Pec11 chap 08 pathophysiology

This document discusses the components necessary for adequate cellular perfusion. It begins by explaining cellular metabolism, including aerobic and anaerobic metabolism. Aerobic metabolism requires oxygen to produce significant ATP through a series of steps in the mitochondria. The document then outlines the key components required for adequate perfusion to deliver oxygen and nutrients to cells and remove waste. This includes composition of air, airway patency, ventilation mechanics, gas transport in blood, blood pressure and more. Any disruption to these components can lead to hypoxia and a shift to less efficient anaerobic metabolism.