Exam 47
  • 43. During initial pain assessment, physical examination of the patient should be conducted. Pain Assessment: Physical Examination You should be examining the patient’s: Examples Appearance obese, emaciated, histrionic, flat affect Posture splinting, scoliosis, kyphosis Gait antalgic, hemiparetic, using assisting devices Facial Expression grimacing, tense, diaphoretic, anxious Vital Signs sympathetic overactivity, temperature asymmetries 48
  • 44. Pain Assessment: Physical Examination You should be examining the Painful Area(s): Example Inspection • Skin: color changes, hair loss, flushing, goose bumps, sweating • Muscle: atrophy or spasm • Edema Palpation • Demarcation of the painful area • Detection of changes in pain intensity within the area • Trigger points • Changes in sensory or pain processing Musculoskeletal system • Flaccidity: extreme weakness (may be from paralysis) • Abnormal movements: neurologic damage or impaired sense of proprioception, reduced sense of light touch • Limit range of motion: disc disease, arthritis, pain Neurological exam • Cranial nerve exam • Motor strength • Spinal nerve function: deep tendon reflexes, pinprick, proprioception • Coordination: Romberg’s test, toe-to-heal, finger-to-nose, rapid hand movement 49
  • 45. Pain Assessment: Physical Examination 1. Note the patient’s vital signs as they can provide a clue to pain severity • An elevation in blood pressure and heart rate can occur secondary to pain and inadequate control of pain. • However, normal vital signs should not negate a patient’s reported pain. Always review vital signs. 50
  • 46. 2. Take cues from your patient • Patients will often assume a position of comfort. • Observe vocalizations (crying child), facial expressions, body posture, movements, and motor response (decreased movement). • Observe physiological clues such as skin flushing, diaphoresis, and/or vital sign abnormalities. • Consider the patient’s baseline mental status. Are they able to effectively communicate their pain to you? • Perform a focused exam taking into account the information given by the patient. The exam should also assess the patient’s functionality. • A sensory exam should always be conducted in patients with pain especially neuropathic pain. Pain Assessment: Physical Examination 51
  • 47. 4. Pain Assessment Scales a. Adult Pain Assessment Scales b. Pediatric Pain Assessment Scales 52
  • 48. Pain Assessment Scales As a healthcare provider, it is essential to know and understand which pain assessment tools and scales are used in your institution. • Pain scales are typically applied to all pain types. However, chronic and cancer-related pain may require more complex evaluation tools. • Although pain is multi-factorial, the majority of pain scales assess pain intensity. • There are different validated pain scales available for a variety of patient populations such as:  adults  pediatrics  elderly  non-verbal • Not all pain scales are equal and one should be chosen based on the patient. • For example, it would be inappropriate to use a pain scale intended for adults, such as the Defense and Veterans Pain Rating Scale 2.0, when assessing a three-year-old child. 53
  • 49. Pain Assessment Using Pain Scales • Once a pain scale is chosen, interpretation of the score is not so straightforward. • There is no defined score or threshold for what score correlates to actual pain and to what intensity the pain is felt by the patient. • Using the same scale for two different patients doesn’t allow for comparison of pain intensity. For example, a patient with a score of 9 on the Numerical Rating Scale may not necessarily be experiencing more pain than one with a score of 6 on the same scale. • Because of the subjective nature of standardized pain scales, patient functionality may be the best indicator of pain intensity. • Pain scales DO NOT take into account patient genetics, past experiences, comorbidities, or other pain influencing factors. • In patients with preexisting pain it is important to determine their baseline pain level. Select a scale and be consistent! 54
  • 50. Pain Assessment Using Pain Scales • When using a pain scale in a verbal adult it is best to ground the scale by providing context for the patient. • For example, ask the patient at which level on the pain scale would they take an over-the- counter pain medication? For those with chronic pain, what level of pain do they experience every day? • Surrogate reporting (pain history obtained from a parent, caregiver or loved one) of a non-verbal patient’s pain and behavior or activity changes can also aid in pain assessment. • Try to determine who really provides the patient’s daily care and is knowledgeable about their history, disease, and past pain management or experiences. Don’t forget that abnormal vital signs or a change in vital signs can also serve as an indirect marker for pain. 55
  • 51. Pain Scales* Verbal, Alert and Oriented Non-verbal, GCS <15 or Cognitive Impairment Adult 1. Verbal Numeric Scale (VNS)/ Numeric Rating Scale (NRS) 2. Visual Analogue Scale (VAS) 3. Defense and Veterans Pain Rating Scale (DVPRS 2.0) 1. Adult Non-Verbal Pain Scale (NVPS) 2. Assessment of Discomfort in Dementia (ADD) 3. Behavioral Pain Scale (BPS) 4. Critical-Care Observation Tool (CPOT) Pediatric 3 yo and older 1. Wong Baker Faces 2. Oucher (3-12yrs) 3. Numerical Rating Scale (NRS) (7-11yrs) 8 yo and older 1. Visual Analogue Scale (VAS) 2. Verbal Numeric Scale (VNS)/ Numeric Rating Scale (NRS) Birth – 6 mos 1. Neonatal Infant Pain Scale (NIPS) 2. Neonatal Pain Assessment and Sedation Scale (N-PASS) 3. Neonatal Facial Coding System (NFCS) 4. CRIES Infant and older 1. Revised Faces, Legs, Activity, Cry, and Consolability (r-FLACC) 2. Non Communicating Children’s Pain Checklist (NCCPC-R) 3. Children’s Hospital of Eastern Ontario Pain Scale (CHEOPS) (ages 1-7) Examples of Pain Scales 56 *This is a short list of pain scales. Determine which pain assessment tools are used by your agency or facility. To learn more about the different scales, visit PAMI 56
  • 52. a. Adult Pain Assessment Scales 57
  • 53. Adult Pain Scales: Verbal, alert and oriented Measurement Scale Description Verbal Numeric Scale (VNS)/ Numeric Rating Scale (NRS) Self-report scale. Eleven point scale that requires understanding of numbers, addition and subtraction. Verbal rating scale (VRS) Five pain levels are indicated in large print on a sheet give to the patient: no, pain, mild pain, moderate pain, severe pain, unbearable pain. Visual Analogue Scale A 100-mm rule with a movable cursor: “no pain” is written at he left end of the horizontal line along which the cursor is moved, and “maximal pain” at the right end. Defense and Veterans Pain Rating Scale 2.0 (DVPRS) Self-report scale. Eleven point scale that requires the patient to identify pain by numerical rating, color intensity, facial expression, and pain disruption. Followed by four supplemental questions evaluating the biopsychosocial impact of pain. 58
  • 54. Verbal Numeric Scale (VNS) Numeric Rating Scale (NRS) 59
  • 55. Defense and Veterans Pain Rating Scale 2.0 (DVPRS) 60
  • 56. Measurement Scale Description Adult Non-Verbal Pain Scale (NVPS) Behavioral scale. Based on FLACC scale and contain behavioral dimensions and physiology dimensions that are graded by severity. Pain Assessment in Advanced Dementia (PAINAD) Scale Assesses pain in patients with dementia. Total scores range from 0 to 10 (based on a scale of 0 to 2 for five items: breathing. Vocalization, facial expression, body language, and consolability), higher score indicates more severe pain Behavioral Pain Scale (BPS) Behavioral scale. Three observational items (facial expression, upper limbs, and compliance with ventilation). Higher score, greater discomfort. Critical-Care Observation Tool (CPOT) Behavioral scale. Used for intubated and nonintubated critical care patients. Four domains (facial expressions, movements, muscle tension, and ventilator compliance. Higher score, great pain level Adult Pain Scales: Non-verbal, GCS <15 or Cognitive Impairment 61
  • 57. Adult Non-Verbal Pain Scale (NVPS) 62
  • 58. Pain Assessment in Advanced Dementia (PAINAD) Scale 63
  • 59. Behavioral Pain Scale (BPS) Payen JF, Bru O, Bosson JL, Lagrasta A, Novel E, et al. Assessing pain in critically ill sedated patients by using a behavioral pain scale. Crit Care Med. 2001; 29:2258-2263. 64
  • 61. b. Pediatric Pain Assessment Scales 66
  • 62. Pediatric Pain Scale Descriptions Measurement Scale Age Range Description Birth - 6 months Neonatal Infant Pain Scale (NIPS) Preterm and full term neonates Behavioral scale. Neonatal Pain Assessment and Sedation Scale (N-PASS) Preterm and full term neonates Behavioral and physiologic scale. Neonatal Facial Coding System (NFCS) 32 weeks gestation to 6months Facial muscle group movement, brow budge, eye squeeze, nasolabial furrow, open lips, stretch mouth lip purse, taut tongue, and chin quiver CRIES 32 weeks gestation to 6 months Behavioral and physiologic scale. Infant and older (non-verbal children) Faces, Legs, Activity, Cry, and Consolability (FLACC) 2 months to 7 years, critically ill, cognitively impaired, and older than three years of age unable to utilize a self-report scale. Behavioral scale. Scored in a range of 0–10 with 0 representing no pain. The scale has five criteria, which are each assigned a score of 0, 1 or 2. Non Communicating Children’s Pain Checklist (NCCPC-R) 3-19 years (with cognitive impairment) 30 items that assess seven dimensions: vocal, eating/sleeping, social, facial, activity, body/limb, and physiologic signs 3 years and older Wong Baker Faces 3 years and older Self-report scale. Please refer to specific references for those alternative face scales. Oucher 3 -12 years Self-report tool consisting of a vertical numerical scale and a photo scale with expressions of “hurt” to “no hurt.” 8 years and older Visual Analogue Scale (VAS) 8 years and older Self-report scale. Consists of pre-measured vertical or horizontal line, where the ends of the line represent extreme limits of pain intensity. Requires understanding of numbers, addition and subtraction. Verbal Numeric Scale (VNS)/ Numeric Rating Scale (NRS) 8 years and older Self-report scale. Eleven point scale that requires understanding of numbers, addition and subtraction. 67
  • 63. Pediatric Pain Scales: Birth to 6 months Measurement Scale Age Range Description Birth - 6 months Neonatal Infant Pain Scale (NIPS) Preterm and full term neonates Behavioral scale. Neonatal Pain Assessment and Sedation Scale (N-PASS) Preterm and full term neonates Behavioral and physiologic scale. Neonatal Facial Coding System (NFCS) 32 weeks gestation to 6months Facial muscle group movement, brow budge, eye squeeze, nasolabial furrow, open lips, stretch mouth lip purse, taut tongue, and chin quiver CRIES 32 weeks gestation to 6 months Behavioral and physiologic scale. 68
  • 64. Neonatal Infant Pain Scale (NIPS) The NIPS (Lawrence et al., 1993) was developed at Children’s Hospital of Eastern Ontario. The NIPS assesses six behavioral indicators in response to painful procedures in preterm newborns (gestational age < 37 weeks) and full-term newborns (gestational age > 37 weeks to 6 weeks after delivery). 69
  • 65. Neonatal Pain Assessment and Sedation Scale (N-PASS) 70
  • 66. Pediatric Pain Scales: Infant and older (nonverbal children) Measurement Scale Age Range Description Infant and older (non-verbal children) Faces, Legs, Activity, Cry, and Consolability (FLACC) 2 months to 3 years, critically ill, cognitively impaired, and older than three years of age unable to utilize a self-report scale. Behavioral scale. A revised FLACC (r-FLACC) was developed for children with cognitive impairment (CI). It contains the same core components as the original FLACC. Non Communicating Children’s Pain Checklist (NCCPC-R) 3-19 years (with cognitive impairment) 30 items that assess seven dimensions: vocal, eating/sleeping, social, facial, activity, body/limb, and physiologic signs Children’s Hospital of Eastern Ontario Pain Scale (CHEOPS) 1-7 years Observational scale for measuring postoperative pain in children. 71
  • 67. Faces, Legs, Activity, Cry, and Consolability (FLACC) 72
  • 68. Children’s Hospital of Eastern Ontario Pain Scale (CHEOPS) 73
  • 69. Pediatric Pain Scales: 3 years and older Measurement Scale Age Range Description 3 years and older Wong Baker Faces 3 years and older Self-report scale. Please refer to specific references for alternative face scales. Oucher 3 -12 years Self-report tool consisting of a vertical numerical scale and a photo scale with expressions of “hurt” to “no hurt.” 74
  • 71. Pediatric Pain Scales: 8 years and older Measurement Scale Age Range Description 8 years and older Visual Analogue Scale (VAS) 8 years and older Self-report scale. Consists of pre-measured vertical or horizontal line, where the ends of the line represent extreme limits of pain intensity. Requires understanding of numbers, addition and subtraction. Verbal Numeric Scale (VNS)/ Numeric Rating Scale (NRS) 8 years and older Self-report scale. Eleven point scale that requires understanding of numbers, addition and subtraction. 76
  • 72. Verbal Numeric Scale (VNS)/ Numeric Rating Scale (NRS) 77
  • 73. 5. Management of Pain a. General principles of pain management b. Re-assessment of pain c. Consequences of Unrelieved Pain 78
  • 74. a. General Principles of Pain Management - Stepwise approach - Pharmacologic management - Nonpharmacologic modalities - Patient safety considerations - Tranisitions of care and discharge planning 79
  • 75. General Principles of Pain Management In this section general principles of pain management will be reviewed. Due to the changing landscape of pain management, specific pharmacological and nonpharmacologic treatments will not be discussed. For more detailed information on specific pain management, therapies and treatments refer to the other PAMI modules, PAMI stepwise approach and the PAMI Pain Management and Dosing Guide. 80
  • 76. Pain Management: Putting it All Together • No Perfect Recipe or “Cookbook” • No Universal Recipe
  • 77. Overview of PAMI Stepwise Approach to Pain (Adapted to Setting- ED, Hospital, EMS) Ideal approach not always possible Step 7. Monitoring & Discharge Checkpoint Step 6. Management Checkpoint Step 2. Developmental or Cognitive Checkpoint Step 3. Family Dynamic Checkpoint Step 1. Situation Checkpoint Step 5. Patient Assessment Checkpoint Step 4. Facility Checkpoint Pain Management brings challenges to healthcare. The choice of tools you use can be determined by using a stepwise approach that is outlined next.
  • 78. Step 1: Determine the Situation: What are you trying to accomplish or manage? • Pain only • Pain and anxiety or agitation • Anxiety only • Agitation only • Procedure that will induce pain or anxiety- transport, IV,……… • Chronic pain condition exacerbation Determination accomplished after triage, history, and exam Step 1. Situation Checkpoint
  • 79. Step 2: Perform a Developmental Checkpoint • What is the developmental stage of patient? • Is development normal for age? • Developmental delay • Autism • Special health care needs • Mental health concerns • Recent traumatic events • Regression to lower developmental stage What are characteristics of developmental stage in response to pain? How do you adapt your approach based on developmental level? Step 2. Perform a Developmental or Cognitive Checkpoint
  • 80. Responses to Pain by Age or Development Age Group Understanding of Pain Behavioral Response Verbal Description Preschoolers 3–6 years (preoperational) Pain is a hurt; Does not relate pain to illness; may relate pain to an injury; Often believes pain is punishment; Unable to understand why a painful procedure will help them feel better or why an injection takes the pain away Active physical resistance, directed aggressive behavior, strikes out physically and verbally when hurt, low frustration level Has language skills to express pain on a sensory level; Can identify location and intensity of pain, denies pain, may believe his or her pain is obvious to others School-Age Children 7–9 years (concrete operations) Doesn’t understand cause of pain; Understands simple relationships between pain and disease and need for painful procedures to treat disease ; May associate pain with feeling bad or angry; recognize psychologic pain related to grief and hurt feelings Passive resistance, clenches fists, holds body rigidly still, suffers emotional withdrawal, engages in plea bargaining Can specify location and intensity of pain and describes pain physical characteristics in relation to body parts 10–12 years (transitional) Better understanding of relationship between an event and pain; More complex awareness of physical and psychologic pain,(moral dilemmas , mental pain) May pretend comfort to project bravery, may regress with stress and anxiety Able to describe intensity and location with more characteristics, able to describe psychologic pain Adolescents 13–18 years (formal operations) Has a capacity for sophisticated and complex under-standing of causes of physical and mental pain; Recognizes pain has qualitative and quantitative characteristics; Can relate to pain experienced by others Want to behave in socially acceptable manner -like adults; controlled response; May not complain if given cues from other healthcare providers More sophisticated descriptions with experience; may think nurses are in tune with their thoughts, so don’t need to tell nurse about their pain
  • 81. Step 3: Family Dynamic Checkpoint • Who is with the patient?- family, caregiver, etc. • Who is the legal guardian? • Who actually cares for the patient? • Who do you want at the bedside? • Consider culture, past experiences, time commitments, family personality, and family stress level Step 3. Family Dynamic Checkpoint
  • 82. Step 4: Facility (Agency/Community) Checkpoint • Staffing and setting • Community, rural, children’s hospital • Provider experience, team capabilities and expertise • Existing hospital/agency pain or procedural sedation policies • Acuity and overcrowding of the ED, hospital or clinic • Other priorities- MCI, natural disaster, etc. • Equipment, monitoring, backup Step 4. Facility Checkpoint
  • 83. Step 5: Patient Assessment Checkpoint • Review history, assessment and risk factors • Chronic illness-previous painful experiences, recent surgery • Psychiatric and mental considerations • Injury severity, +/- contraindications to opioids or sedation • Body habitus • Weight- ideal or real? Obesity? Step 5. Patient Assessment Checkpoint
  • 84. Step 6: Management Checkpoint: Choose Your “Recipe” • No magic recipe, must individualize and adjust “Ingredients” • Pharmacologic “ingredients” • Route: oral, nasal, IV, nebulized, topical, nerve blocks • Type: sucrose, NSAID, opioids, anxiolytics, ketamine • Nonpharmacologic “ingredients” • Everyone needs a little child life 101- distraction, music, virtual reality, etc. • Engage caregivers and parents- coaching, therapeutic language Always consider nonpharmacologic options +/- medications: Will pain duration be short (removal of FB, laceration repair), prolonged (burn) or chronic (rheumatologic)? Step 6. Management Checkpoint
  • 85. Step 7: Monitoring And Discharge Checkpoint • Joint Commission standards • Document reassessments • Patient should be back to baseline and tolerating fluids at discharge • Consider falls prevention and transportation- especially for patients on opioids or sedating medications • Discharge planning and instructions • Pain plan Step 7. Monitoring & Discharge Checkpoint 90
  • 87. PAMI Pain Management and Dosing Guide • The PAMI Pain Management and Dosing Guide is a free tool for use by health care providers in all settings and should be used as general guide when managing pain in pediatric and adult populations. • The guide provides treatment options for opioids, non-opioids, procedural sedation, nerve blocks, and IV/IM/IN/topical administration. It includes patient safety considerations as well as nonpharmacologic interventions. To take a tour of the dosing guide, click here! • A free downloadable pdf of the dosing guide can be accessed on the PAMI website. http://pami.emergency.med.jax.ufl.e du/resources/dosing-guide/ 92
  • 88. Opioid Prescribing and Equianalgesic Chart Generic (Brand) Onset (O) and Duration (D) Approximate Equianalgesic Dose Recommended STARTING dose for ADULTS Recommended STARTING dose for CHILDREN (> 6 mo) Oral IV Oral IV Oral IV Oral IV Morphine (MSIR®) [CII] O: 30-60 min D: 3-6 h O: 5-10 min D: 3-6 h 30 mg 10 mg 15-30 mg q 2-4 h 2-10 mg q 2-4 h 0.3 mg/kg q 4 h 0.1 mg/kg q 2-4 h Morphine extended release (MS Contin®) [CII] O: 30-90 min D: 8-12 h — 30 mg 10 mg 15-30 mg q 12 h — 0.3-0.6 mg/kg q 12 h — Hydromorphone (Dilaudid®) [CII] O: 15-30 min D: 4-6 h O: 15 min D: 4-6 h 7.5 mg 1.5 mg 2-4 mg q 4 h 0.5-2 mg q 2-4 h 0.06 mg/kg q 4 h 0.015 mg/kg q 4 h Hydrocodone/APAP 325 mg (Norco 5, 7.5, 10®) [CII] Hycet (7.5 mg/325 mg per 15 mL) O: 30-60 min D: 4-6 h — 30 mg — 5-10 mg q 6 h — 0.1-0.2 mg/kg q 4-6 h — Fentanyl [CII] (Sublimaze® Duragesic®) Patch for opioid tolerant patients ONLY Transdermal O: 12-24 h D: 72 h per patch O: immediate D: 30-60 min — 100 mcg (0.1 mg) Transdermal 12-25 mcg/h q 72 h 50 mcg q 1-2 h Transdermal 12-25 mcg/h q 72 h 1-2 mcg/kg q 1-2 h (max 50 mcg/dose)
  • 89. Non-Opioid Analgesics Generic (Brand) Adult Pediatric (<12 yo) Acetaminophen (Tylenol®) 325-650 mg PO q 4-6 h Max: 4 g/d or 1 g q 4 h 15 mg/kg PO q 4-6 h Max: 90 mg/kg/d Acetaminophen IV (Ofirmev®) Use only if not tolerating PO 1 g IV q 6 h Max: 4 g/d or 650 mg q 4 h prn pain <50 kg 15 mg/kg IV q 6 h or 12.5 mg/kg IV q 4 h prn pain Max: 75mg/kg/d Celecoxib (Celebrex®) 100-200 mg PO daily to q 12 h Max: 400 mg/d >2 yo 50 mg PO BID Ibuprofen (Motrin®) 400-800 mg PO q 6 to 8 h Max: 3200 mg/d 10 mg/kg PO q 6 to 8 h Max: 40 mg/kg/d or 2400 mg/d Ketorolac (Toradol®) 15-30 mg IV/IM q 6 h Max: 120 mg/d x 5 d 0.5-1 mg/kg/ dose IM/IV q 6 h Max: 15-30 mg q 6 h x 5 d Naproxen (Naprosyn®) 250-500 mg PO q 8 to 12 h Max: 1500 mg/d 5 mg/kg PO q 12 h Max: 1000 mg/d
  • 90. Intranasal* and Nebulized Medications Generic Dose Max Dose Comments Fentanyl IN: 1.5-2 mcg/kg q 1-2 h Neb: 1.7-3 mcg/kg 3 mcg/kg or 100 mcg Divide dose equally between each nostril Midazolam (5 mg/mL) IN: 0.3 mg/kg 10 mg or 1 mL per nostril (total 2 mL) Divide dose equally between each nostril Ketamine See Ketamine table Lidocaine Neb: 4% (40 mg/mL) 100-200 mg or 2.5-5 mL 4.5 mg/kg total or 300 mg >5 mg/kg associated with serious toxicity Ketamine (Ketalar®) Indications and Dosing Indications Starting Dose Procedural Sedation IV: Adult 0.5-1.0 mg/kg; Ped 1-2mg/kg; IM: 4- 5 mg/kg Sub-dissociative Analgesia^ IV: 0.1 to 0.3 mg/kg; IM: 0.5-1.0 mg/kg; *IN: 0.5-1.0 mg/kg Excited Delirium Syndrome IV: 1 mg/kg; IM: 4- 5 mg/kg
  • 91. Intranasal Medications • Use concentrated solution • Ketamine 50 mg/ml* • Fentanyl 50 mcg/ml* • Midazolam 5mg/ml • Use an atomizer • If > 1ml divide between nares • Aim spray toward turbinates/pinna *Rapid CSF levels 96
  • 92. Ketamine Pharmacology • Blockade of N-methyl D-aspartate (NMDA) receptors, peripheral Na+ channels and μ-opioid receptors providing sedation, amnesia, and analgesia. • High lipid solubility • allows rapid crossing of the blood-brain barrier, • quick onset of action (peak concentration at 1 minute-IV) • Rapid recovery to baseline 97 61
  • 93. Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Acute Pain Management • From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists (Reg Anesth Pain Med 2018;43: 456–466) • Evidence supports the use of subanesthetic ketamine for acute pain in a variety of contexts, including as a stand-alone treatment, as an adjunct to opioids, and, to a lesser extent, as an intranasal formulation.
  • 94. New Emphasis on Nonpharmacologic Methods of Treating Pain • Nonpharmacologic pain management techniques should be considered along with pharmacologic techniques and may: • improve assessment • decrease or avoid the use of opioids or anxiolytics • decrease time and recovery for procedures • decrease adverse events
  • 95. New Emphasis on Nonpharmacologic Methods of Treating Pain Painting Analogy Think of nonpharmacologic management as your “base coat” or “primer” before applying additional coats of analgesic treatment. With the right base coat foundation, you have a better chance of painting a patient’s symptoms a more tolerable and long-lasting new color. (PEM Playbook: http://pemplaybook.org/podcast/pediatric-pain/
  • 96. The Importance of Incorporating Nonpharmacologic Methods When Treating Pain In an effort to encourage multimodal approaches, hospitals are now required to incorporate nonpharmacologic interventions in pain management plans. These pain assessment and management requirements are designed to improve the quality and safety of care provided by Joint Commission-accredited hospitals. Click on the link to find out more! https://www.jointcommission.org/assets/1/18/Joint_Commission_ Enhances_Pain_Assessment_and_Management_Requirements_for_ Accredited_Hospitals1.PDF 101
  • 97. Categorization of Nonpharmacologic Interventions Physical (Sensory) Interventions Positioning Cutaneous stimulation Nonnutritive sucking, sucrose Pressure Hot or cold treatments Others Cognitive-Behavioral Interventions Psychologic preparation, education, information Distraction (passive or active): Video games, TV, movies, phone, lighted or interactive toy, virtual reality Relaxation techniques (breathing, meditation, etc.) Music Guided imagery Training and coaching Coping statements: “I can do this” Adapted from: Murray KK, Hollman GA. Non-pharmacologic interventions in children during medical and surgical procedures. In: Tobias JD, Cravero JP, eds. Procedural Sedation for Infants, children, and adolescents; Section on Anesthesiology and Pain Medicine. American Academy of Pediatrics ; 2016.
  • 98. Nonpharmacologic Interventions • Pain can sometimes be adequately managed using nonpharmacologic interventions such as ice, splinting, distraction, etc. • These management options can be applied singly or as adjuncts along with pharmacological options. Click here for more information on nonpharmacologic management options. For additional information and resources refer to the website and the Nonpharmacologic PAMI module. 103
  • 99. Develop Your Own Distraction & Nonpharmacologic Pain Toolkit Virtual Reality Distraction & Nonpharmacologic Pain Toolkit
  • 100. b. Re-assessment of Pain 105
  • 101. Re-assessment of Pain • Timely reassessment of pain is essential. One of the most common mistakes made in pain management is failure of reassessment after an intervention (pharmacologic or nonpharmacologic). • Pain level should be reassessed after an intervention, such as medication administration, and once the intervention has had time to exert its effect. • The timeframe and frequency for re-assessment will depend on the setting.  For example, re-assessments will be performed frequently and over a shorter time course in acute care settings, like the ED, compared to outpatient settings.  In the acute care settings, consider reassessing pain level 30 minutes after IV and 60 minutes after PO administration of a medication. 106
  • 102. Re-assessment of Pain • The same scale or scoring system used previously should be used on re- assessment for consistency. • All patients do not respond to identical management in the same manner due to genetic and other factors. • Appropriate monitoring for respiratory depression should be used especially when using pain relievers with sedating effects (opioids). • Pain should always be reassessed at time of discharge or within an appropriate time interval in the outpatient setting. The literature suggests that a 33% to 50% decrease in pain intensity is clinically meaningful from a patient's perspective and represents a reasonable standard of intervention efficacy for acute and chronic pain. 107
  • 103. c. Consequences of Unrelieved Pain 108
  • 104. Consequences of unrelieved acute pain Psychological Impacts • The psychological impact of untreated pain can include post-traumatic stress disorder, anxiety, catastrophizing, and depression. Chronic pain syndromes • Chronic pain syndromes can develop as a consequence of untreated acute pain mechanisms including spinal cord hyper-excitability. Mortality and Morbidity • Increased mortality and morbidity can result from unrelieved acute pain. This can occur through increased oxygen demand, increased metabolic rate, cardiovascular and pulmonary complications, and impaired immune function. 109
  • 105. Chronic Pain Syndrome Chronic pain can affect sleep, mood, activity, and energy level. It has both physical and psychological affects that can result in a detrimental cycle. 110
  • 106. 6. Discharge Planning and Transitions of Care 111
  • 107. Discharge Planning for Patients with Pain • Appropriate discharge planning should take into account what interventions the patient has received during the visit and transportation home. • How will the patient safely arrive home? Consider patient transportation and driving precautions, especially after receiving a sedating medication • Are they ambulating at their baseline without assistance? • Could the treatment or medication still be exerting its effects (i.e. lethargy as a side effect of morphine)? • An important consideration during discharge planning is whether the patient will be able to safely take the prescribed medications at home. Also consider if the patient will be able to obtain the prescribed medications from their pharmacy? (ie cost, supply, etc.). • Patients should be educated on the proper use of their prescribed medications with clear and easy to understand instructions: potential side effects, interactions with other prescribed medications and any adverse effects. • Has the patient been advised to: • Not drive while taking their prescribed opioid • Not combine their medication with alcohol • Not take more than prescribed especially for acetaminophen containing products • Store medications safely and dispose of unused tablets properly 112
  • 108. Pain Management Transitions of Care Sound management of pain during transitions of care is important because:  It reduces return visits  Expedites return to normal activities and work  Helps reduce risk of acute pain progressing to chronic pain Patients often take 4-6 weeks to experience pain reduction after an acute injury! Yet national guidelines support limiting opioid prescriptions to a week or less. 113 This is why use of multimodal interventions and timely follow up is important.
  • 109. 7. Patient Safety, Regulatory and Legal Aspects of Pain Management 117
  • 110. Institution, Local, State, and Federal Regulations Providers must be familiar with regulations regarding pain management at their institution and at the local, state, and federal levels. Most states now have PDMPs (prescription drug monitoring programs) and opioid legislation. 118
  • 112. Case Scenario 1 A 54 year-old non-English speaking male is brought to the ED by EMS after sustaining a motorcycle collision approximately 20 minutes prior to arrival. He has an obvious deformity to his left femur and multiple areas of “road rash.” He received no pain medications prior to arrival. His left leg is splinted. His eyes are closed and he appears to be praying. After physical exam and x-rays, it is determined that he has a left femur fracture and profuse areas of abrasions and denuded skin contaminated with dirt and gravel. A second patient arrives during your assessment of the first patient. Patient number 2 is a 23 year-old female that was involved in the same accident. She was the restrained backseat passenger in a pick-up truck, reports “pain all over” and is crying hysterically. After a thorough exam she is determined to have mild musculoskeletal strain and one small contusion of her forehead.  What factors account for the different reactions to pain in these two patients?  What are the potential barriers to adequately assessing their pain? 120
  • 113. Case Scenario 1 Discussion • Patients respond to and express their degree of pain differently due to a number of psychosocial factors. The severity of injury alone does not always dictate the degree of a patient’s pain. • In this case, patient 1 objectively has sustained more severe injuries. However, patient 2 presents with a more intense and dramatic response to her injury and situation. • There are many barriers the treatment team faces when assessing and treating these two patients, including language barriers (patient 1), lack of previous physician-patient relationship, simultaneous evaluation of potentially critical patients, and lack of knowledge regarding past pain experiences. 121
  • 114. Case Scenario 2 A 3 year-old right-handed male presents to his pediatrician’s office with his caregiver who reports that the child has complained of pain in his right arm since yesterday. When questioned the child denies pain, but cries and pulls away when any part of the right upper extremity is touched. He has no obvious deformity or swelling to either arm.  How would your approach to pain assessment in this child differ from that of an adult? From an adolescent? 122
  • 115. Case Scenario 2 Discussion • Pediatric patients require a different pain assessment approach from adults as they often cannot adequately communicate their pain symptoms or the severity. • There are several resources clinicians can use in addition to patient report. These include pediatric pain scales, observation of the patient’s behavior, and question • You notice the patient to be playful and interactive, but not using his right arm. Although the child is attempting his normal behaviors (such as playing), he is doing so through compensation. This is confirmed via his caregiver stating that he has been favoring his left arm. • You hand him two toys and he attempts to hold both toys using his left hand. As he is distracted with the toys, you are able to palpate his entire upper extremity and determine that his pain is localized to the elbow. Through the use of observation, surrogate history provided by the caregiver, and distraction you are able to localize the patient’s pain. 123
  • 116. Case Scenario 3 • A 53 year-old male with chronic back pain underwent knee replacement one week ago. He presents to his primary care doctor complaining of persistent post-op pain. The patient reports his prescribed opioid is not controlling his pain. His pain has greatly limited his ability to perform his daily living activities.  How would you manage this patient’s pain? What important questions regarding his history should be asked? 124
  • 117. Case Scenario 3 • This patient suffers with chronic back pain which he treats with a prescription opioid. It is important to ask the patient how long he has been receiving prescription opioids and at what dose. Also if he was prescribed any new medications after his surgery. • Upon further inquiry, the patient indicates that he has been taking the same opioid medication at the same dose for three years. It has always controlled his pain until his knee surgery. He reports that he was not given any new prescriptions for pain after his surgery. He was told that he should take ibuprofen as needed for pain. 125
  • 118. Case Scenario 3 • In this case, the patient is suffering with an increase in his baseline pain due to his recent surgery. The prescription opioid which had controlled his pain for years is no longer effective given this increase in pain. It is important to recognize that patients who have taken the same prescription opioids for significant period of time may need an increase in dose. Additionally, this patient would likely benefit from a multimodal approach utilizing other non-opioid pharmacologic and nonpharmacologic adjuncts. 126
  • 120.  Pain is complex and multifactorial.  There are several different classifications of pain depending on location and etiology.  Successful management of pain relies on a thorough pain history and exam, a stepwise approach, timely re-assessments, and appropriate selection of pharmacological and nonpharmacologic management options.  There is no test that can adequately identify or measure pain.  Chronic pain is a potential outcome of untreated acute pain.  Discharge planning must take into account several safety concerns and should be centered on patient education. 128 Summary