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ASD Device Closure Why and How
Dr. Chandra Mani Adhikari
Cardiologist
Shahid Gangalal National Heart Centre
Associate Professor
National Academy of Medical Sciences
ASD secundum
• Accounts for 10% of congenital heart disease at
birth.
•As much as 30% to 40% in adults who present
with congenital heart disease.
•More frequent in Females.
J Cardiovasc Ultrasound 2007;15(1):1-7
Surgical closure for ASD
• For many years has been the gold standard treatment.
• is a safe and effective with negligible mortality.
N Engl J Med 2000;342:256-63.
Surgical closure is associated with morbidity
• Bypass related complications
• Sternotomy/thoracotomy
• Scar (specially young unmarried patients)
N Engl J Med 1990;323:1645-50.
Even the surgeon needs to think of cosmetic things
• As most of the patients are young females
• Emphasis has been placed on shorter incisions
• “less” or “minimally” invasive techniques, including minimal
access, port access, robotics, video-assisted, etc.
• Goal is to improve cosmetic results.
• These approaches are not associated with decreased
morbidity or mortality.
J Cardiovasc Thorac Res, 2014, 6(4), 205-210
cosmesis has now become a
concern to surgeons and
patients especially among
young females.
Surgery vs. Device closure
• Mild complications: small pericardial effusions, headaches, AV delay, atrial rhythm
disturbances
• Moderate complications: pneumonia, paroxysmal SVT, AV junctional rhythm
• Severe complications: bleeding requiring reoperation, transient neurologic events.
Device closure is associated with lower complication rate.
Bialkowski J, et al. Tex Heart Inst J 2004; 31: 220-3.
• Successful closure is achieved by both methods.
• Device closure results in lower rate of complication and hospital stay
• Cost of the procedure tends to be higher than surgery.
J Cardiovasc Thorac Res, 2014, 6(4), 205-210
Pakistan
Benefit of device closure
• Avoidance of surgery
• Avoidance of pain
• Avoidance of
cardiopulmonary bypass and
its risk
• Residual thoracotomy scar
• Short time of procedure
• Rapid recovery
• Shorter hospital stay
Safe, Simple and Effective
Study in Canada shows decrease in surgical closure
Device closure for ASD is
the
treatment of choice.
Comparable procedural success
Lower complications rate
Shorter hospital stays
No scar
We can easily conclude that
AS
How ASD device closure is done
•Proper ECHO evaluation to look for indication and
contraindication.
•Proper ECHO to evaluate and size of the ASD.
•Transesophageal ECHO to evaluate the rims
TEE Three views for ASD Device closure
Four chamber view for
AV and Posterior rim
Bicaval view for IVC and
SVC rim
Short axis 45Âş Aortic and
posterior rim
TEE evaluation of ASD rims
TEE evaluation should begin in the mid-esophageal 4-chamber view at 0Âş
Mid-esophageal Four-Chamber View.
• Relation of ASD to the AV
valves.
• Larger devices used to
close secundum ASD can
interfere AV valve
function.
Short Axis view mid-esophageal level, at 45-60Âş
Mid-esophageal short axis view
• mid-esophageal level, at
45Âş with a leftward
(counter-clock) rotation
of the probe.
• To view the Aortic rim
• Though Aortic rim in
absent in many patients.
• Is not important.
Bicaval view:provides an excellent view of IAS
Bicaval view
• From the mid-esophageal four-
chamber view, the multiplane
angle is rotated approximately
90 to 120. With slight clockwise
rotation of the shaft of the
probe),
• To identify IVC and SVC.
Which rim is important
• Inferior rim in particular must be of
adequate size for successful
transcatheter closure.
• Absent IVC rim is contraindication for
device closure.
How to size the ASD?
• Correct sizing of the ASD is crucial to select the ideal ASD device.
• ASD size changes during the cardiac cycle
• must be measured at the end of ventricular systole.
• The defect should not be measured with Color Doppler (CD), as this
technique leads to overestimation of true ASD size.
How to size the ASD?
• It is recommended to measure the
defect in three views with TEE.
• At least in two orthogonal views.
• Maximal transverse diameter in 4-
chamber view.
• Maximal longitudinal diameter in the
bi-caval view.
How to choose the ideal ASD Device size?
Sizing balloon
• Ideal way
• Add cost
• 1 to 2 mm bigger than the sizing
balloon diameter-stop flow
diameter
Simple way formula
• Maximum size of ASD + 1 to
2mm for good rims
• Maximum size of ASD + 2 to
4mm if absent aortic rim or
floopy rims.
How to choose the ideal Device size?
ASD size
• <16 mm
• 17 to 32
• >32
• Limited rim (inferior,posterior ,or the
anterior superior )
Device size
• Same size
• ASD size +2mm
• ASD size + 4mm
• 3 or 4 mm more than ASD
Practical Handbook of Advanced Interventional Cardiology
How we size the ASD and decide the ASD device
Four chamber view
Short axis view
Bi-caval view
Four Chamber view Short Axis view Bi-caval view
How we select the device size?
24mm
ASD closure steps
• After we choose the ideal ASD device.
• Device closure procedure starts in the cathlab.
• Selection of ideal delivery system
ASD is crossed with a Judkin’s right or
MP catheter.
catheter tip is positioned in the left
upper pulmonary vein (LUPV)
A floppy tip Amplatz Super stiff guide
wire placed in the LUPV.
An Amplatzer delivery sheath pushed over the
Superstiff wire into the mouth of the LSPV.
Delivery sheath advanced over the dilator
into the mouth of LSPV.
Delivery sheath positioned in the LA just
outside the LSPV.
Device is passed through the delivery sheath.
LA disk of device deployed in LA.
LA disk pulled back against the interatrial
septum.
Delivery sheath “peeled” back over the
loading cable to allow release of the waist
and RA disk.
Final position of the device in anteroposterior
projection
Amplatzer wire and delivery system in LUPV Delivery System
Device deployment Device deployed
Before the release of the device ECHO/TEE evaluation in most
Release of Device After release
Difficult ASD for device closure
• Deficient aortic and other rims
• Floppy, thin and aneurysmal septal rims
• Large ASD >35mm
• Small child with large ASD
• Multiple ASD
By conventional definition, a margin 5 mm is considered to be adequate.
ASD with deficient aortic rim (42.1%).1
1. Catheter Cardiovasc Interv 2001;53:386
–91.
Option in difficult ASD closure
Reason for difficulty in Absent or floppy rims
Device should come towards the IAS parallel
Presentation1.pdf
Left upper pulmonary vein for absent aortic rim
RUPV for absent Aortic rim with or without posterior rim
Deficient posterior rim
Right upper pulmonary vein technique Left atrial roof technique
Presentation1.pdf
• For deficient aortic and posterior rim
• Aortic end of the LA disk protuse
into RA during deployment.
• LA disc becomes parallel to septum
prevents protrusion of LA disc to RA.
LA roof technique
Deficient rims or thins rims
Wire assist technique
Catheter Assist technique
Multipurpose Catheter or a dilator catheter is advanced into the LA to prevent the LA disc from prolapsing
into the RA.
Balloon Assisted technique
Balloon prevents the prolapse of LA disc into RA
Take home message
• ASD device closure is a preferred treatment option in suitable ASD secundum.
• ASD device closure is safe, effective.
• It is the most cosmetic option available in the treatment of ASD.
Thank you

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Presentation1.pdf

  • 1. ASD Device Closure Why and How Dr. Chandra Mani Adhikari Cardiologist Shahid Gangalal National Heart Centre Associate Professor National Academy of Medical Sciences
  • 2. ASD secundum • Accounts for 10% of congenital heart disease at birth. •As much as 30% to 40% in adults who present with congenital heart disease. •More frequent in Females. J Cardiovasc Ultrasound 2007;15(1):1-7
  • 3. Surgical closure for ASD • For many years has been the gold standard treatment. • is a safe and effective with negligible mortality. N Engl J Med 2000;342:256-63.
  • 4. Surgical closure is associated with morbidity • Bypass related complications • Sternotomy/thoracotomy • Scar (specially young unmarried patients) N Engl J Med 1990;323:1645-50.
  • 5. Even the surgeon needs to think of cosmetic things • As most of the patients are young females • Emphasis has been placed on shorter incisions • “less” or “minimally” invasive techniques, including minimal access, port access, robotics, video-assisted, etc. • Goal is to improve cosmetic results. • These approaches are not associated with decreased morbidity or mortality. J Cardiovasc Thorac Res, 2014, 6(4), 205-210
  • 6. cosmesis has now become a concern to surgeons and patients especially among young females.
  • 7. Surgery vs. Device closure • Mild complications: small pericardial effusions, headaches, AV delay, atrial rhythm disturbances • Moderate complications: pneumonia, paroxysmal SVT, AV junctional rhythm • Severe complications: bleeding requiring reoperation, transient neurologic events. Device closure is associated with lower complication rate. Bialkowski J, et al. Tex Heart Inst J 2004; 31: 220-3.
  • 8. • Successful closure is achieved by both methods. • Device closure results in lower rate of complication and hospital stay • Cost of the procedure tends to be higher than surgery. J Cardiovasc Thorac Res, 2014, 6(4), 205-210 Pakistan
  • 9. Benefit of device closure • Avoidance of surgery • Avoidance of pain • Avoidance of cardiopulmonary bypass and its risk • Residual thoracotomy scar • Short time of procedure • Rapid recovery • Shorter hospital stay Safe, Simple and Effective
  • 10. Study in Canada shows decrease in surgical closure
  • 11. Device closure for ASD is the treatment of choice. Comparable procedural success Lower complications rate Shorter hospital stays No scar We can easily conclude that AS
  • 12. How ASD device closure is done •Proper ECHO evaluation to look for indication and contraindication. •Proper ECHO to evaluate and size of the ASD. •Transesophageal ECHO to evaluate the rims
  • 13. TEE Three views for ASD Device closure Four chamber view for AV and Posterior rim Bicaval view for IVC and SVC rim Short axis 45Âş Aortic and posterior rim
  • 14. TEE evaluation of ASD rims
  • 15. TEE evaluation should begin in the mid-esophageal 4-chamber view at 0Âş
  • 16. Mid-esophageal Four-Chamber View. • Relation of ASD to the AV valves. • Larger devices used to close secundum ASD can interfere AV valve function.
  • 17. Short Axis view mid-esophageal level, at 45-60Âş
  • 18. Mid-esophageal short axis view • mid-esophageal level, at 45Âş with a leftward (counter-clock) rotation of the probe. • To view the Aortic rim • Though Aortic rim in absent in many patients. • Is not important.
  • 19. Bicaval view:provides an excellent view of IAS
  • 20. Bicaval view • From the mid-esophageal four- chamber view, the multiplane angle is rotated approximately 90 to 120. With slight clockwise rotation of the shaft of the probe), • To identify IVC and SVC.
  • 21. Which rim is important • Inferior rim in particular must be of adequate size for successful transcatheter closure. • Absent IVC rim is contraindication for device closure.
  • 22. How to size the ASD? • Correct sizing of the ASD is crucial to select the ideal ASD device. • ASD size changes during the cardiac cycle • must be measured at the end of ventricular systole. • The defect should not be measured with Color Doppler (CD), as this technique leads to overestimation of true ASD size.
  • 23. How to size the ASD? • It is recommended to measure the defect in three views with TEE. • At least in two orthogonal views. • Maximal transverse diameter in 4- chamber view. • Maximal longitudinal diameter in the bi-caval view.
  • 24. How to choose the ideal ASD Device size? Sizing balloon • Ideal way • Add cost • 1 to 2 mm bigger than the sizing balloon diameter-stop flow diameter Simple way formula • Maximum size of ASD + 1 to 2mm for good rims • Maximum size of ASD + 2 to 4mm if absent aortic rim or floopy rims.
  • 25. How to choose the ideal Device size? ASD size • <16 mm • 17 to 32 • >32 • Limited rim (inferior,posterior ,or the anterior superior ) Device size • Same size • ASD size +2mm • ASD size + 4mm • 3 or 4 mm more than ASD Practical Handbook of Advanced Interventional Cardiology
  • 26. How we size the ASD and decide the ASD device
  • 30. Four Chamber view Short Axis view Bi-caval view How we select the device size? 24mm
  • 31. ASD closure steps • After we choose the ideal ASD device. • Device closure procedure starts in the cathlab. • Selection of ideal delivery system
  • 32. ASD is crossed with a Judkin’s right or MP catheter. catheter tip is positioned in the left upper pulmonary vein (LUPV) A floppy tip Amplatz Super stiff guide wire placed in the LUPV.
  • 33. An Amplatzer delivery sheath pushed over the Superstiff wire into the mouth of the LSPV. Delivery sheath advanced over the dilator into the mouth of LSPV.
  • 34. Delivery sheath positioned in the LA just outside the LSPV. Device is passed through the delivery sheath.
  • 35. LA disk of device deployed in LA. LA disk pulled back against the interatrial septum.
  • 36. Delivery sheath “peeled” back over the loading cable to allow release of the waist and RA disk. Final position of the device in anteroposterior projection
  • 37. Amplatzer wire and delivery system in LUPV Delivery System
  • 39. Before the release of the device ECHO/TEE evaluation in most Release of Device After release
  • 40. Difficult ASD for device closure • Deficient aortic and other rims • Floppy, thin and aneurysmal septal rims • Large ASD >35mm • Small child with large ASD • Multiple ASD By conventional definition, a margin 5 mm is considered to be adequate. ASD with deficient aortic rim (42.1%).1 1. Catheter Cardiovasc Interv 2001;53:386 –91.
  • 41. Option in difficult ASD closure
  • 42. Reason for difficulty in Absent or floppy rims Device should come towards the IAS parallel
  • 44. Left upper pulmonary vein for absent aortic rim
  • 45. RUPV for absent Aortic rim with or without posterior rim
  • 46. Deficient posterior rim Right upper pulmonary vein technique Left atrial roof technique
  • 48. • For deficient aortic and posterior rim • Aortic end of the LA disk protuse into RA during deployment. • LA disc becomes parallel to septum prevents protrusion of LA disc to RA.
  • 50. Deficient rims or thins rims
  • 52. Catheter Assist technique Multipurpose Catheter or a dilator catheter is advanced into the LA to prevent the LA disc from prolapsing into the RA.
  • 53. Balloon Assisted technique Balloon prevents the prolapse of LA disc into RA
  • 54. Take home message • ASD device closure is a preferred treatment option in suitable ASD secundum. • ASD device closure is safe, effective. • It is the most cosmetic option available in the treatment of ASD.