Phase ii training case 2
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A 53-year-old man experienced severe chest pain for 6 hours and was found to have tachycardia. Laboratory tests showed high serum troponin levels and an angiogram revealed over 90% blockage of the left anterior descending artery. In this scenario of myocardial infarction, irreversible injury to heart muscle fibers would occur when the cell nuclei undergo karyorrhexis.
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Phase ii training case 2
- 1. Phase II, General Pathology Training Cases. 18/10/2010<br />Student Name:<br />Question 3 <br />A 53-year-old man has experienced severe chest pain for the past 6 hours. On physical examination he is afebrile, but has tachycardia. Laboratory studies show a serum troponin I of 10 ng/mL. A coronary angiogram is performed emergently and reveals >90% occlusion of the left anterior descending artery. In this setting, an irreversible injury to myocardial fibers will have occurred when which of the following cellular changes occurs? <br />A Glycogen stores are depleted <br />B Cytoplasmic sodium increases <br />C Nuclei undergo karyorrhexis <br />D Intracellular pH diminishes <br />E Blebs form on cell membranes <br />