Popherbsppt(2)

Editor's Notes

• #2: Illustration: Morning Glories, Ipomoea spp. Unless otherwise noted, text, structure drawings & photographs are © Lisa Ganora 2003. Other photographers are credited on the slides & in the notes. Botanical illustrations may be modified from: 1. Köhler: Köhlers Medizinal-Pflanzen in naturgetreuen Abbildungen und kurz erläuterndem Texte Franz Eugen Köhler, Gera, Germany. 1883-1914. Digital images courtesy of: Kurt Stueber at http://caliban.mpiz-koeln.mpg.de/~stueber/koehler/ 2. Walcott: Mary Vaux Walcott. Digital images online at SWSBM: http://www.ibiblio.org/pub/academic/medicine/alternative-healthcare/herbal-medicine/SWSBM/Images/Walcott.html 3. NGS: Digital images online at SWSBM: http://www.ibiblio.org/pub/academic/medicine/alternative-healthcare/herbal-medicine/SWSBM/NGSImages/NGS.html 4. Lindman: Carl Axel Magnus Lindman: Bilder ur Nordens Flora (1901-1905). Digital images courtesy of Project Runeberg (Sweden) http://www.lysator.liu.se/runeberg/nordflor/ & Kurt Stueber at http://caliban.mpiz-koeln.mpg.de/~stueber/lindman/ 5. Thomé: Prof. Dr. Otto Wilhelm Thomé, Flora von Deutschland Österreich und der Schweiz, 1885, Gera, Germany. Digital images courtesy of Kurt Stueber, http://www.biolib.de 6. SWSBM: Michael Moore at the Southwest School of Botanical Medicine maintains a large online library of medicinal plant images. See his site at: http://www.ibiblio.org/pub/academic/medicine/alternative-healthcare/herbal-medicine/SWSBM/HOMEPAGE/ 7. Raimondi: Antonio Raimondi, c. 1866. illustration courtesy ofhttp://www.ciaraimondi.edu.pe/Acuarelas%20de%20Antonio%20Raimondi.htm In the chemical structures that follow, different colors represent different atoms: Cyan: hydrogen atoms Magenta: carbon atoms Red: oxygen atoms Blue: nitrogen atoms Yellow: sulfur atoms Copyright Notice All material (other than photographs copyrighted to others, as noted, & original historical botanical illustrations as listed above) in Healing Herbs: Supportive Science for Herbal Medicine is © 2003 Lisa Ganora. Copyright protected under the Digital Millennium Copyright Act [http://www.copyright.gov/legislation/hr2281.pdf]. Any use of materials in this presentation, including reproduction, distribution, or republication, without prior written permission of the author, is strictly prohibited. All rights reserved. The information presented here is for educational purposes only. It is based on scientific studies, clinical results, or traditional usage as noted. The effects listed may not necessarily occur in all individuals. This information is not a substitute for health care from qualified practitioners.
• #3: Illustration: TR: Alfalfa, Medicago sativa [NGS/SWSBM] BR: Biochanin A, one isoflavone found in Alfalfa leaves; genistein & daidzein are also present. The isoflavones in Alfalfa are types of polyphenolic compounds. For more information on phytoestrogens, see: http://www.herbalchem.net/phytoestrogens_and_human_health.htm
• #4: Illustrations: L: Bilberry, Vaccinium myrtillus [Thomé/Stueber], is closely related to Blueberry. M: Procyanidin B3 is one kind of proanthocyanidin, which is a kind of flavonoid, which is a kind of polyphenol. TR: Cyanidin, an anthocyanidin aglycone; anthocyanidins are a type of flavonoid, which is a type of polyphenolic compound. The glycosides of anthocyanidins are called anthocyanins. Aglycone: molecule without a sugar or sugars attached. Glycoside: molecule with one or more sugars attached.
• #5: Illustrations: L: Bilberry, Vaccinium myrtillus [Thomé/Stueber], is closely related to Blueberry. M: Procyanidin B3 is one kind of proanthocyanidin, which is a kind of flavonoid, which is a kind of polyphenol. TR: Delphinidin, another common anthocyanidin aglycone; anthocyanidins are a type of flavonoid, which is a type of polyphenolic compound. Aglycone: molecule without a sugar or sugars attached. Glycoside: molecule with one or more sugars attached.
• #6: Illustrations: L: Black Cohosh (Actea racemosa) leaf R: Cimicifugoside, a triterpene glycoside; it is a type of terpenoid compound. Black Cohosh reduces LH (luteinizing hormone) activity which is associated w/hot flashes. See: http://www.herbalchem.net/phytoestrogens_and_human_health.htm#Black%20cohosh
• #7: Illustrations: TR: Juglone, a naphthoquinone, which is a type of quinone, which is a polyphenolic compound. R: Black Walnut, Juglans nigra, tree & immature nuts Juglone is responsible for the dark brown stain from Walnut hulls; it is also allelopathic (discourages the growth of competing plants). See: http://ntp-server.niehs.nih.gov/htdocs/Chem_Background/ExSumPdf/Juglone.pdf for information on juglone toxicology.
• #8: Illustrations: TL: Burdock leaf, Arctium lappa BL: Burdock seeds Oligo = short; oligosaccharides are short chains of monosaccharide (simple sugar) units. Some oligosaccharides occur free & others act as the sugar components of glycosides (a glycoside is a molecule with sugar unit(s) attached. Relative inulin content: Chicory > Burdock > Sunflower roots (Jerusalem Artichoke) > Dandelion > Garlic > Leek, Artichoke > Onion See: USDA, http://www.ba.ars.usda.gov/hb66/075jerusalem.pdf Lignans in Burdock include arctiin & arctigenin. Polyacetylenes are related to the tingly isobutylamides in Echinacea, & have activity in the immune system.
• #9: Illustrations: L: Cascara sagrada, Rhamnus purshiana [Köhler/Stueber] R: Cascaroside A, one of the anthraquinones in Cascara; it is a type of quinone, which is a type of polyphenol. The anthraquinone glycosides in Cascara are responsible for the laxative effect.
• #10: Illustrations: TR: Cayenne peppers, Capsicum frutescens BR: Capsaicin Capsaicin, the spicy compound in Cayenne, is sometimes classified as an alkaloid because of its nitrogen atom & its origin from amino acids. Other systems classify it as a phenylpropanoid derivative rather than as an alkaloid. Capsorubin & capsanthin are types of xanthophylls, which are a kind of carotenoid (aka tetraterpene), which is a kind of terpenoid compound.
• #11: Illustrations: TR: Cayenne peppers, Capsicum frutescens BR: Capsanthin Capsaicin, the spicy compound in Cayenne, is sometimes classified as an alkaloid because of its nitrogen atom & its origin from amino acids. Other systems classify it as a phenylpropanoid derivative rather than as an alkaloid. Capsorubin & capsanthin are types of xanthophylls, which are a kind of carotenoid (aka tetraterpene), which is a kind of terpenoid compound.
• #12: Illustrations: Background: Dried Cranberries, Vaccinium oxycoccus or V. macrocarpon TR: Cranberry plant [NGS/SWSBM] Cranberry contains unique proanthocyanidins that have been demonstrated to inhibit bacterial binding to urinary tract epithelium. Many of these are based on linked epicatechin units.
• #13: Illustrations: TR: Dandelion, Taraxacum officinale [NGS/SWSBM] B: Dandelion blossoms in Colorado Inulin is an oligosaccharide (a type of polysaccharide). Sesquiterpene lactones – bitter principles – are a subtype of sesquiterpenes, which are a kind of terpene. Oligo = short; oligosaccharides are short chains of monosaccharide units. Some kinds occur free & others act as the sugar components of glycosides. Relative inulin content: Chicory > Burdock > Sunflower roots (Jerusalem Artichoke) > Dandelion > Garlic > Leek, Artichoke > Onion See: USDA, http://www.ba.ars.usda.gov/hb66/075jerusalem.pdf
• #14: Illustrations: L: Echinacea angustifolia R: Echinacea purpurea Immunomodulating polysaccharides are special kinds of polysaccharides, which are long chains of simple sugar units. They are a type of carbohydrate.
• #15: Illustrations: T: Echinacea purpurea B: Cichoric acid Cichoric acid is a caffeic acid derivative (a type of phenylpropanoid, which is a type of polyphenol), found as a major constituent of E. purpurea & a minor constituent of E. angustifolia. It contributes to the immunostimulant properties. See: http://www.naturalproducts.org/inpr/mono_html/echin_html/echin_chem1.html See: http://www.thorne.com/altmedrev/fulltext/ech.html [Kerry Bone]
• #16: Illustrations: L: Elderberries, Sambucus canadensis R: Elder bush laden with berries in the late summer. Cyanin is a glycoside of cyanidin, delphinin is a glycoside of delphinidin. They are found in Bilberries, Blueberries, Elderberries, Black Cherries, etc. All of these are types of anthocyanins, which are types of flavonoids, which are types of polyphenols.
• #17: Illustrations: TR: Parthenolide, a sesquiterpene lactone (a subtype of sesquiterpene, which is a type of terpenoid compound; they are found in essential oils). BR: Feverfew, Tanacetum parthenium
• #18: Illustrations: Flax (Linum usitatissimum) oil & seeds Flax is the best source of the essential fatty acid, ALA. Our bodies cannot make this substance, so we must obtain it from the diet. It is important for the production of anti-inflammatory prostaglandins. See: http://www.nhir.com/tests/FlaxSeedOil.pdf (a continuing ed module on Flax) See: http://www.agr.gc.ca/food/nff/cancrops/crops.pdf (health effects of Flax & other oils) See: http://www.ourfood.com/Food_what_is_it.html#SECTION001000100000000000000 (phytosterol information)
• #19: Illustrations: L: Secoisolariciresinol, a lignan, is a type of polyphenol made up of two phenylpropanoid units. R: Matairesinol is closely related to secoisolariciresinol, but occurs in smaller amounts. Flax is also the best dietary source of these two lignans. They have a mild phytoestrogenic effect & can help prevent cancers.
• #20: Illustrations: TR: Allicin, the antimicrobial sulfur compound in Garlic. BR: Garlic, Allium sativum The sulfur compounds in Garlic are all derived from the amino acid, cysteine. Sulfur gives them their spiciness & pungent smell. These compounds are classified as amino acid derivatives. See: www.herbalchem.net (Garlic pages are in the archives) for detailed information on Garlic chemistry.
• #21: Illustrations: L: Alliin, a precursor of allicin. M: Alliinase, the enzyme which mixes with alliin when Garlic is crushed, & transforms it into allicin. R: Allicin, the spicy, pungent antimicrobial compound. Allicin is rather unstable, and transforms itself into sulfides (if in air or water) & if in oil, ajoenes & dithiins. See: www.herbalchem.net (Garlic pages are in the archives) for detailed information on Garlic chemistry.
• #22: Illustrations: TL: Alliin: a cysteine sulfoxide, parent of allicin TM: Allicin: an antimicrobial compound; breaks down over time TR: Diallyl disulfide: cardiovascular benefits; sulfides are formed in water & air BL: Garlic, Allium sativum BR: Vinyl dithiins, formed when Garlic is macerated in oil (ajoenes are also formed in oil) See: www.herbalchem.net (Garlic pages are in the archives) for detailed information on Garlic chemistry.
• #23: Illustrations: L: Ginger (Zingiber officinalis) root R: Ginger plant [Köhler/Stueber] Gingerols are not volatile (not part of the essential oil). When Ginger is dried, they transform into shogaols. Many other compounds in Ginger contribute to its medicinal actions, including monoterpenes & sesquiterpenes in the essential oil. COX-2 stands for cyclo-oxygenase 2, an enzyme that mediates the inflammatory process; so COX-2 inhibitors are anti-inflammatory.
• #24: Illustration: Structure: [6]-gingerol; it occurs with many other similar compounds. Gingerols are not volatile (not part of the essential oil). When Ginger is dried, they transform into shogaols. Many other compounds in Ginger contribute to its medicinal actions, including monoterpenes & sesquiterpenes in the essential oil. COX-2 stands for cyclo-oxygenase 2, an enzyme that mediates the inflammatory process; so COX-2 inhibitors are anti-inflammatory.
• #25: Illustration: Ginkgo biloba [Photo © Martin Wall, http://www.herbslides.com/]
• #26: Illustration: Ginkgo biloba leaves Besides flavonols, Ginkgo contains proanthocyanidins (a type of flavonoid, which is a type of polyphenol). See: http://www.who.int/medicines/library/trm/medicinalplants/pdf/154to167.pdf for a monograph on Ginkgo.
• #27: Illustration: Ginkgolide A, one of the diterpene lactones in Ginkgo. It is a type of terpenoid. See: http://www.who.int/medicines/library/trm/medicinalplants/pdf/154to167.pdf for a monograph on Ginkgo.
• #28: Illustrations: American Ginseng, Panax quinquefolius. Ginsenosides & quinquenosides are types of steroidal saponins. They are ‘steroidal’ because they are based on a steroid nucleus that is very similar to the nucleus of steroidal hormones in humans. They are rather similar to triterpenoid saponins, a type of terpenoid glycoside. ‘Panax’ comes from Greek, pan (all) & akos (cure).
• #29: Illustrations: L: Goldenseal plants, Hydrastis canadensis R: Oregon Grape berries, Mahonia repens The roots of both of these plants are bright yellow because of berberine-type alkaloids. These alkaloids are a subtype of the isoquinoline alkaloids.
• #30: Illustrations: L: Hydrastine, an alkaloid from Goldenseal (Hydrastis canadensis) R: Goldenseal sprouts [Photo courtesy of www.hebes.mdx.ac.uk/.../ Garden%20Pictures%20Page%205.htm] Berberine is a water-soluble alkaloid, which will extract in water infusions. Hydrastine is soluble in alcohol/water, so it extracts in tinctures. Both of these yellow alkaloids are bitter, antimicrobial compounds.
• #31: Illustrations: L: Berberine, a water-soluble yellow alkaloid. R: Oregon Grape (Mahonia repens) flowers. Oregon Grape root can be used instead of Goldenseal, which has been over-harvested & is becoming very rare.
• #32: Illustrations: L: Grapes, Vitis vinifera [Köhler/Stueber] R: Procyanidin C2, one of the OPC’s found in Grape seed extract. Grape seed extract is quite similar to Pycnogenol®; both contain mainly OPC’s. There are many different kinds of OPC’s; the illustration is just one type. These molecules are made up of linked units of catechin or epicatechin, which are flavonols, which are a type of flavonoid. All of these are polyphenolic compounds.
• #33: Illustrations: TR: Hawthorne (Crataegus spp.) [NGS/SWSBM] BR: Hawthorne berries Hyperin (aka hyperoside; quercetin-3-galactoside) is also found in St. Johnswort (Hypericum perforatum). It is a type of flavonol glycoside, which is a type of flavonoid, which is a type of polyphenol.
• #34: Illustrations: R: Kava Kava, Piper methysticum [Photo © Martin Wall, http://www.herbslides.com/] L: Methysticin, a kavalactone, is a type of styrylpyrone, which is a type of polyphenolic compound; other kavalactones include yangonin & kawain.
• #35: Illustrations: TR: Licorice, Glycyrrhiza glabra [Thomé/Stueber] BR: Isoliquiritigenin, a chalcone, which is a type of polyphenolic compound. See: http://www.chiro.org/nutrition/ABSTRACTS/Flavonoids_Inhibit_Cell_Growth.shtml re melanoma.
• #36: Illustrations: TR: Liquiritigenin, a flavanone, which is a type of flavonoid, which is a type of polyphenol. BR: Candy made with Licorice (Glycyrrhiza glabra) extract. The yellow color of Licorice root is due to its flavonoids.
• #37: Illustrations: TR: The Moon, which may have nothing to do with Licorice, but looks pretty there. BR: Licorice, Glycyrrhiza glabra [Köhler/Stueber]. Triterpenoid saponins are usually anti-inflammatory compounds, & are found in most herbs used for arthritis, joint inflammation, etc. They are a type of terpenoid.
• #38: Illustration: L: Lobeline, a piperidine alkaloid. R: Lobelia, Lobelia inflata [[Köhler/Stueber]. Lobeline & its relatives (lobelanine & lobelanidine) are found in Lobelia (Lobelia inflata). Lobeline is a respiratory stimulant acting on the brain centers & carotid chemoreceptors that regulate breathing; also a bronchodilator & antispasmodic for asthma & bronchitis. It stimulates nicotinic receptor sites, so the herb is traditionally used to reduce nicotine cravings. Large doses are emetic & toxic. For Eclectic usage see: http://www.ibiblio.org/herbmed/eclectic/kings/lobelia.html
• #39: Illustrations: L: Marsh Mallow, Althea officinalis [SWSBM] R: Other Mallow species (T, from the Southern California desert; B, from the Front Range in Colorado) are also mucilaginous. Mucilage is a type of heteropolysaccharide, which is a type of carbohydrate. The original "marshmallows" were actually made by boiling down the sweet mucilage of the Marsh Mallow. Okra is a mallow.
• #40: Illustrations: TL: Milk Thistle (Silybum marianum) flower. BL: Silybin, one component of silymarin; silydianin & silychristin are others. Technically, these molecules are made of a phenylpropanoid unit bonded to a flavonol unit; both of these are types of polyphenols.
• #41: Illustrations: TL: Milk Thistle (Silybum marianum) flower.
• #42: Illustrations: Background: Nettles, Urtica dioica Insets: Formic acid, Histamine, & Nettle stingers. Formic acid is an organic acid that is also found in ant stings. Histamine is a mediator of the inflammatory process; in the human body, it is released during allergic reactions & causes itching, swelling, redness, etc. Nettle stingers are made from silica; they release their chemicals when brushed against.
• #43: Illustration: Neem, Azadirachta indica [Photo © William Ciesla, http://www.forestryimages.org/browse/subimages.cfm?sub=7046] The terpenoid compounds in Neem include complex triterpenoids also known as limonoids.
• #44: Illustration: Passionflower, Passiflora incarnata [NGS/SWSBM] Harman alkaloids are a type of indole alkaloid; harman is also known as passiflorine. This type of alkaloid is sometimes referred to as a ‘beta-carboline’ alkaloid. They are neuroactive. Flavonoids include glycosides of the flavones luteolin & apigenin, along with flavonol glycosides based on quercetin & kaempferol (all of these flavonoids are types of polyphenolic compounds).
• #45: Illustrations: L: Plantain, Plantago major [Thomé/Stueber] R: Aucubin, an iridoid, which is a subtype of monoterpene, which is a type of terpenoid compound).
• #46: Illustrations: TR: Seed capsules of Plantain. BR: Broad-leaf Plantain, Plantago major. Psyllium seed (from Plantago spp.) contains mucilage (a type of dietary fiber) that is not degraded by the digestive process or by colon bacteria; hence it survives to have a mechanical effect on intestinal motility. It also brings about a modest decrease in serum cholesterol levels, perhaps by increasing fecal elimination & decreasing intestinal resorption of bile acids & cholesterol. Plantain leaves also contain a type of mucilage known as heteroxylans, which contains units of the simple sugar, xylose, along with other simple sugars.
• #47: Illustrations: L: English or Narrow-leaf Plantain, Plantago lanceolata. TR: Aucubin, an antiseptic iridoid glycoside. BR: Broad-leaf Plantain, Plantago major. Polyvalent: having multiple modes of action. Plantago major & P. lanceolata contain: Iridoids: aucubin [0.3-2.5%], catalpol [0.3-2.1%], asperuloside; these are subtypes of monoterpenes, which are types of terpenoids. Flavonoids, which are polyphenols. Phenolic acids, another kind of polyphenol. Phenylpropanoid glycosides, another kind of polyphenol. Tannins are also known as proanthocyanidins, & are a kind of flavonoid, which is a kind of polyphenol. Mucilage is a type of heteropolysaccharides containing many linked sugar units. References: Chiang, L.C., et. al. 2002. Antiviral activity of Plantago major extracts and related compounds in vitro. Antiviral Research 55:53-62. Rønsted et. al. 2000. Chemotaxonomy of Plantago. Iridoid glycosides and caffeoyl phenylethanoid glycosides. Phytochemistry 55:337-348. Samuelsen, Anne Berit. 2000. The traditional uses, chemical constituents and biological activities of Plantago major L. A review. Journal of Ethnopharmacology 71:1-21.
• #48: Illustration: Red Clover, Trifolium pratense [Lindman/Stueber].
• #49: Illustrations: R: Red Clover, Trifolium pratense The isoflavones are a type of polyphenol.
• #50: Illustrations: L: Biochanin A, an isoflavone from Red Clover leaves. R: Formononetin, another isoflavone from Red Clover leaves. The isoflavones are a type of polyphenol.
• #51: Illustrations: TL: Rosemary (Rosmarinus officinalis) flower [Köhler/Stueber]. BL: Rosemary sprig. R: Rosmarinic acid, a dimeric phenylpropanoid, is a type of polyphenolic compound. Numbers: Phenylpropanoids have phenolic rings, with 3-carbon side chains. This molecule has two pheylpropanoids bonded together; the three carbons of each side chain are numbered. Rosemary is known as the ‘herb of remembrance,’ perhaps because these antioxidant compounds help protect the brain & nervous system. See: http://www.florahealth.com/flora/home/canada/healthinformation/encyclopedias/Rosemary.asp for constituents in Rosemary leaf.
• #52: Illustrations: TL: Rosemary (Rosmarinus officinalis) flower [Köhler/Stueber]. BL: Rosemary sprig. Rosemary is known as the ‘herb of remembrance,’ perhaps because these antioxidant compounds help protect the brain & nervous system. See: http://www.florahealth.com/flora/home/canada/healthinformation/encyclopedias/Rosemary.asp for constituents in Rosemary leaf.
• #53: Illustration: Background: Sage, Salvia officinalis R: Thujone, a monoterpene found in Sage, is also in Wormwood (Artemisia absinthium). Phenylpropanoids are a type of polyphenolic compound. Diterpenes are a type of terpenoid compound. Thujone is a monoterpene, which is a type of terpenoid. Cineole is also a monoterpene. Proanthocyanidins are a type of flavonoid, which is a type of polyphenolic compound.
• #54: Illustration: R: St. Johnswort, Hypericum perforatum [NGS/SWSBM].
• #55: Illustrations: L: Hypericin, a type of anthraquinone derivative known as a bianthraquinone or naphthodianthrone (which are types of polyphenols); this is the compound that makes Hypericum oil red. M: Hyperforin, a type of phloroglucinol derivative, which is an unusual type of polyphenolic compound. R: St. Johnswort, Hypericum perforatum [NGS/SWSBM].
• #56: Illustrations: TR: Norathyriol, a type of xanthone, which is a type of polyphenol. BR: St. Johnswort, Hypericum perforatum.
• #57: Illustration: Saw Palmetto, Serenoa repens [Photo © Martin Wall, http://www.herbslides.com/]. Lipidosterolic means that the extracts contains both lipids (fatty acids) & phytosterols or plant steroidal compounds. The concentrated extract of these oil-soluble substances is best. A CO2 extract will not have traces of potentially harmful solvents. No one chemical has been singled out as the ‘active ingredient.’
• #58: Illustrations: Background: Turmeric powder. TL: Turmeric, Curcuma longa [Raimondi]. Curcuminoids are a special class of polyphenols found in Turmeric.
• #59: Illustration: Curcumin, one of the curcuminoids. It is a type of polyphenol known as a ‘diarylheptanoid.’
• #60: Illustrations: L: Valtrate (valtratum), a free (non-glycoside) iridoid. Iridoids are a special type of monoterpenes, which are a type of terpenoid compound. R: Valerian, Valeriana officinalis [NGS/SWSBM]. The sedative sesquiterpenes in Valerian include valerinic acids. Sesquiterpenes are another kind of terpenoid compound. No one constituent has been identified as the ‘active ingredient’ of Valerian.
• #61: Illustrations: L: Valerian, Valeriana officinalis [NGS/SWSBM]. R: Valerenic acid, a bicyclic sesquiterpene. Sesquiterpenes are a kind of terpenoid compound.
• #62: Illustration: Milkweed (Asclepias speciosa) pod bursting open in fall. Copyright Notice All material (other than photographs copyrighted to others, as noted, & original historical botanical illustrations as listed at beginning of show) in Healing Herbs: Supportive Science for Herbal Medicine is © 2003 Lisa Ganora. Copyright protected under the Digital Millennium Copyright Act [http://www.copyright.gov/legislation/hr2281.pdf]. Any use of materials in this presentation, including reproduction, distribution, or republication, without prior written permission of the author, is strictly prohibited. All rights reserved. The information presented here is for educational purposes only. It is based on scientific studies, clinical results, or traditional usage as noted. The effects listed may not necessarily occur in all individuals. This information is not a substitute for health care from qualified practitioners. Contact: Lisa Ganora, info@herbalchem.net