This study examined the incidence and severity of post-dural puncture headache (PDPH) in 151 patients who underwent spinal anesthesia with a 25-gauge needle for cesarean section. The results found that 21 patients (14%) reported PDPH after the procedure. Most PDPH cases were mild to moderate in severity. Onset of PDPH was typically 1-2 days post-procedure. The study recommends further research with larger sample sizes and higher gauge needles to determine the best preventative measures for reducing the incidence of PDPH following spinal anesthesia.