This document summarizes a research study that aims to compare the effectiveness of clinical and pharmacological trials in diagnosing Alzheimer's disease. The study will involve two groups in the clinical trial - one with a history of cardiovascular conditions and one without. In the pharmacological trial, there will be four groups - two with cardiovascular conditions receiving either treatment or no treatment, and two without. The study hypothesizes that cardiovascular disease increases Alzheimer's risk and that related drugs may negatively impact dementia development in younger patients. It aims to show pharmacological trials more accurately diagnose Alzheimer's and that cardiovascular conditions increase disease risk before age 65.